3QSY
 
 | | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea | | 分子名称: | METHIONINE, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 subunit alpha, ... | | 著者 | Nikonov, O.S, Stolboushkina, E.A, Zelinskaya, N.V, Nikulin, A.D, Garber, M.B, Nikonov, S.V. | | 登録日 | 2011-02-22 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of the archaeal translation initiation factor 2 in complex with a GTP analogue and Met-tRNAf(Met.)
J.Mol.Biol., 425, 2013
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8CSG
 | | Human PRMT5:MEP50 structure with Fragment 1 and MTA Bound | | 分子名称: | 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 6-bromo-1H-pyrrolo[3,2-b]pyridin-5-amine, ... | | 著者 | Gunn, R.J, Lawson, J.D, Smith, C.R. | | 登録日 | 2022-05-12 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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8CTB
 | | Human PRMT5:MEP50 structure with Fragment 3 and MTA Bound | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, 7-chloro-1-methyl-1H-benzimidazol-2-amine, Methylosome protein 50, ... | | 著者 | Gunn, R.J, Lawson, J.D, Smith, C.R. | | 登録日 | 2022-05-13 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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6I5M
 | | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion | | 分子名称: | FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kravchenko, O, Nikonov, O, Gabdulkhakov, A, Stolboushkina, E, Arkhipova, V, Garber, M, Nikonov, S. | | 登録日 | 2018-11-13 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome.
Acta Crystallogr D Struct Biol, 75, 2019
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8AFA
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6R8T
 | | Crystal structure of aIF2gamma subunit I181T from archaeon Sulfolobus solfataricus complexed with GDPCP | | 分子名称: | FORMIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Kravchenko, O, Arkhipova, V, Gabdulkhakov, A, Stolboushkina, E, Nikonov, O, Garber, M, Nikonov, S. | | 登録日 | 2019-04-02 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of aIF2gamma subunit I181T from archaeon Sulfolobus solfataricus complexed with GDPCP
To Be Published
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6R8S
 | | Crystal structure of aIF2gamma subunit I181K from archaeon Sulfolobus solfataricus complexed with GDPCP | | 分子名称: | FORMIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Kravchenko, O, Arkhipova, V, Gabdulkhakov, A, Stolboushkina, E, Nikonov, O, Garber, M, Nikonov, S. | | 登録日 | 2019-04-02 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Crystal structure of aIF2gamma subunit I181K from archaeon Sulfolobus solfataricus complexed with GDPCP
To Be Published
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