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5ELT
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BU of 5elt by Molmil
Structure of the QUA1-KH domain of T-STAR in complex with UAAU RNA
分子名称: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
著者Dominguez, C, Feracci, M.
登録日2015-11-05
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
5EMO
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BU of 5emo by Molmil
Structure of the star domain of T-STAR in complex with AUUAAA RNA
分子名称: KH domain-containing, RNA-binding, signal transduction-associated protein 3, ...
著者Dominguez, C, Feracci, M.
登録日2015-11-06
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nat Commun, 7, 2016
6E0V
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BU of 6e0v by Molmil
Apo crystal structure of the colanidase tailspike protein gp150 of Phage Phi92
分子名称: 1,2-ETHANEDIOL, Bacteriophage Phi92 gp150, CHLORIDE ION, ...
著者Leiman, P.G, Browning, C, Gerardy-Schahn, R, Shneider, M.M, Plattner, M, Schwarzer, D.
登録日2018-07-07
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the colanidase tailspike protein gp150 of Phage Phi92 complexed with one repeating unit of colanic acid
To Be Published
6TUB
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BU of 6tub by Molmil
Beta-endorphin amyloid fibril
分子名称: Beta-endorphin
著者Verasdonck, J, Seuring, C, Gath, J, Ghosh, D, Nespovitaya, N, Waelti, M.A, Maji, S, Cadalbert, R, Boeckmann, A, Guentert, P, Meier, B.H, Riek, R.
登録日2020-01-05
公開日2020-10-28
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献The three-dimensional structure of human beta-endorphin amyloid fibrils.
Nat.Struct.Mol.Biol., 27, 2020
8AWP
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BU of 8awp by Molmil
Crystal structure of a manganese-containing cupin (tm1459) from Thermotoga maritima, variant 208 (V19I/R23H/M38I/I60F/C106Q)
分子名称: Cupin_2 domain-containing protein
著者Grininger, C, Steiner, K, Gruber, K, Pavkov-Keller, T.
登録日2022-08-30
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.595 Å)
主引用文献Engineering TM1459 for Stabilisation against Inactivation by Amino Acid Oxidation
Chem Ing Tech, 2023
8AWN
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BU of 8awn by Molmil
Crystal structure of a manganese-containing cupin (tm1459) from Thermotoga maritima, variant C106Q
分子名称: CHLORIDE ION, Cupin_2 domain-containing protein
著者Grininger, C, Steiner, K, Gruber, K, Pavkov-Keller, T.
登録日2022-08-30
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Engineering TM1459 for Stabilisation against Inactivation by Amino Acid Oxidation
Chem Ing Tech, 2023
6E0W
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BU of 6e0w by Molmil
Crystal structure of the colanidase tailspike protein gp150 of Phage Phi92 complexed with one repeating unit of colanic acid
分子名称: 1,2-ETHANEDIOL, 1,5-anhydro-4,6-O-[(1R)-1-carboxyethylidene]-D-galactitol, Bacteriophage Phi92 gp150, ...
著者Plattner, M, Browning, C, Gerardy-Schahn, R, Shneider, M.M, Leiman, P.G, Schwarzer, D.
登録日2018-07-07
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Crystal structure of the colanidase tailspike protein gp150 of Phage Phi92 complexed with one repeating unit of colanic acid
To Be Published
6PT0
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BU of 6pt0 by Molmil
Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2
分子名称: CHOLESTEROL, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, T.H, Xing, C, Zhuang, Y, Feng, Z, Zhou, X.E, Chen, M, Wang, L, Meng, X, Xue, Y, Wang, J, Liu, H, McGuire, T, Zhao, G, Melcher, K, Zhang, C, Xu, H.E, Xie, X.Q.
登録日2019-07-14
公開日2020-02-12
最終更新日2020-03-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Cell, 180, 2020
4A0D
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BU of 4a0d by Molmil
Structure of unliganded human PARG catalytic domain
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M.
登録日2011-09-08
公開日2012-10-17
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
4B1J
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BU of 4b1j by Molmil
Structure of human PARG catalytic domain in complex with ADP-HPD
分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M.
