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1OBQ
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Apocrustacyanin C1 crystals grown in space and earth using vapour diffusion geometry
分子名称: CRUSTACYANIN C1 SUBUNIT
著者Habash, J, Boggon, T.J, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
登録日2003-01-31
公開日2003-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Apocrustacyanin C(1) Crystals Grown in Space and on Earth Using Vapour-Diffusion Geometry: Protein Structure Refinements and Electron-Density Map Comparisons
Acta Crystallogr.,Sect.D, 59, 2003
4Y5O
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CCM2 HHD in complex with MEKK3 NPB1
分子名称: Malcavernin, Mitogen-activated protein kinase kinase kinase 3
著者Fisher, O.S, Boggon, T.J.
登録日2015-02-11
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
Nat Commun, 6, 2015
7S47
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Integrin beta5(743-774)-linker-PAK4cat(D440N/S474E)
分子名称: Integrin beta-5, Isoform 2 of Serine/threonine-protein kinase PAK 4 chimera, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Ha, B.H, Boggon, T.J.
登録日2021-09-08
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)
Commun Biol, 5, 2022
7S48
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PAK4cat in complex with Integrin beta5 760-770 peptide
分子名称: Integrin beta-5, Serine/threonine-protein kinase PAK 4
著者Ha, B.H, Boggon, T.J.
登録日2021-09-08
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)
Commun Biol, 5, 2022
7S46
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PAK4cat (D440N/S474E) in complex with Integrin beta5 760-770 peptide
分子名称: Integrin beta-5, Isoform 2 of Serine/threonine-protein kinase PAK 4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Ha, B.H, Boggon, T.J.
登録日2021-09-08
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)
Commun Biol, 5, 2022
5D68
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Crystal structure of KRIT1 ARD-FERM
分子名称: Krev interaction trapped protein 1
著者Zhang, R, Li, X, Boggon, T.J.
登録日2015-08-11
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
3IXE
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BU of 3ixe by Molmil
Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase
分子名称: Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 2, ZINC ION
著者Chiswell, B.P, Stiegler, A.L, Boggon, T.J, Calderwood, D.A.
登録日2009-09-03
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase.
J.Struct.Biol., 170, 2010
1BWI
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BU of 1bwi by Molmil
THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
分子名称: PROTEIN (LYSOZYME)
著者Dong, J, Boggon, T.J, Chayen, N.E, Raftery, J, Bi, R.C.
登録日1998-09-24
公開日1998-09-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BVX
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THE 1.8 A STRUCTURE OF GEL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
分子名称: PROTEIN (LYSOZYME)
著者Dong, J, Boggon, T.J, Chayen, N.E, Raftery, J, Bi, R.C, Helliwell, J.R.
登録日1998-09-18
公開日1998-09-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BWJ
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THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
分子名称: PROTEIN (LYSOZYME)
著者Dong, J, Boggon, T.J, Chayen, N.E, Raftery, J, Bi, R.C.
登録日1998-09-18
公開日1998-09-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BWH
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BU of 1bwh by Molmil
THE 1.8 A STRUCTURE OF GROUND CONTROL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME
分子名称: PROTEIN (LYSOZYME)
著者Dong, J, Boggon, T.J, Chayen, N.E, Raftery, J, Bi, R.C.
登録日1998-09-24
公開日1998-09-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound-solvent structures for microgravity-, ground control-, gel- and microbatch-grown hen egg-white lysozyme crystals at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
3KXX
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BU of 3kxx by Molmil
Structure of the mutant Fibroblast Growth Factor receptor 1
分子名称: Basic fibroblast growth factor receptor 1
著者Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2009-12-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KY2
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BU of 3ky2 by Molmil
Crystal structure of Fibroblast Growth Factor Receptor 1 kinase domain
分子名称: Basic fibroblast growth factor receptor 1, SULFATE ION
著者Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2009-12-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3L8J
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Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity
分子名称: Programmed cell death protein 10
著者Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J.
登録日2009-12-31
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
J.Biol.Chem., 285, 2010
3L8I
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Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity
分子名称: Programmed cell death protein 10
著者Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J.
登録日2009-12-31
公開日2010-05-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
J.Biol.Chem., 285, 2010
6WAY
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BU of 6way by Molmil
C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 35
著者Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J.
登録日2020-03-26
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
6WAX
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C-terminal SH2 domain of p120RasGAP
分子名称: 1,2-ETHANEDIOL, Ras GTPase-activating protein 1, SULFATE ION
著者Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J.
登録日2020-03-26
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
6WLY
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BU of 6wly by Molmil
PAK4 kinase domain in complex with LIMK1 Thr508 substrate peptide
分子名称: LIM Kinase 1 peptide, Serine/threonine-protein kinase PAK 4
著者Chetty, A.K, Ha, B.H, Boggon, T.J.
登録日2020-04-20
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Recognition of physiological phosphorylation sites by p21-activated kinase 4.
J.Struct.Biol., 211, 2020
6WLX
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PAK4 kinase domain in complex with beta-catenin Ser675 substrate peptide
分子名称: Catenin beta-1, Serine/threonine-protein kinase PAK 4
著者Chetty, A.K, Ha, B.H, Boggon, T.J.
登録日2020-04-20
公開日2020-06-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of physiological phosphorylation sites by p21-activated kinase 4.
J.Struct.Biol., 211, 2020
3RQG
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Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4
分子名称: Paxillin LD4 peptide, Programmed cell death protein 10
著者Li, X, Zhang, R, Boggon, T.J.
登録日2011-04-28
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem., 286, 2011
3RQF
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Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2
分子名称: Paxillin LD2 peptide, Programmed cell death protein 10
著者Li, X, Zhang, R, Boggon, T.J.
登録日2011-04-28
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem., 286, 2011
3RQE
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Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1
分子名称: Paxillin LD1 peptide, Programmed cell death protein 10
著者Li, X, Zhang, R, Boggon, T.J.
登録日2011-04-28
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem., 286, 2011
3SBE
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Crystal structure of RAC1 P29S mutant
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1
著者Ha, B.H, Boggon, T.J.
登録日2011-06-03
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
3SBD
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Crystal structure of RAC1 P29S mutant
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1
著者Ha, B.H, Boggon, T.J.
登録日2011-06-03
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
2ITT
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Crystal structure of EGFR kinase domain L858R mutation in complex with AEE788
分子名称: 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE, EPIDERMAL GROWTH FACTOR RECEPTOR
著者Yun, C.-H, Boggon, T.J, Li, Y, Woo, S, Greulich, H, Meyerson, M, Eck, M.J.
登録日2006-05-25
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity
Cancer Cell, 11, 2007

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