1JB2
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![BU of 1jb2 by Molmil](/molmil-images/mine/1jb2) | CRYSTAL STRUCTURE OF NTF2 M84E MUTANT | 分子名称: | NUCLEAR TRANSPORT FACTOR 2 | 著者 | Chaillan-Huntington, C, Butler, P.J, Huntington, J.A, Akin, D, Feldherr, C, Stewart, M. | 登録日 | 2001-06-01 | 公開日 | 2002-03-13 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | NTF2 monomer-dimer equilibrium. J.Mol.Biol., 314, 2001
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1JB5
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![BU of 1jb5 by Molmil](/molmil-images/mine/1jb5) | CRYSTAL STRUCTURE OF NTF2 M118E MUTANT | 分子名称: | NUCLEAR TRANSPORT FACTOR 2 | 著者 | Chaillan-Huntington, C, Butler, P.J, Huntington, J.A, Akin, D, Feldherr, C, Stewart, M. | 登録日 | 2001-06-01 | 公開日 | 2002-03-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | NTF2 monomer-dimer equilibrium. J.Mol.Biol., 314, 2001
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1JB4
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![BU of 1jb4 by Molmil](/molmil-images/mine/1jb4) | CRYSTAL STRUCTURE OF NTF2 M102E MUTANT | 分子名称: | NUCLEAR TRANSPORT FACTOR 2 | 著者 | Chaillan-Huntington, C, Butler, P.J, Huntington, J.A, Akin, D, Feldherr, C, Stewart, M. | 登録日 | 2001-06-01 | 公開日 | 2002-03-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | NTF2 monomer-dimer equilibrium. J.Mol.Biol., 314, 2001
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4RBM
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![BU of 4rbm by Molmil](/molmil-images/mine/4rbm) | Porphyromonas gingivalis gingipain K (Kgp) catalytic and immunoglobulin superfamily-like domains | 分子名称: | (3S)-3,7-diaminoheptan-2-one, ACETATE ION, AZIDE ION, ... | 著者 | de Diego, I, Veillard, F, Sztukowska, M.N, Guevara, T, Potempa, B, Pomowski, A, Huntington, J.A, Potempa, J, Gomis-Ruth, F.X. | 登録日 | 2014-09-12 | 公開日 | 2014-10-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and Mechanism of Cysteine Peptidase Gingipain K (Kgp), a Major Virulence Factor of Porphyromonas gingivalis in Periodontitis. J.Biol.Chem., 289, 2014
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1OYH
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![BU of 1oyh by Molmil](/molmil-images/mine/1oyh) | Crystal Structure of P13 Alanine Variant of Antithrombin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... | 著者 | Johnson, D.J.D, Huntington, J.A. | 登録日 | 2003-04-04 | 公開日 | 2004-04-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | The influence of hinge region residue Glu-381 on antithrombin allostery and metastability J.Biol.Chem., 279, 2004
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1OC0
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![BU of 1oc0 by Molmil](/molmil-images/mine/1oc0) | plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN | 著者 | Read, R.J, Zhou, A, Huntington, J.A, Pannu, N.S, Carrell, R.W. | 登録日 | 2003-02-03 | 公開日 | 2003-06-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration Nat.Struct.Biol., 10, 2003
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5MUN
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![BU of 5mun by Molmil](/molmil-images/mine/5mun) | Structural insight into zymogenic latency of gingipain K from Porphyromonas gingivalis. | 分子名称: | AZIDE ION, Lys-gingipain W83 | 著者 | Pomowski, A, Uson, I, Nowakovska, Z, Veillard, F, Sztukowska, M.N, Guevara, T, Goulas, T, Mizgalska, D, Nowak, M, Potempa, B, Huntington, J.A, Potempa, J, Gomis-Ruth, F.X. | 登録日 | 2017-01-13 | 公開日 | 2017-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights unravel the zymogenic mechanism of the virulence factor gingipain K from Porphyromonas gingivalis, a causative agent of gum disease from the human oral microbiome. J. Biol. Chem., 292, 2017
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1XMN
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![BU of 1xmn by Molmil](/molmil-images/mine/1xmn) | Crystal structure of thrombin bound to heparin | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... | 著者 | Carter, W.J, Cama, E, Huntington, J.A. | 登録日 | 2004-10-04 | 公開日 | 2004-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of thrombin bound to heparin J.Biol.Chem., 280, 2005
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2AFQ
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![BU of 2afq by Molmil](/molmil-images/mine/2afq) | |
3K65
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![BU of 3k65 by Molmil](/molmil-images/mine/3k65) | |
2GD4
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![BU of 2gd4 by Molmil](/molmil-images/mine/2gd4) | Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ... | 著者 | Johnson, D.J, Li, W, Adams, T.E, Huntington, J.A. | 登録日 | 2006-03-15 | 公開日 | 2006-05-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. Embo J., 25, 2006
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2HI9
