5HII
 
 | | Crystal structure of glycine sarcosine N-methyltransferase (GSMT) from Methanohalophilus portucalensis (apo form) | | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase | | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | | 登録日 | 2016-01-12 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
Sci Rep, 6, 2016
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5HIM
 | | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and dimethylglycine | | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, N,N-DIMETHYLGLYCINE, ... | | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | | 登録日 | 2016-01-12 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.338 Å) | | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
Sci Rep, 6, 2016
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5HIK
 | | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine | | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | | 登録日 | 2016-01-12 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
Sci Rep, 6, 2016
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4J3N
 | | Human Topoisomerase Iibeta in complex with DNA | | 分子名称: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... | | 著者 | Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L. | | 登録日 | 2013-02-06 | | 公開日 | 2013-10-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
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6K0E
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6K0F
 | | The crystal structure of cyclopenin-bound AsqJ quinary complex | | 分子名称: | (3~{R},3'~{S})-4-methyl-3'-phenyl-spiro[1~{H}-1,4-benzodiazepine-3,2'-oxirane]-2,5-dione, 2-OXOGLUTARIC ACID, FE (III) ION, ... | | 著者 | Liao, H.J, Chan, N.L. | | 登録日 | 2019-05-06 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.634 Å) | | 主引用文献 | The crystal structure of cyclopenin-bound AsqJ quinary complex
J.Am.Chem.Soc., 2020
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6K30
 | | Binding pose 2 of 2-CF3 bound AsqJ complex | | 分子名称: | (3~{Z})-4-methyl-3-[[4-(trifluoromethyl)phenyl]methylidene]-1~{H}-1,4-benzodiazepine-2,5-dione, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | | 著者 | Liao, H.J, Chan, N.L. | | 登録日 | 2019-05-15 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.684 Å) | | 主引用文献 | Binding pose 2 of 2-CF3 bound AsqJ complex
J.Am.Chem.Soc., 2020
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6JZM
 | | The intermediate forming O-C10 bond formation in AsqJ-catalyzed epoxidation | | 分子名称: | (3~{R},3'~{S})-4-methyl-3'-phenyl-spiro[1~{H}-1,4-benzodiazepine-3,2'-oxirane]-2,5-dione, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | | 著者 | Liao, H.J, Chan, N.L. | | 登録日 | 2019-05-02 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | The intermediate forming O-C10 bond formation in AsqJ-catalyzed epoxidation
J.Am.Chem.Soc., 2020
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6KD9
 | | Binding pose 1 of 2-CF3 bound AsqJ complex | | 分子名称: | (3~{Z})-4-methyl-3-[[4-(trifluoromethyl)phenyl]methylidene]-1~{H}-1,4-benzodiazepine-2,5-dione, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | | 著者 | Liao, H.J, Chan, N.L. | | 登録日 | 2019-07-01 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Binding pose 1 of 2-CF3 bound AsqJ complex
J.Am.Chem.Soc., 2020
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1BUW
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7E38
 | | Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with yatein and succinate | | 分子名称: | (3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, (3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, Deoxypodophyllotoxin synthase, ... | | 著者 | Wu, M.-H, Chang, W.-c, Chien, T.-C, Chan, N.-L. | | 登録日 | 2021-02-08 | | 公開日 | 2021-12-15 | | 最終更新日 | 2024-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7E37
 | | Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with 2-oxoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, Deoxypodophyllotoxin synthase, FE (III) ION | | 著者 | Wu, M.-H, Lin, H.-Y, Chang, W.-c, Chien, T.-C, Chan, N.-L. | | 登録日 | 2021-02-08 | | 公開日 | 2021-12-15 | | 最終更新日 | 2024-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5Y7T
 | | Quaternary complex of AsqJ-Fe3+-2OG-D-cyclopeptin | | 分子名称: | (3R)-4-methyl-3-(phenylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione, 2-OXOGLUTARIC ACID, FE (III) ION, ... | | 著者 | Liao, H.J. | | 登録日 | 2017-08-18 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation.
Angew. Chem. Int. Ed. Engl., 57, 2018
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5Y7R
 | | Quaternary complex of AsqJ-Fe3+-2OG-cyclopeptin | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, ... | | 著者 | Liao, H.J, Lin, T.S. | | 登録日 | 2017-08-17 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Insights into the Desaturation of Cyclopeptin and its C3 Epimer Catalyzed by a non-Heme Iron Enzyme: Structural Characterization and Mechanism Elucidation.
Angew. Chem. Int. Ed. Engl., 57, 2018
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3WJA
 | | The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form | | 分子名称: | NADP-dependent malic enzyme | | 著者 | Li, S.-Y, Chen, M.-C, Yang, P.-C, Chan, N.-L, Liu, J.-H, Hung, H.-C. | | 登録日 | 2013-10-08 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.548 Å) | | 主引用文献 | Structural characteristics of the nonallosteric human cytosolic malic enzyme.
Biochim.Biophys.Acta, 1844, 2014
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1ORD
 | | CRYSTALLOGRAPHIC STRUCTURE OF A PLP-DEPENDENT ORNITHINE DECARBOXYLASE FROM LACTOBACILLUS 30A TO 3.1 ANGSTROMS RESOLUTION | | 分子名称: | ORNITHINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Hackert, M.L, Momany, C, Ernst, S, Ghosh, R. | | 登録日 | 1995-02-08 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution.
J.Mol.Biol., 252, 1995
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