7Q1D
 
 | | Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, ... | | 著者 | Pontillo, N, Guskov, A. | | 登録日 | 2021-10-18 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa
To Be Published
|
|
7Q1X
 | | Acetyltrasferase(3) type IIIa in complex with neomycin B | | 分子名称: | Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Pontillo, N, Guskov, A. | | 登録日 | 2021-10-21 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism
To Be Published
|
|
7Q0Q
 | |
7NGH
 | | Structure of glutamate transporter homologue in complex with Sybody | | 分子名称: | ASPARTIC ACID, Proton/glutamate symporter, SDF family, ... | | 著者 | Arkhipova, V, Slotboom, D.J, Guskov, A. | | 登録日 | 2021-02-09 | | 公開日 | 2021-09-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Kinetic mechanism of Na + -coupled aspartate transport catalyzed by Glt Tk .
Commun Biol, 4, 2021
|
|
5MYJ
 | | Structure of 70S ribosome from Lactococcus lactis | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Franken, L.E, Oostergetel, G.T, Pijning, T, Puri, P, Boekema, E.J, Poolman, B, Guskov, A. | | 登録日 | 2017-01-26 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy.
Nat Commun, 8, 2017
|
|
8ODS
 | |
8QQZ
 | | Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 8.0 | | 分子名称: | Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE | | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A. | | 登録日 | 2023-10-06 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion.
Nat Commun, 15, 2024
|
|
8QR0
 | | Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 4.3 | | 分子名称: | Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE | | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A. | | 登録日 | 2023-10-06 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion.
Nat Commun, 15, 2024
|
|
7EHS
 | | Levansucrase from Brenneria sp. EniD 312 | | 分子名称: | GLYCEROL, Levansucrase, NONAETHYLENE GLYCOL, ... | | 著者 | Xu, W, Ni, D.W, Hou, X.D, Rao, Y.J, Pijning, T, Guskov, A, Mu, W.M. | | 登録日 | 2021-03-30 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity.
J.Agric.Food Chem., 70, 2022
|
|
7EHT
 | | Levansucrase from Brenneria sp. EniD 312 | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, Levansucrase, ... | | 著者 | Xu, W, Hou, X.D, Rao, Y.J, Pijning, T, Guskov, A, Mu, W.M. | | 登録日 | 2021-03-30 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity.
J.Agric.Food Chem., 70, 2022
|
|
7EHR
 | | Levansucrase from Brenneria sp. EniD 312 at 1.33 angstroms resolution | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Xu, W, Ni, D.W, Hou, X.D, Rao, Y.J, Pijning, T, Guskov, A, Mu, W.M. | | 登録日 | 2021-03-30 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Crystal Structure of Levansucrase from the Gram-Negative Bacterium Brenneria Provides Insights into Its Product Size Specificity.
J.Agric.Food Chem., 70, 2022
|
|
7PZY
 | | Structure of the vacant Candida albicans 80S ribosome | | 分子名称: | 1,4-DIAMINOBUTANE, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | | 登録日 | 2021-10-13 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome.
Sci Adv, 8, 2022
|
|
7Q0P
 | | Structure of the Candida albicans 80S ribosome in complex with anisomycin | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | | 登録日 | 2021-10-15 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome.
Sci Adv, 8, 2022
|
|
7Q0F
 | | Structure of Candida albicans 80S ribosome in complex with phyllanthoside | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | | 登録日 | 2021-10-14 | | 公開日 | 2022-05-18 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome.
Sci Adv, 8, 2022
|
|
7Q08
 | | Structure of Candida albicans 80S ribosome in complex with cycloheximide | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | | 登録日 | 2021-10-14 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome.
Sci Adv, 8, 2022
|
|
7Q0R
 | | Structure of the Candida albicans 80S ribosome in complex with blasticidin s | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | | 登録日 | 2021-10-16 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome.
Sci Adv, 8, 2022
|
|
8OQ2
 | | Binding of NADP to a formate dehydrogenase from Starkeya novella. | | 分子名称: | AZIDE ION, Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Partipilo, M, Whittaker, J.J, Pontillo, N, Guskov, A, Slotboom, D.J. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Binding of NADP to a formate dehydrogenase from Starkeya novella.
To Be Published
|
|
7P4I
 | |
4ZEF
 | |
5D0Y
 | |
8AFA
 | |
8Q5I
 | | Structure of Candida albicans 80S ribosome in complex with cephaeline | | 分子名称: | 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. | | 登録日 | 2023-08-09 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | | 主引用文献 | Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Biopolym Cell, 2023
|
|
8P3C
 | | Full length structure of BpMIP with bound inhibitor NJS227. | | 分子名称: | (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A. | | 登録日 | 2023-05-17 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains
To Be Published
|
|
8P3D
 | |
8P42
 | | Full length structure of TcMIP with bound inhibitor NJS227. | | 分子名称: | (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, Macrophage infectivity potentiator | | 著者 | Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A. | | 登録日 | 2023-05-19 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains
To Be Published
|
|