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![BU of 2hi9 by Molmil](/molmil-images/mine/2hi9) | |
3NDD
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![BU of 3ndd by Molmil](/molmil-images/mine/3ndd) | |
1R1L
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![BU of 1r1l by Molmil](/molmil-images/mine/1r1l) | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | 登録日 | 2003-09-24 | 公開日 | 2004-10-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Serpins and the design of peptides to block intermolecular beta-linkages To be Published
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1RD3
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![BU of 1rd3 by Molmil](/molmil-images/mine/1rd3) | 2.5A Structure of Anticoagulant Thrombin Variant E217K | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PHOSPHATE ION, ... | 著者 | Carter, W.J, Myles, T, Leung, L.L, Huntington, J.A. | 登録日 | 2003-11-05 | 公開日 | 2004-05-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery J.Biol.Chem., 279, 2004
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1T1F
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![BU of 1t1f by Molmil](/molmil-images/mine/1t1f) | |
3DY0
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![BU of 3dy0 by Molmil](/molmil-images/mine/3dy0) | Crystal Structure of Cleaved PCI Bound to Heparin | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ... | 著者 | Li, W, Huntington, J.A. | 登録日 | 2008-07-25 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The heparin binding site of protein C inhibitor is protease-dependent. J.Biol.Chem., 283, 2008
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1TB6
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![BU of 1tb6 by Molmil](/molmil-images/mine/1tb6) | 2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfonato-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-alpha-L-idopyranuronic acid-(1-4)-methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, W, Johnson, D.J, Esmon, C.T, Huntington, J.A. | 登録日 | 2004-05-19 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat.Struct.Mol.Biol., 11, 2004
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3GIS
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![BU of 3gis by Molmil](/molmil-images/mine/3gis) | |
1JMJ
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![BU of 1jmj by Molmil](/molmil-images/mine/1jmj) | Crystal Structure of Native Heparin Cofactor II | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEPARIN COFACTOR II, ... | 著者 | Baglin, T.P, Carrell, R.W, Church, F.C, Huntington, J.A. | 登録日 | 2001-07-18 | 公開日 | 2002-08-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99, 2002
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1JVQ
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![BU of 1jvq by Molmil](/molmil-images/mine/1jvq) | Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop peptide, and an exogenous tetrapeptide | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. | 登録日 | 2001-08-31 | 公開日 | 2003-06-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | How small peptides block and reverse serpin polymerisation J.Mol.Biol., 342, 2004
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1JMO
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![BU of 1jmo by Molmil](/molmil-images/mine/1jmo) | Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Baglin, T.P, Carrell, R.W, Esmon, C.T, Huntington, J.A. | 登録日 | 2001-07-19 | 公開日 | 2002-08-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99, 2002
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1LK6
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![BU of 1lk6 by Molmil](/molmil-images/mine/1lk6) | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. | 登録日 | 2002-04-24 | 公開日 | 2003-06-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Serpin Polymerization Is Prevented by a Hydrogen Bond Network That Is Centered on His-334 and Stabilized by Glycerol J.Biol.Chem., 278, 2003
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4BXS
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![BU of 4bxs by Molmil](/molmil-images/mine/4bxs) | Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Lechtenberg, B.C, Murray-Rust, T.A, Johnson, D.J.D, Adams, T.E, Krishnaswamy, S, Camire, R.M, Huntington, J.A. | 登録日 | 2013-07-15 | 公開日 | 2013-07-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis. Blood, 122, 2013
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4CH8
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![BU of 4ch8 by Molmil](/molmil-images/mine/4ch8) | High-salt crystal structure of a thrombin-GpIbalpha peptide complex | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | 著者 | Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A. | 登録日 | 2013-11-29 | 公開日 | 2013-12-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Gpibalpha Interacts Exclusively with Exosite II of Thrombin J.Mol.Biol., 426, 2014
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