4GXV
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4GXX
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6XGY
| Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state | 分子名称: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Chang, Y, Bhabha, G, Ekiert, D.C. | 登録日 | 2020-06-18 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
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6XGZ
| Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state | 分子名称: | 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... | 著者 | Chang, Y, Bhabha, G, Ekiert, D.C. | 登録日 | 2020-06-18 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation. Elife, 9, 2020
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6XBD
| Cryo-EM structure of MlaFEDB in nanodiscs with phospholipid substrates | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MSP1D1, Phospholipid ABC transporter permease protein MlaE, ... | 著者 | Coudray, N, Isom, G.L, MacRae, M.R, Saiduddin, M, Ekiert, D.C, Bhabha, G. | 登録日 | 2020-06-05 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structure of bacterial phospholipid transporter MlaFEDB with substrate bound. Elife, 9, 2020
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7UE2
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7UDK
| Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide | 分子名称: | 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4 | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-03-20 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDO
| Crystal structure of designed helical repeat protein RPB_LRP2_R4 (proteolysis fragment?), forming pseudopolymeric filaments | 分子名称: | 1,2-ETHANEDIOL, Designed helical repeat protein (DHR) RPB_LRP2_R4, PHOSPHATE ION | 著者 | Redler, R.L, Chang, Y, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-03-20 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDL
| Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide | 分子名称: | 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6 | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-03-20 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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7UDN
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7UDM
| Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide) | 分子名称: | 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6 | 著者 | Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-03-20 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | De novo design of modular peptide-binding proteins by superhelical matching. Nature, 616, 2023
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2LT7
| Solution NMR structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA | 分子名称: | DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... | 著者 | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H, Wilson, I.A, Wright, P.E. | 登録日 | 2012-05-15 | 公開日 | 2012-09-05 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
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7UPQ
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7UPP
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7UPO
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8FEE
| Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2) | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-12-06 | 公開日 | 2023-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
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8FEF
| Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-12-06 | 公開日 | 2023-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
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8FED
| Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | 登録日 | 2022-12-06 | 公開日 | 2023-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
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4F6N
| Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | 分子名称: | DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... | 著者 | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | 登録日 | 2012-05-15 | 公開日 | 2012-09-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F6M
| Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA | 分子名称: | DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... | 著者 | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | 登録日 | 2012-05-15 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc.Natl.Acad.Sci.USA, 109, 2012
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7MI8
| Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5 | 分子名称: | Fusion protein of Dynein and Endolysin | 著者 | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI3
| Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4 | 分子名称: | (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... | 著者 | Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
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7MI1
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3QL3
| Re-refined coordinates for PDB entry 1RX2 | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | 登録日 | 2011-02-02 | 公開日 | 2011-04-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332, 2011
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3QL0
| Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | 登録日 | 2011-02-02 | 公開日 | 2011-04-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332, 2011
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