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6ZC8
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BU of 6zc8 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
分子名称: 2-[[3-chloranyl-4-[(1~{H}-indazol-3-ylcarbonylamino)methyl]phenyl]sulfonylamino]-5-methyl-benzoic acid, Segment polarity protein dishevelled homolog DVL-3
著者Roske, Y, Heinemann, U, Oschkinat, H.
登録日2020-06-10
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
6ZC4
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BU of 6zc4 by Molmil
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
分子名称: 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ...
著者Roske, Y, Heinemann, U, Oschkinat, H.
登録日2020-06-09
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
6HQC
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BU of 6hqc by Molmil
Structural investigation of the TasA anchoring protein TapA from Bacillus subtilis
分子名称: 1,2-ETHANEDIOL, TasA anchoring/assembly protein
著者Roske, Y, Heinemann, U.
登録日2018-09-24
公開日2019-10-09
最終更新日2023-04-26
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献TapA acts as specific chaperone in TasA filament formation by strand complementation.
Proc.Natl.Acad.Sci.USA, 120, 2023
1SS6
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BU of 1ss6 by Molmil
Solution structure of SEP domain from human p47
分子名称: NSFL1 cofactor p47
著者Soukenik, M, Leidert, M, Sievert, V, Buessow, K, Leitner, D, Labudde, D, Ball, L.J, Oschkinat, H.
登録日2004-03-23
公開日2004-11-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L
FEBS Lett., 576, 2004
8AIF
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BU of 8aif by Molmil
TapA acts as specific chaperone in TasA non-amyloid filament formation
分子名称: 1,2-ETHANEDIOL, NITRATE ION, YqxM protein required for localization of TasA to extracellular matrix
著者Roske, Y, Heinemann, U.
登録日2022-07-26
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献TapA acts as specific chaperone in TasA filament formation by strand complementation.
Proc.Natl.Acad.Sci.USA, 120, 2023
6XYD
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BU of 6xyd by Molmil
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi
分子名称: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
著者Roske, Y, Heinemann, U, Andrea, E.D.
登録日2020-01-30
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
J.Struct.Biol., 211, 2020
6XYB
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BU of 6xyb by Molmil
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi
分子名称: CHLORIDE ION, IODIDE ION, MAGNESIUM ION, ...
著者Roske, Y, Heinemann, U.
登録日2020-01-30
公開日2020-06-10
最終更新日2020-07-15
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
J.Struct.Biol., 211, 2020
1XZ9
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BU of 1xz9 by Molmil
Structure of AF-6 PDZ domain
分子名称: Afadin
著者Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H.
登録日2004-11-12
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angew.Chem.Int.Ed.Engl., 45, 2006
4BEG
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BU of 4beg by Molmil
Structure of Rv2140c, a phosphatidyl-ethanolamine binding protein from Mycobacterium tuberculosis in complex with sulphate
分子名称: GLYCEROL, PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN, SULFATE ION
著者Holton, S.J, Williams, M.
登録日2013-03-09
公開日2013-08-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural and Biochemical Characterization of Rv2140C, a Phosphatidylethanolamine-Binding Protein from Mycobacterium Tuberculosis.
FEBS Lett., 587, 2013
2EXG
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BU of 2exg by Molmil
Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain
分子名称: (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE, Afadin
著者Joshi, M, Vargas, C, Boisguerin, P, Krause, G, Schade, M, Oschkinat, H.
登録日2005-11-08
公開日2006-10-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angew.Chem.Int.Ed.Engl., 45, 2006
2FO8
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BU of 2fo8 by Molmil
Solution structure of the Trypanosoma cruzi cysteine protease inhibitor chagasin
分子名称: Chagasin
著者Salmon, D, do Aido-Machado, R, de Lima, A.A.P, Scharfstein, J, Oschkinat, H, Pires, J.R.
登録日2006-01-13
公開日2006-04-04
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the Trypanosoma cruzi Cysteine Protease Inhibitor Chagasin
J.Mol.Biol., 357, 2006
2I59
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BU of 2i59 by Molmil
Solution structure of RGS10
分子名称: Regulator of G-protein signaling 10
著者Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2006-08-24
公開日2006-10-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2M3U
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BU of 2m3u by Molmil
Solution-state NMR structure of cataract-related human gamma(S)-crystallin point variant G18V
分子名称: Beta-crystallin S
著者Brubaker, W.D, Martin, R.W.
登録日2013-01-25
公開日2013-11-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
Structure, 21, 2013
2M3T
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BU of 2m3t by Molmil
Solution-state NMR structure of wild-type human gamma(S)-crystallin
分子名称: Beta-crystallin S
著者Brubaker, W.D, Martin, R.W.
登録日2013-01-25
公開日2013-11-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
Structure, 21, 2013
2JNU
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BU of 2jnu by Molmil
Solution structure of the RGS domain of human RGS14
分子名称: Regulator of G-protein signaling 14
著者Dowler, E.F, Diehl, A, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G.A, Yang, X, Brockmann, C, Leidert, M, Rehbein, K, Schmieder, P, Kuhne, R, Higman, V.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2007-02-02
公開日2007-02-27
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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