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4WF5
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Crystal structure of E.Coli DsbA soaked with compound 4
分子名称: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ...
著者Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J.
登録日2014-09-12
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54, 2015
4WF4
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BU of 4wf4 by Molmil
Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4
分子名称: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, Thiol:disulfide interchange protein
著者Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J.
登録日2014-09-12
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA.
Angew.Chem.Int.Ed.Engl., 54, 2015
4LB6
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BU of 4lb6 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (tetragonal form)
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', Protein kinase containing Z-DNA binding domains
著者De Rosa, M, Zacarias, S, Athanasiadis, A.
登録日2013-06-20
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
4LB5
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BU of 4lb5 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (hexagonal form)
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', ACETATE ION, Protein kinase containing Z-DNA binding domains
著者De Rosa, M, Zacarias, S, Athanasiadis, A.
登録日2013-06-20
公開日2013-09-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
5VMN
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BU of 5vmn by Molmil
Crystal structure of grouper iridovirus GIV66
分子名称: 1,2-ETHANEDIOL, Bak protein, NITRATE ION
著者Banjara, S, Kvansakul, M.
登録日2017-04-27
公開日2018-03-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018
5VMO
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BU of 5vmo by Molmil
Crystal structure of grouper iridovirus GIV66:Bim complex
分子名称: 1,2-ETHANEDIOL, Bak protein, Bcl-2 interacting mediator of cell death, ...
著者Banjara, S, Kvansakul, M.
登録日2017-04-28
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018
6FBX
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BU of 6fbx by Molmil
Crystal Structure of a Zebra-fish pro-survival protein NRZ:Bad BH3 complex
分子名称: BCL2-antagonist of cell death, BCL2-like 10
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2017-12-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.639 Å)
主引用文献A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018
5AJJ
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BU of 5ajj by Molmil
Crystal structure of variola virus virulence factor F1L in complex with human Bid BH3 domain
分子名称: ACETATE ION, BH3-INTERACTING DOMAIN DEATH AGONIST, GLYCEROL, ...
著者Kvansakul, M, Colman, P.M.
登録日2015-02-25
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
5AJK
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BU of 5ajk by Molmil
Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain
分子名称: ACETATE ION, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, CHLORIDE ION, ...
著者Kvansakul, M, Colman, P.M.
登録日2015-02-25
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
6H1N
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BU of 6h1n by Molmil
Crystal Structure of a Zebra-fish pro-survival protein NRZ-apo
分子名称: ACETATE ION, BCL2-like 10 (Apoptosis facilitator), SULFATE ION
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2018-07-12
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018
6OWJ
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BU of 6owj by Molmil
Zn-mediated polymerization of human SFPQ
分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION
著者Lee, M.
登録日2019-05-10
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ.
Nucleic Acids Res., 48, 2020
4UF1
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BU of 4uf1 by Molmil
Deerpox virus DPV022 in complex with Bak BH3
分子名称: Antiapoptotic membrane protein, Bcl-2 homologous antagonist/killer, SULFATE ION
著者Burton, D.R, Kvansakul, M.
登録日2014-12-23
公開日2015-08-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF2
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BU of 4uf2 by Molmil
Deerpox virus DPV022 in complex with Bax BH3
分子名称: Antiapoptotic membrane protein, Apoptosis regulator BAX
著者Burton, D.R, Kvansakul, M.
登録日2014-12-23
公開日2015-08-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
4UF3
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BU of 4uf3 by Molmil
Deerpox virus DPV022 in complex with Bim BH3
分子名称: Antiapoptotic membrane protein, Bcl-2-like protein 11
著者Burton, D.R, Kvansakul, M.
登録日2014-12-23
公開日2015-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis.
Acta Crystallogr.,Sect.D, 71, 2015
6CS9
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BU of 6cs9 by Molmil
Crystal structure of human beta-defensin 2 in complex with PIP2
分子名称: Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Jarva, M, Phan, K, Lay, F.T, Humble, C, Hulett, M, Kvansakul, M.
登録日2018-03-20
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
Sci Adv, 4, 2018
6BQX
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BU of 6bqx by Molmil
Crystal structure of Escherichia coli DsbA in complex with N-methyl-1-(4-phenoxyphenyl)methanamine
分子名称: N-methyl-1-(4-phenoxyphenyl)methanamine, Thiol:disulfide interchange protein DsbA
著者Heras, B, Totsika, M, Paxman, J.J, Wang, G, Scanlon, M.J.
登録日2017-11-29
公開日2017-12-27
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.
Antioxid. Redox Signal., 29, 2018
6NCQ
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BU of 6ncq by Molmil
The dimerization domain of human SFPQ in space group C2221
分子名称: Splicing factor, proline- and glutamine-rich
著者Lee, M.
登録日2018-12-12
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ.
Acta Crystallogr.,Sect.F, 75, 2019
7S1C
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BU of 7s1c by Molmil
Crystal structure of E.coli DsbA in complex with compound MIPS-0001897 (compound 1)
分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-3-ylphenyl)methanamine
著者Heras, B, Scanlon, M.J, Martin, J.L, Sharma, P.
登録日2021-09-02
公開日2023-02-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates
Chemrxiv, 2022
8B87
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BU of 8b87 by Molmil
Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
分子名称: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, Protein E6, ...
著者Stewart, B.Z, Kvansakul, M.
登録日2022-10-04
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
8B9T
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BU of 8b9t by Molmil
Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, Protein E6, ...
著者Stewart, B.Z, Kvansakul, M.
登録日2022-10-07
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
8B82
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BU of 8b82 by Molmil
Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
分子名称: CHLORIDE ION, Protein E6, Protein scribble homolog
著者Stewart, B.Z, Kvansakul, M.
登録日2022-10-04
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
8B8O
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BU of 8b8o by Molmil
Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
分子名称: 1,2-ETHANEDIOL, Protein E6, Protein scribble homolog
著者Stewart, B.Z, Kvansakul, M.
登録日2022-10-04
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
8BIA
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BU of 8bia by Molmil
Crystal structure of Scribble PDZ1 with PTHR
分子名称: PHOSPHATE ION, Parathyroid hormone/parathyroid hormone-related peptide receptor, Protein scribble homolog
著者Stewart, B.Z, Kvansakul, M.
登録日2022-11-02
公開日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
8BJ0
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BU of 8bj0 by Molmil
Crystal structure of Scribble PDZ1 with PTHR
分子名称: CHLORIDE ION, Parathyroid hormone/parathyroid hormone-related peptide receptor, Protein scribble homolog
著者Stewart, B.Z, Kvansakul, M.
登録日2022-11-03
公開日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
5TZQ
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BU of 5tzq by Molmil
Crystal Structure of FPV039:Bmf BH3 complex
分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bcl-2-modifying factor
著者Anasir, M.I, Kvansakul, M.
登録日2016-11-22
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
J. Biol. Chem., 292, 2017

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