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1G6P
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BU of 1g6p by Molmil
SOLUTION NMR STRUCTURE OF THE COLD SHOCK PROTEIN FROM THE HYPERTHERMOPHILIC BACTERIUM THERMOTOGA MARITIMA
分子名称: COLD SHOCK PROTEIN TMCSP
著者Kremer, W, Schuler, B, Harrieder, S, Geyer, M, Gronwald, W, Welker, C, Jaenicke, R, Kalbitzer, H.R.
登録日2000-11-07
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the cold-shock protein from the hyperthermophilic bacterium Thermotoga maritima.
Eur.J.Biochem., 268, 2001
2W2H
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BU of 2w2h by Molmil
Structural basis of transcription activation by the Cyclin T1-Tat-TAR RNA complex from EIAV
分子名称: 5'-R(*GP*CP*UP*CP*AP*GP*AP*UP*CP*UP *GP*CP*GP*GP*UP*CP*UP*GP*AP*GP*C)-3', CYCLIN-T1, MANGANESE (II) ION, ...
著者Anand, K, Geyer, M.
登録日2008-10-30
公開日2008-12-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural Insights Into the Cyclin T1-Tat-Tar RNA Transcription Activation Complex from Eiav.
Nat.Struct.Mol.Biol., 15, 2008
3RBB
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BU of 3rbb by Molmil
HIV-1 NEF protein in complex with engineered HCK SH3 domain
分子名称: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK
著者Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M.
登録日2011-03-29
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
Traffic, 12, 2011
6Z2G
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BU of 6z2g by Molmil
Crystal structure of human NLRP9 PYD
分子名称: NACHT, LRR and PYD domains-containing protein 9
著者Marleaux, M, Anand, K, Geyer, M.
登録日2020-05-15
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
Febs Lett., 594, 2020
3JVK
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BU of 3jvk by Molmil
Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, histone H3.3 peptide
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
3JVJ
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BU of 3jvj by Molmil
Crystal structure of the bromodomain 1 in mouse Brd4
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
3JVM
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BU of 3jvm by Molmil
Crystal structure of bromodomain 2 of mouse Brd4
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromodomain-containing protein 4
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
3JVL
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BU of 3jvl by Molmil
Crystal structure of bromodomain 2 of mouse Brd4
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromodomain-containing protein 4
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
3REB
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BU of 3reb by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK
著者Schulte, A, Blankenfeldt, W, Geyer, M.
登録日2011-04-04
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011
3MUL
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BU of 3mul by Molmil
Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Peptide of Histone H3.3
著者Vollmuth, F, Geyer, M.
登録日2010-05-03
公開日2010-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3MUK
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BU of 3muk by Molmil
Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, peptide of Histone H3.3
著者Vollmuth, F, Geyer, M.
登録日2010-05-03
公開日2010-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3REA
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BU of 3rea by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK
著者Schulte, A, Blankenfeldt, W, Geyer, M.
登録日2011-04-04
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011
3S9G
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BU of 3s9g by Molmil
Structure of human Hexim1 (delta stammer) coiled coil domain
分子名称: Protein HEXIM1
著者Bigalke, J.M, Blankenfeldt, W, Geyer, M.
登録日2011-06-01
公開日2011-10-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Dynamics of a Stabilized Coiled-Coil Domain in the P-TEFb Regulator Hexim1.
J.Mol.Biol., 414, 2011
2L1A
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BU of 2l1a by Molmil
Solution NMR structure of the N-terminal GTPase-like domain of dictyostelium discoideum Fomin C
分子名称: Formin-C
著者Dames, S.A, Schoenichen, A, Stephan, G, Geyer, M.
登録日2010-07-27
公開日2011-08-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C.
J.Biol.Chem., 286, 2011
5NUI
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BU of 5nui by Molmil
Crystal structure of SIVmac239 Nef in an ExxxLM endocytic sorting motif bound state
分子名称: Protein Nef, SER-GLN-ILE-LYS-ARG-LEU-LEU-SER
著者Manrique, S, Horenkamp, F.A, Anand, K, Geyer, M.
