8H96
| Structure of mouse SCMC core complex | 分子名称: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | 著者 | Chi, P, Ou, G, Li, J, Han, Z, Deng, D. | 登録日 | 2022-10-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H8D
| Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state) | 分子名称: | Proton-activated chloride channel | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | 登録日 | 2022-10-22 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | 主引用文献 | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state) To Be Published
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8H8F
| Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state) | 分子名称: | Proton-activated chloride channel | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | 登録日 | 2022-10-22 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state) To Be Published
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8H8E
| Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state) | 分子名称: | Proton-activated chloride channel, tRNA (75-MER)of Spodoptera frugiperda | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | 登録日 | 2022-10-22 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | 主引用文献 | Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state) To Be Published
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6KSW
| Cryo-EM structure of the human concentrative nucleoside transporter CNT3 | 分子名称: | Solute carrier family 28 member 3 | 著者 | Zhou, Y.X, Liao, L.H, Li, J.L, Xiao, Q.J, Sun, L.F, Deng, D. | 登録日 | 2019-08-26 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of the human concentrative nucleoside transporter CNT3. Plos Biol., 18, 2020
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6LTO
| cryo-EM structure of full length human Pannexin1 | 分子名称: | Pannexin-1 | 著者 | Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. | 登録日 | 2020-01-23 | 公開日 | 2020-05-13 | 最終更新日 | 2020-05-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for gating mechanism of Pannexin 1 channel. Cell Res., 30, 2020
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6LTN
| cryo-EM structure of C-terminal truncated human Pannexin1 | 分子名称: | Pannexin-1 | 著者 | Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. | 登録日 | 2020-01-23 | 公開日 | 2020-05-13 | 最終更新日 | 2020-05-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for gating mechanism of Pannexin 1 channel. Cell Res., 30, 2020
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5ZUG
| Structure of the bacterial acetate channel SatP | 分子名称: | Succinate-acetate/proton symporter SatP, nonyl beta-D-glucopyranoside | 著者 | Sun, P.C, Li, J.L, Xiao, Q.J, Guan, Z.Y, Deng, D. | 登録日 | 2018-05-07 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel. J. Biol. Chem., 293, 2018
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6KKL
| Crystal structure of Drug:Proton Antiporter-1 (DHA1) Family SotB, in the inward conformation (H115N mutant) | 分子名称: | Sugar efflux transporter, nonyl beta-D-glucopyranoside | 著者 | Xiao, Q.J, Sun, B, Zuo, Y.X, Guo, L, He, J.H, Deng, D. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | 主引用文献 | Visualizing the nonlinear changes of a drug-proton antiporter from inward-open to occluded state. Biochem.Biophys.Res.Commun., 534, 2021
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4GJP
| Crystal structure of the TAL effector dHax3 bound to dsDNA containing repetitive methyl-CpG | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), Hax3, ... | 著者 | Yan, N, Deng, D, Yan, C.Y, Yin, P, Pan, X.J, Shi, Y.G. | 登録日 | 2012-08-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of a protein complex To be Published
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4GJR
| Crystal structure of the TAL effector dHax3 bound to methylated dsDNA | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P*CP*TP*CP*(5CM)P*CP*T)-3'), Hax3 | 著者 | Yan, N, Deng, D, Yan, C.Y, Yin, P, Pan, X.J, Shi, Y.G. | 登録日 | 2012-08-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of a protein complex To be Published
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4GG4
| Crystal structure of the TAL effector dHax3 bound to specific DNA-RNA hybrid | 分子名称: | DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, RNA (5'-R(*AP*GP*AP*GP*AP*GP*AP*UP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3') | 著者 | Yin, P, Deng, D, Yan, C.Y, Pan, X.J, Yan, N, Shi, Y.G. | 登録日 | 2012-08-05 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Specific DNA-RNA hybrid recognition by TAL effectors Cell Rep, 2, 2012
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6KKI
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6KNY
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6KKK
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6KKJ
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7WN0
| Structure of PfENT1(Y190A) in complex with nanobody 19 | 分子名称: | Equilibrative nucleoside/nucleobase transporter, nanobody19 | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | 登録日 | 2022-01-17 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023
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7WN1
| Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine | 分子名称: | Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48 | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | 登録日 | 2022-01-17 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023
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7YDQ
| Structure of PfNT1(Y190A)-GFP in complex with GSK4 | 分子名称: | 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein | 著者 | Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D. | 登録日 | 2022-07-04 | 公開日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1. Nat Commun, 14, 2023
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7DLA
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7DL9
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7C83
| Crystal structure of an integral membrane steroid 5-alpha-reductase PbSRD5A | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-oxo-5-alpha-steroid 4-dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Ren, R.B, Han, Y.F, Xiao, Q.J, Deng, D. | 登録日 | 2020-05-28 | 公開日 | 2021-01-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. Nat Commun, 12, 2021
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7E26
| Structure of PfFNT in apo state | 分子名称: | Formate-nitrite transporter | 著者 | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | 登録日 | 2021-02-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism. Plos Biol., 19, 2021
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7E27
| Structure of PfFNT in complex with MMV007839 | 分子名称: | (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter | 著者 | Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J. | 登録日 | 2021-02-04 | 公開日 | 2021-08-18 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | 主引用文献 | Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism. Plos Biol., 19, 2021
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8XJ4
| Structure of prostatic acid phosphatase in human semen | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostatic acid phosphatase, alpha-D-mannopyranose, ... | 著者 | Liu, X.Z, Li, J.L, Deng, D, Wang, X. | 登録日 | 2023-12-20 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Purification, identification and Cryo-EM structure of prostatic acid phosphatase in human semen. Biochem.Biophys.Res.Commun., 702, 2024
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