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2O78
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BU of 2o78 by Molmil
Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant) complexed with cinnamic acid
分子名称: PHENYLETHYLENECARBOXYLIC ACID, Putative histidine ammonia-lyase
著者Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P.
登録日2006-12-10
公開日2007-01-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
2NYF
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BU of 2nyf by Molmil
Crystal structure of phenylalanine ammonia-lyase from Nostoc punctiforme
分子名称: Nostoc punctiforme phenylalanine ammonia lyase
著者Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S.
登録日2006-11-20
公開日2007-02-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
Biochemistry, 46, 2007
2O7D
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BU of 2o7d by Molmil
Tyrosine ammonia-lyase from Rhodobacter sphaeroides, complexed with caffeate
分子名称: CAFFEIC ACID, Putative histidine ammonia-lyase
著者Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P.
登録日2006-12-10
公開日2007-01-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
2NYN
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BU of 2nyn by Molmil
Crystal structure of phenylalanine ammonia-lyase from Anabaena variabilis
分子名称: Phenylalanine/histidine ammonia-lyase
著者Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S.
登録日2006-11-21
公開日2007-02-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
Biochemistry, 46, 2007
4XLO
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BU of 4xlo by Molmil
Crystal Structure of EncM (crystallized with 4 mM NADPH)
分子名称: FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
著者Teufel, R.
登録日2015-01-13
公開日2015-01-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
1SE6
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BU of 1se6 by Molmil
Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-02-16
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
7JPJ
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BU of 7jpj by Molmil
Crystal Structure of the essential dimeric LYSA from Phaeodactylum tricornutum
分子名称: D-LYSINE, Diaminopimelate decarboxylase, SULFATE ION
著者Fedorov, E, Belinski, V.A, Brunson, J.K, Almo, S.C, Dupont, C.L, Ghosh, A.
登録日2020-08-08
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献The Phaeodactylum tricornutum diaminopimelate decarboxylase was acquired via horizontal gene transfer from bacteria and displays substrate promiscuity
Biorxiv, 2020
8TWN
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BU of 8twn by Molmil
Crystal structure of nitrile synthase AetD with substrate bound
分子名称: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, D-MALATE
著者Ye, N, Drennan, C.L.
登録日2023-08-21
公開日2024-08-28
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile.
Nat.Chem., 2024
8TWT
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BU of 8twt by Molmil
Crystal structure of nitrile synthase AetD with substrate bound and cofactor partially assembled
分子名称: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, D-MALATE, ...
著者Ye, N, Drennan, C.L.
登録日2023-08-21
公開日2024-08-28
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile.
Nat.Chem., 2024
8TWW
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BU of 8tww by Molmil
Crystal structure of nitrile synthase AetD with substrate bound and cofactor fully assembled
分子名称: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, FE (III) ION
著者Ye, N, Drennan, C.L.
登録日2023-08-21
公開日2024-08-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile.
Nat.Chem., 2024
6CY8
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BU of 6cy8 by Molmil
Crystal structure of FAD-dependent dehydrogenase
分子名称: 4'-PHOSPHOPANTETHEINE, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ...
著者Agarwal, V.
登録日2018-04-05
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.729 Å)
主引用文献Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
Biochemistry, 58, 2019
6CXT
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BU of 6cxt by Molmil
Crystal structure of FAD-dependent dehydrogenase
分子名称: 1,2-ETHANEDIOL, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ...
著者Agarwal, V.
登録日2018-04-04
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
Biochemistry, 58, 2019
4HNP
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BU of 4hnp by Molmil
Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin analogue VNK1
分子名称: N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylhept-1-en-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, ...
著者Trivella, D.B.B, Stein, M, Groll, M.
登録日2012-10-20
公開日2014-01-29
最終更新日2014-07-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRC
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BU of 4hrc by Molmil
Crystal structure of yeast 20S proteasome in complex with epoxyketone carmaphycin analogue 3
分子名称: N-hexanoyl-L-valyl-N~1~-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, Proteasome component C11, ...
著者Trivella, D.B.B, Stein, M, Groll, M.
登録日2012-10-27
公開日2014-01-29
最終更新日2014-07-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRD
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BU of 4hrd by Molmil
Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A
分子名称: N-[(2S)-1-({(2S)-1-{[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]amino}-4-[(R)-methylsulfinyl]-1-oxobutan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]hexanamide, Proteasome component C1, Proteasome component C11, ...
著者Trivella, D.B.B, Stein, M, Groll, M.
登録日2012-10-27
公開日2014-01-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4LTC
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BU of 4ltc by Molmil
Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6
分子名称: N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Stein, M, Trivella, D.B.B, Groll, M.
登録日2013-07-23
公開日2014-07-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
1T93
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BU of 1t93 by Molmil
Evidence for Multiple Substrate Recognition and Molecular Mechanism of C-C reaction by Cytochrome P450 CYP158A2 from Streptomyces Coelicolor A3(2)
分子名称: FLAVIOLIN, PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450
著者Zhao, B, Sundaramoorthy, M, Waterman, M.R.
登録日2004-05-14
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
2WR8
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BU of 2wr8 by Molmil
Structure of Pyrococcus horikoshii SAM hydroxide adenosyltransferase in complex with SAH
分子名称: PUTATIVE UNCHARACTERIZED PROTEIN PH0463, S-ADENOSYL-L-HOMOCYSTEINE
著者McMahon, S.A, Deng, H, O'Hagan, D, Johnson, K.A, Naismith, J.H.
登録日2009-08-31
公開日2009-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Mechanistic Insights Into Water Activation in Sam Hydroxide Adenosyltransferase (Duf-62).
Chembiochem, 10, 2009
2D09
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BU of 2d09 by Molmil
A Role for Active Site Water Molecules and Hydroxyl Groups of Substrate for Oxygen Activation in Cytochrome P450 158A2
分子名称: FLAVIOLIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhao, B, Waterman, M.R.
登録日2005-07-30
公開日2005-10-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer
J.Biol.Chem., 280, 2005
2Q6L
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BU of 2q6l by Molmil
SalL double mutant Y70T/G131S with CLDA and L-MET
分子名称: 5'-CHLORO-5'-DEOXYADENOSINE, Hypothetical protein, METHIONINE
著者Pojer, F, Noel, J.P.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6O
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BU of 2q6o by Molmil
SalL-Y70T with SAM and Cl
分子名称: CHLORIDE ION, Hypothetical Protein, S-ADENOSYLMETHIONINE
著者Noel, J.P, Pojer, F.
登録日2007-06-05
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6I
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BU of 2q6i by Molmil
salL with ClDA and LMet
分子名称: 5'-CHLORO-5'-DEOXYADENOSINE, DI(HYDROXYETHYL)ETHER, Hypothetical protein, ...
著者Noel, J.P, Pojer, F.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6K
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SalL with adenosine
分子名称: ADENOSINE, DI(HYDROXYETHYL)ETHER, chlorinase
著者Pojer, F, Noel, J.P.
登録日2007-06-05
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
1S1F
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BU of 1s1f by Molmil
Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 4-PHENYL-1H-IMIDAZOLE, GLYCEROL, MALONIC ACID, ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-01-06
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J.Biol.Chem., 280, 2005
6FOQ
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BU of 6foq by Molmil
The crystal structure of EncM complexed with dioxygen under 15 bar of oxygen pressure.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, Putative FAD-dependent oxygenase EncM
著者Saleem-Batcha, R, Teufel, R.
登録日2018-02-08
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.386 Å)
主引用文献Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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