6ZC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zc8 by Molmil](/molmil-images/mine/6zc8) | |
6ZC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zc4 by Molmil](/molmil-images/mine/6zc4) | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | 分子名称: | 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... | 著者 | Roske, Y, Heinemann, U, Oschkinat, H. | 登録日 | 2020-06-09 | 公開日 | 2021-06-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
|
|
6HQC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hqc by Molmil](/molmil-images/mine/6hqc) | |
1SS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ss6 by Molmil](/molmil-images/mine/1ss6) | Solution structure of SEP domain from human p47 | 分子名称: | NSFL1 cofactor p47 | 著者 | Soukenik, M, Leidert, M, Sievert, V, Buessow, K, Leitner, D, Labudde, D, Ball, L.J, Oschkinat, H. | 登録日 | 2004-03-23 | 公開日 | 2004-11-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L FEBS Lett., 576, 2004
|
|
8AIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8aif by Molmil](/molmil-images/mine/8aif) | |
6XYD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xyd by Molmil](/molmil-images/mine/6xyd) | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi | 分子名称: | CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... | 著者 | Roske, Y, Heinemann, U, Andrea, E.D. | 登録日 | 2020-01-30 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi. J.Struct.Biol., 211, 2020
|
|
6XYB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xyb by Molmil](/molmil-images/mine/6xyb) | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi | 分子名称: | CHLORIDE ION, IODIDE ION, MAGNESIUM ION, ... | 著者 | Roske, Y, Heinemann, U. | 登録日 | 2020-01-30 | 公開日 | 2020-06-10 | 最終更新日 | 2020-07-15 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi. J.Struct.Biol., 211, 2020
|
|
1XZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xz9 by Molmil](/molmil-images/mine/1xz9) | Structure of AF-6 PDZ domain | 分子名称: | Afadin | 著者 | Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H. | 登録日 | 2004-11-12 | 公開日 | 2005-11-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
4BEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4beg by Molmil](/molmil-images/mine/4beg) | |
2EXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2exg by Molmil](/molmil-images/mine/2exg) | Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain | 分子名称: | (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE, Afadin | 著者 | Joshi, M, Vargas, C, Boisguerin, P, Krause, G, Schade, M, Oschkinat, H. | 登録日 | 2005-11-08 | 公開日 | 2006-10-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
2FO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fo8 by Molmil](/molmil-images/mine/2fo8) | Solution structure of the Trypanosoma cruzi cysteine protease inhibitor chagasin | 分子名称: | Chagasin | 著者 | Salmon, D, do Aido-Machado, R, de Lima, A.A.P, Scharfstein, J, Oschkinat, H, Pires, J.R. | 登録日 | 2006-01-13 | 公開日 | 2006-04-04 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin J.Mol.Biol., 357, 2006
|
|
2I59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i59 by Molmil](/molmil-images/mine/2i59) | Solution structure of RGS10 | 分子名称: | Regulator of G-protein signaling 10 | 著者 | Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC) | 登録日 | 2006-08-24 | 公開日 | 2006-10-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
2M3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m3u by Molmil](/molmil-images/mine/2m3u) | |
2M3T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m3t by Molmil](/molmil-images/mine/2m3t) | |
2JNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jnu by Molmil](/molmil-images/mine/2jnu) | Solution structure of the RGS domain of human RGS14 | 分子名称: | Regulator of G-protein signaling 14 | 著者 | Dowler, E.F, Diehl, A, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G.A, Yang, X, Brockmann, C, Leidert, M, Rehbein, K, Schmieder, P, Kuhne, R, Higman, V.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | 登録日 | 2007-02-02 | 公開日 | 2007-02-27 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|