登録日2012-07-10
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
4B1H
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BU of 4b1h by Molmil
Structure of human PARG catalytic domain in complex with ADP-ribose
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, BETA-MERCAPTOETHANOL, GLYCEROL, ...
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Smith, G, Tucker, J.A, Watson, M.
登録日2012-07-10
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
4B1I
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BU of 4b1i by Molmil
Structure of human PARG catalytic domain in complex with OA-ADP-HPD
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 8-n-octylamino-adenosine diphosphate hydroxypyrrolidinediol, GLYCEROL, ...
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, Johnson, T, McAlister, M, Smith, G, Tucker, J.A, Watson, M.
登録日2012-07-10
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
4GCR
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BU of 4gcr by Molmil
STRUCTURE OF THE BOVINE EYE LENS PROTEIN GAMMA-B (GAMMA-II)-CRYSTALLIN AT 1.47 ANGSTROMS
分子名称: GAMMA-B CRYSTALLIN
著者Slingsby, C, Najmudin, S, Nalini, V, Driessen, H.P.C, Blundell, T.L, Moss, D.S, Lindley, P.
登録日1992-04-02
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structure of the bovine eye lens protein gammaB(gammaII)-crystallin at 1.47 A.
Acta Crystallogr.,Sect.D, 49, 1993
4B1G
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BU of 4b1g by Molmil
Structure of unliganded human PARG catalytic domain
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, SULFATE ION
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M.
登録日2012-07-10
公開日2012-12-19
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
1YTQ
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BU of 1ytq by Molmil
Structure of Native Human Beta B2 Crystallin
分子名称: Beta crystallin B2
著者Slingsby, C, Smith, M.A, Bateman, O.A.
登録日2005-02-10
公開日2006-01-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mutation of interfaces in domain-swapped human betaB2-crystallin
Protein Sci., 16, 2007
7BGJ
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BU of 7bgj by Molmil
C. thermophilum Pyruvate Dehydrogenase Complex Core
分子名称: Acetyltransferase component of pyruvate dehydrogenase complex
著者Tueting, C, Kastritis, P.L.
登録日2021-01-07
公開日2021-02-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts.
Cell Rep, 34, 2021
1GXK
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BU of 1gxk by Molmil
SMC hinge domain from T. maritima w/o coiled coil, P212121 crystal form
分子名称: CHROMOSOME SEGREGATION SMC PROTEIN
著者Lowe, J, Haering, C, Nasmyth, K.
登録日2002-04-07
公開日2002-04-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Architecture of Smc Proteins and the Yeast Cohesin Complex
Mol.Cell, 9, 2002
1GXL
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BU of 1gxl by Molmil
SMC hinge domain from T. maritima with coiled coil
分子名称: CHROMOSOME SEGREGATION SMC PROTEIN
著者Lowe, J, Haering, C, Nasmyth, K.
登録日2002-04-07
公開日2002-04-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Architecture of Smc Proteins and the Yeast Cohesin Complex
Mol.Cell, 9, 2002
1GXJ
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BU of 1gxj by Molmil
SMC hinge domain from T. maritima w/o coiled coil
分子名称: CHROMOSOME SEGREGATION SMC PROTEIN
著者Lowe, J, Haering, C, Nasmyth, K.
登録日2002-04-07
公開日2002-04-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Architecture of Smc Proteins and the Yeast Cohesin Complex
Mol.Cell, 9, 2002
2R40
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BU of 2r40 by Molmil
Crystal structure of 20E bound EcR/USP
分子名称: (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, CITRATE ANION, Ecdysone Receptor, ...
著者Moras, D, Billas, I.M.L, Browning, C.
登録日2007-08-30
公開日2007-10-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor
J.Biol.Chem., 282, 2007
3CJ0
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BU of 3cj0 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
7ER9
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BU of 7er9 by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Febuxostat (TEI)
分子名称: 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7ERE
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BU of 7ere by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Pyrantel Pamoate (PPA)
分子名称: 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022

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