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1E7K
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BU of 1e7k by Molmil
Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment
分子名称: 15.5 KD RNA BINDING PROTEIN, RNA (5'-R(*GP*CP*CP*AP*AP*UP*GP*AP*GP*GP*UP*UP*UP* AP*UP*CP*CP*GP*AP*GP*G*C(-3')
著者Vidovic, I, Nottrott, S, Harthmuth, K, Luhrmann, R, Ficner, R.
登録日2000-08-29
公開日2001-02-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment
Mol.Cell, 6, 2000
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
登録日2015-09-01
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
6ZM2
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BU of 6zm2 by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hamann, F, Ficner, R.
登録日2020-07-01
公開日2021-04-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases.
Acta Crystallogr D Struct Biol, 77, 2021
7B51
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BU of 7b51 by Molmil
Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528
分子名称: BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ...
著者Shaikhqasem, A, Ficner, R.
登録日2020-12-03
公開日2021-03-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP.
Acta Crystallogr.,Sect.F, 77, 2021
8ARU
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BU of 8aru by Molmil
Crystal Structure of human formylglycine generating enzyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Formylglycine-generating enzyme
著者Neumann, P, Dickmanns, A, Ficner, R, Rudolph, M.G.
登録日2022-08-17
公開日2023-08-23
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Crystal Structure of human formylglycine generating enzyme E130A mutant
To be published
4N3S
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BU of 4n3s by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (399-852) from Saccharomyces cerevisiae, apo form
分子名称: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 5B, GLYCEROL
著者Kuhle, B, Ficner, R.
登録日2013-10-07
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.832 Å)
主引用文献eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
4N3G
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BU of 4n3g by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (870-1116) from Chaetomium thermophilum, domains III and IV
分子名称: CHLORIDE ION, Eukaryotic translation initiation factor 5B-like protein, eIF5B(870-C), ...
著者Kuhle, B, Ficner, R.
登録日2013-10-07
公開日2014-07-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
4N3N
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BU of 4n3n by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (517-1116) from Chaetomium thermophilum, apo form
分子名称: Eukaryotic translation initiation factor 5B-like protein, eIF5B(517-C), LACTIC ACID
著者Kuhle, B, Ficner, R.
登録日2013-10-07
公開日2014-07-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
4NCN
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BU of 4ncn by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (517-858) from Chaetomium thermophilum in complex with GTP
分子名称: ACETIC ACID, Eukaryotic translation initiation factor 5B-like protein, GLYCEROL, ...
著者Kuhle, B, Ficner, R.
登録日2013-10-24
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
4NCL
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BU of 4ncl by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (517-970) from Chaetomium thermophilum in complex with GDP
分子名称: Eukaryotic translation initiation factor 5B-like protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kuhle, B, Ficner, R.
登録日2013-10-24
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.115 Å)
主引用文献eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
1PUD
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BU of 1pud by Molmil
TRNA-GUANINE TRANSGLYCOSYLASE
分子名称: TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
著者Romier, C, Reuter, K, Suck, D, Ficner, R.
登録日1996-06-28
公開日1997-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
EMBO J., 15, 1996
1QGV
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BU of 1qgv by Molmil
HUMAN SPLICEOSOMAL PROTEIN U5-15KD
分子名称: SPLICEOSOMAL PROTEIN U5-15KD
著者Reuter, K, Nottrott, S, Fabrizio, P, Luehrmann, R, Ficner, R.
登録日1999-05-06
公開日1999-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein.
J.Mol.Biol., 294, 1999
1WKF
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BU of 1wkf by Molmil
TRNA-GUANINE TRANSGLYCOSYLASE
分子名称: TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
著者Romier, C, Reuter, K, Suck, D, Ficner, R.
登録日1996-08-06
公開日1997-07-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
1WKE
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BU of 1wke by Molmil
TRNA-GUANINE TRANSGLYCOSYLASE
分子名称: TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
著者Romier, C, Reuter, K, Suck, D, Ficner, R.
登録日1996-08-06
公開日1997-07-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
1WKD
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BU of 1wkd by Molmil
TRNA-GUANINE TRANSGLYCOSYLASE
分子名称: TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
著者Romier, C, Reuter, K, Suck, D, Ficner, R.
登録日1996-08-06
公開日1997-07-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
5LTA
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BU of 5lta by Molmil
Crystal structure of the Prp43-ADP-BeF3-U7-RNA complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CACODYLATE ION, ...
著者Tauchert, M.J, Ficner, R.
登録日2016-09-06
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.621 Å)
主引用文献Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
5LTK
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BU of 5ltk by Molmil
Crystal structure of the Prp43-ADP-BeF3 complex (in hexagonal space group)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Tauchert, M.J, Ficner, R.
登録日2016-09-06
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.241 Å)
主引用文献Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
5LTJ
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BU of 5ltj by Molmil
Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Tauchert, M.J, Ficner, R.
登録日2016-09-06
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
7NQ4
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BU of 7nq4 by Molmil
Human tRNA guanine transglycosylase (TGT), RNA-bound covalent intermediate
分子名称: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ...
著者Sievers, K, Ficner, R.
登録日2021-03-01
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural and functional insights into human tRNA guanine transgylcosylase.
Rna Biol., 18, 2021
6YJ8
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BU of 6yj8 by Molmil
DarB-APO
分子名称: ACETATE ION, CBS domain-containing protein YkuL, DI(HYDROXYETHYL)ETHER
著者Heidemann, J.L, Neumann, P, Ficner, R.
登録日2020-04-02
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献DarB from B. subtilis
To Be Published
6YJ9
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BU of 6yj9 by Molmil
DarB in complex with 3'3'cGAMP
分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CBS domain-containing protein YkuL, CHLORIDE ION
著者Heidemann, J.L, Neumann, P, Ficner, R.
登録日2020-04-02
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献DarB from B. subtilis
To Be Published
6YJ7
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BU of 6yj7 by Molmil
DarB fom B. subtilis in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, CBS domain-containing protein YkuL, CHLORIDE ION
著者Heidemann, J.L, Neumann, P, Ficner, R.
登録日2020-04-02
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献DarB from B. subtilis
To Be Published
6YJA
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BU of 6yja by Molmil
DarB fom B. subtilis in complex with c-di-AMP
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, CBS domain-containing protein YkuL, ...
著者Heidemann, J.L, Neumann, P, Ficner, R.
登録日2020-04-02
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DarB from B. subtilis
To Be Published
7NZJ
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BU of 7nzj by Molmil
Structure of bsTrmB apo
分子名称: GLYCEROL, SODIUM ION, tRNA (guanine-N(7)-)-methyltransferase
著者Blersch, K.F, Ficner, R, Neumann, P.
登録日2021-03-24
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021
7NZI
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BU of 7nzi by Molmil
TrmB complex with SAH
分子名称: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase
著者Blersch, K.F, Ficner, R, Neumann, P.
登録日2021-03-24
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
Rna Biol., 18, 2021

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