登録日2017-04-30
公開日2017-08-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Nat Commun, 8, 2017
5NUH
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BU of 5nuh by Molmil
Crystal structure of SIVmac239 Nef bound to an engineered Hck SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK,Tyrosine-protein kinase HCK
著者Horenkamp, F.A, Anand, K, Geyer, M.
登録日2017-04-30
公開日2017-08-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Nat Commun, 8, 2017
2GD7
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BU of 2gd7 by Molmil
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
分子名称: HEXIM1 protein
著者Dames, S.A.
登録日2006-03-15
公開日2007-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Proc.Natl.Acad.Sci.Usa, 104, 2007
8A90
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BU of 8a90 by Molmil
Crystal structure of FrsH
分子名称: ACETATE ION, FE (III) ION, GLYCEROL, ...
著者Schneberger, N, Wirtz, D.A, Cruesemann, M, Hagelueken, G.
登録日2022-06-27
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.574 Å)
主引用文献Adenylation Domain-Guided Recruitment of Trans- Acting Nonheme Monooxygenases in Nonribosomal Peptide Biosynthesis.
Acs Chem.Biol., 18, 2023
5ACB
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BU of 5acb by Molmil
Crystal Structure of the Human Cdk12-Cyclink Complex
分子名称: CYCLIN-DEPENDENT KINASE 12, CYCLIN-K, N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide
著者Dixon Clarke, S.E, Elkins, J.M, Pike, A.C.W, Mackenzie, A, Goubin, S, Strain-Damerell, C, Mahajan, P, Tallant, C, Chalk, R, Wiggers, H, Kopec, J, Fitzpatrick, F, Burgess-Brown, N, Carpenter, E.P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2015-08-14
公開日2016-06-15
最終更新日2016-10-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Covalent Targeting of Remote Cysteine Residues to Develop Cdk12 and Cdk13 Inhibitors.
Nat.Chem.Biol., 12, 2016
821P
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BU of 821p by Molmil
THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS
分子名称: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Scheidig, A.J, Krengel, U, Pai, E.F, Kabsch, W, Wittinghofer, A, Goody, R.S.
登録日1993-03-29
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
Biochemistry, 32, 1993
1I35
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BU of 1i35 by Molmil
SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF THE PROTEIN KINASE BYR2 FROM SCHIZOSACCHAROMYCES POMBE
分子名称: PROTEIN KINASE BYR2
著者Gronwald, W, Huber, F, Grunewald, P, Sporner, M, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R.
登録日2001-02-13
公開日2001-12-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe.
Structure, 9, 2001
8B0R
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BU of 8b0r by Molmil
Structure of the CalpL/cA4 complex
分子名称: Cyclic tetraadenosine monophosphate (cA4), SMODS-associated and fused to various effectors domain-containing protein, SULFATE ION, ...
著者Schneberger, N, Hagelueken, G.
登録日2022-09-08
公開日2022-11-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
8B0U
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BU of 8b0u by Molmil
Structure of the CalpL/T10 complex
分子名称: CalpT10, GLYCEROL, SAVED domain-containing protein, ...
著者Schneberger, N, Hagelueken, G.
登録日2022-09-08
公開日2022-11-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
7QDA
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Crystal structure of CalpL
分子名称: CalpL, SULFATE ION, TETRAETHYLENE GLYCOL, ...
著者Schneberger, N, Hagelueken, G.
登録日2021-11-26
公開日2022-11-16
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
7QE5
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Structure of the membrane domains of the sialic acid TRAP transporter HiSiaQM from Haemophilus influenzae
分子名称: Megabody3, Sialic acid TRAP transporter permease protein SiaT
著者Peter, M.F, Hagelueken, G.
登録日2021-12-01
公開日2022-07-27
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 13, 2022

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