7CLG
 
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4C7A
 | | Crystal structure of the Smoothened CRD, selenomethionine-labeled | | 分子名称: | SMOOTHENED, SODIUM ION, ZINC ION | | 著者 | Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Covey, D.F, Rohatgi, R, Siebold, C. | | 登録日 | 2013-09-20 | | 公開日 | 2013-11-06 | | 最終更新日 | 2013-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling
Elife, 2, 2013
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4C79
 | | Crystal structure of the Smoothened CRD, native | | 分子名称: | SMOOTHENED, SODIUM ION, ZINC ION | | 著者 | Nachtergaele, S, Whalen, D.M, Mydock, L.K, Zhao, Z, Malinauskas, T, Krishnan, K, Ingham, P.W, Covey, D.F, Rohatgi, R, Siebold, C. | | 登録日 | 2013-09-20 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Structure and Function of the Smoothened Extracellular Domain in Vertebrate Hedgehog Signaling
Elife, 2, 2013
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2UUZ
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8IJO
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8IK4
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8IJP
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8IKD
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8IK8
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1X1V
 | | Structure Of Banana Lectin- Methyl-Alpha-Mannose Complex | | 分子名称: | HEXANE-1,6-DIOL, ZINC ION, lectin, ... | | 著者 | Singh, D.D, Saikrishnan, K, Kumar, P, Surolia, A, Sekar, K, Vijayan, M. | | 登録日 | 2005-04-14 | | 公開日 | 2005-11-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Unusual sugar specificity of banana lectin from Musa paradisiaca and its probable evolutionary origin. Crystallographic and modelling studies
Glycobiology, 15, 2005
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7DSU
 | | Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V | | 分子名称: | 1,2-ETHANEDIOL, Mbo45V, SINEFUNGIN | | 著者 | Ahmed, I, Chouhan, O.P, Gopinath, A, Morgan, R.D, Bhagat, K, Singh, A, Saikrishnan, K. | | 登録日 | 2021-01-02 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of Mod subunit of the Type III restriction-modification enzyme Mbo45V
To Be Published
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7NFU
 | | Crystal structure of C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | | 分子名称: | GLYCEROL, Nucleoid occlusion protein, SULFATE ION | | 著者 | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | | 登録日 | 2021-02-07 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc.
Mol.Cell, 81, 2021
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7NG0
 | | Crystal structure of N- and C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | | 分子名称: | Nucleoid occlusion protein, SULFATE ION | | 著者 | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | | 登録日 | 2021-02-08 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc.
Mol.Cell, 81, 2021
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6HZ6
 | | Structure of McrBC without DNA binding domains (Class 2) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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6HZ5
 | | Structure of McrBC without DNA binding domains (Class 1) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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6HZ8
 | | Structure of McrBC without DNA binding domains (Class 4) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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6HZ7
 | | Structure of McrBC without DNA binding domains (Class 3) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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6HZ9
 | | Structure of McrBC without DNA binding domains (Class 5) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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6HZ4
 | | Structure of McrBC without DNA binding domains (one half of the full complex) | | 分子名称: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | | 登録日 | 2018-10-22 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
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4XQK
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2UV1
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5SSX
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5SSY
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4Y14
 | | Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide, CHLORIDE ION, ... | | 著者 | Choy, M.S, Connors, C, Page, R, Peti, W. | | 登録日 | 2015-02-06 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | PTP1B inhibition suggests a therapeutic strategy for Rett syndrome.
J.Clin.Invest., 125, 2015
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7ZI0
 | | Structure of human Smoothened in complex with cholesterol and SAG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, ... | | 著者 | Byrne, E.F.X, Woolley, R.E, Ansell, B, Sansom, M.S.P, Newstead, S, Siebold, C. | | 登録日 | 2022-04-07 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Sci Adv, 8, 2022
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