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7SSJ
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BU of 7ssj by Molmil
Crystal structure of the DesK-DesR complex in the phosphatase state
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Trajtenberg, F, Buschiazzo, A.
登録日2021-11-11
公開日2022-11-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
Sci.Signal., 16, 2023
8EBF
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BU of 8ebf by Molmil
C-terminal (TPR) domain of LIC11990 from Leptospira interrogans
分子名称: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL
著者Larrieux, N, Buschiazzo, A.
登録日2022-08-31
公開日2022-09-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990)
To Be Published
4DVH
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Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase
分子名称: FE (III) ION, Superoxide dismutase
著者Larrieux, N, Buschiazzo, A.
登録日2012-02-23
公開日2013-03-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B: DISPARATE SUSCEPTIBILITIES DUE TO THE REPAIR OF TYR35 RADICAL BY CYS83 IN Fe-SODB THROUGH INTRAMOLECULAR ELECTRON TRANSFER.
J.Biol.Chem., 289, 2014
5CEE
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BU of 5cee by Molmil
Malic enzyme from Candidatus Phytoplasma AYWB in complex with NAD and Mg2+
分子名称: MAGNESIUM ION, NAD-dependent malic enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Alvarez, C.E, Trajtenberg, F, Larrieux, N, Saigo, M, Mussi, M.A, Andreo, C.S, Drincovich, M.F, Buschiazzo, A.
登録日2015-07-06
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme.
Acta Crystallogr D Struct Biol, 74, 2018
6XQK
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BU of 6xqk by Molmil
Crystal structure of the D/D domain of PKA from S. cerevisiae
分子名称: CHLORIDE ION, GLYCEROL, cAMP-dependent protein kinase regulatory subunit
著者Larrieux, N, Gonzalez Bardeci, N, Trajtenberg, F, Buschiazzo, A.
登録日2020-07-09
公開日2021-04-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization.
J.Struct.Biol., 213, 2021
1N1Y
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BU of 1n1y by Molmil
Trypanosoma rangeli sialidase in complex with sialic acid
分子名称: N-acetyl-alpha-neuraminic acid, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-21
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1T
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BU of 1n1t by Molmil
Trypanosoma rangeli sialidase in complex with DANA at 1.6 A
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-20
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1S
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BU of 1n1s by Molmil
Trypanosoma rangeli sialidase
分子名称: SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-20
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
1N1V
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Trypanosoma rangeli sialidase in complex with DANA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, SULFATE ION, Sialidase
著者Amaya, M.F, Buschiazzo, A, Nguyen, T, Alzari, P.M.
登録日2002-10-21
公開日2003-01-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase
J.Mol.Biol., 325, 2003
7SSI
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BU of 7ssi by Molmil
CRYSTAL STRUCTURE OF THE DESK:DESR-Q10A COMPLEX IN THE PHOSPHOTRANSFER STATE
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Sensor histidine kinase DesK, ...
著者Trajtenberg, F, Buschiazzo, A.
登録日2021-11-11
公開日2022-11-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
Sci.Signal., 16, 2023
6NQY
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BU of 6nqy by Molmil
Flagellar protein FcpA from Leptospira biflexa / ab-centered monoclinic form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Flagellar coiling protein A, ...
著者Mechaly, A, Larrieux, N, Trajtenberg, F, Buschiazzo, A.
登録日2019-01-22
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete.
Elife, 9, 2020
6NQX
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Flagellar protein FcpA from Leptospira biflexa / primitive monoclinic form
分子名称: Flagellar coiling protein A, GLYCEROL
著者Mechaly, A, Larrieux, N, Trajtenberg, F, Buschiazzo, A.
登録日2019-01-22
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete
Elife, 9, 2020
2AH2
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BU of 2ah2 by Molmil
Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, GLYCEROL, ...
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2005-07-27
公開日2005-08-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Structure, 12, 2004
6NQW
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BU of 6nqw by Molmil
Flagellar protein FcpA from Leptospira biflexa - hexagonal form
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Flagellar coiling protein A, GLYCEROL, ...
著者San Martin, F, Trajtenberg, F, Larrieux, N, Buschiazzo, A.
登録日2019-01-22
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete
Elife, 9, 2020
2GEJ
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BU of 2gej by Molmil
Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man
分子名称: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA)
著者Guerin, M.E, Buschiazzo, A, Kordulakova, J, Jackson, M, Alzari, P.M.
登録日2006-03-20
公開日2007-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
J.Biol.Chem., 282, 2007
2GEK
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Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA)
著者Guerin, M.E, Buschiazzo, A, Kordulakova, J, Jackson, M, Alzari, P.M.
登録日2006-03-20
公開日2007-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
J.Biol.Chem., 282, 2007
1S0I
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BU of 1s0i by Molmil
Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex)
分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2003-12-31
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
6O6P
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BU of 6o6p by Molmil
Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA
分子名称: DNA-forward, DNA-reverse, TetR family transcriptional regulator
著者Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A.
登録日2019-03-07
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.851 Å)
主引用文献Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11, 2020
1S0J
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Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex)
分子名称: 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID, trans-sialidase
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2003-12-31
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase.
Structure, 12, 2004
2UYQ
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Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine
分子名称: HYPOTHETICAL PROTEIN ML2640, S-ADENOSYLMETHIONINE
著者Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M.
登録日2007-04-11
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria.
Protein Sci., 16, 2007
2UYO
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Crystal structure of ML2640c from Mycobacterium leprae in an hexagonal crystal form
分子名称: HYPOTHETICAL PROTEIN ML2640
著者Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M.
登録日2007-04-11
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria.
Protein Sci., 16, 2007
6D23
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GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI
分子名称: CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ...
著者Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A.
登録日2018-04-12
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
6D24
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Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P
分子名称: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A.
登録日2018-04-12
公開日2018-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
2V7S
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BU of 2v7s by Molmil
Crystal structure of the putative lipoprotein LppA from Mycobacterium tuberculosis
分子名称: GLYCEROL, PROBABLE CONSERVED LIPOPROTEIN LPPA
著者Grana, M, Miras, I, Haouz, A, Winter, N, Buschiazzo, A, Bellinzoni, M, Alzari, P.M.
登録日2007-08-01
公開日2008-08-26
最終更新日2011-09-28
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structure of Mycobacterium Tuberculosis Lppa, a Lipoprotein Confined to Pathogenic Mycobacteria.
Proteins, 78, 2010
2WAM
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Crystal structure of Mycobacterium tuberculosis unknown function protein Rv2714
分子名称: CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN, GLYCEROL
著者Bellinzoni, M, Grana, M, Buschiazzo, A, Miras, I, Haouz, A, Alzari, P.M.
登録日2009-02-09
公開日2009-10-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Mycobacterium Tuberculosis Rv2714, a Representative of a Duplicated Gene Family in Actinobacteria.
Acta Crystallogr.,Sect.F, 65, 2009

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