3LBH
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![BU of 3lbh by Molmil](/molmil-images/mine/3lbh) | Ras soaked in Calcium Acetate | 分子名称: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | 著者 | Holzapfel, G, Buhrman, G, Mattos, C. | 登録日 | 2010-01-08 | 公開日 | 2010-03-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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6DZH
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![BU of 6dzh by Molmil](/molmil-images/mine/6dzh) | HRAS G13D bound to GDP (H13GDP) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GLYCEROL, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-04 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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6E6F
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![BU of 6e6f by Molmil](/molmil-images/mine/6e6f) | KRAS G13D bound to GppNHp (K13GNP) | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-24 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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6E6G
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![BU of 6e6g by Molmil](/molmil-images/mine/6e6g) | KRAS G13D bound to GDP (K13GDP) | 分子名称: | CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-24 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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8FG3
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![BU of 8fg3 by Molmil](/molmil-images/mine/8fg3) | HRAS R97L Crystal Form 2 | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Fetics, S, Johnson, C.W, Mattos, C. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
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8FG4
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![BU of 8fg4 by Molmil](/molmil-images/mine/8fg4) | HRAS R97L Crystal Form 1 | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Fetics, S, Johnson, C.W, Mattos, C. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
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4RSG
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![BU of 4rsg by Molmil](/molmil-images/mine/4rsg) | Neutron crystal structure of Ras bound to the GTP analogue GppNHp | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Knihtila, R.R, Holzapfel, G, Weiss, K.L, Meilleur, F, Mattos, C. | 登録日 | 2014-11-07 | 公開日 | 2015-11-04 | 最終更新日 | 2024-02-28 | 実験手法 | NEUTRON DIFFRACTION (1.907 Å) | 主引用文献 | Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP gamma-Phosphate. J.Biol.Chem., 290, 2015
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6UNT
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![BU of 6unt by Molmil](/molmil-images/mine/6unt) | Barrier-to-autointegration factor soaked in DMSO: 1 of 14 in MSCS set | 分子名称: | Barrier-to-autointegration factor, ETHANOL | 著者 | Agarwal, S, Smith, M, De La Rosa, I, Kliment, A.V, Swartz, P, Segura-Totten, M, Mattos, C. | 登録日 | 2019-10-13 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor. Acta Crystallogr D Struct Biol, 76, 2020
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4XVQ
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![BU of 4xvq by Molmil](/molmil-images/mine/4xvq) | H-Ras Y137E | 分子名称: | GLYCEROL, GTPase HRas, MAGNESIUM ION, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2015-01-27 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.887 Å) | 主引用文献 | Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb J., 29, 2015
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4XVR
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![BU of 4xvr by Molmil](/molmil-images/mine/4xvr) | H-Ras Y137F | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2015-01-27 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb J., 29, 2015
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2P1H
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![BU of 2p1h by Molmil](/molmil-images/mine/2p1h) | Rapid Folding and Unfolding of Apaf-1 CARD | 分子名称: | Apoptotic protease-activating factor 1, ZINC ION | 著者 | Milam, S.L, Nicely, N.I, Feeney, B, Mattos, C, Clark, A.C. | 登録日 | 2007-03-05 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Rapid Folding and Unfolding of Apaf-1 CARD. J.Mol.Biol., 369, 2007
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2RGD
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![BU of 2rgd by Molmil](/molmil-images/mine/2rgd) | Crystal structure of H-RasQ61L-GppNHp | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGE
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![BU of 2rge by Molmil](/molmil-images/mine/2rge) | Crystal structure of H-Ras-GppNHp | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGB
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![BU of 2rgb by Molmil](/molmil-images/mine/2rgb) | Crystal structure of H-RasQ61K-GppNHp | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGG
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![BU of 2rgg by Molmil](/molmil-images/mine/2rgg) | Crystal structure of H-RasQ61I-GppNHp, trigonal crystal form | 分子名称: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGC
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![BU of 2rgc by Molmil](/molmil-images/mine/2rgc) | Crystal structure of H-RasQ61V-GppNHp | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGA
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![BU of 2rga by Molmil](/molmil-images/mine/2rga) | Crystal structure of H-RasQ61I-GppNHp | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Buhrman, G, Wink, G, Mattos, C. | 登録日 | 2007-10-03 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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6E6P
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![BU of 6e6p by Molmil](/molmil-images/mine/6e6p) | HRAS G13D bound to GppNHp (Ha,b,c13GNP) | 分子名称: | CALCIUM ION, GLYCEROL, GTPase HRas, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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6E6C
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![BU of 6e6c by Molmil](/molmil-images/mine/6e6c) | HRAS G13D bound to GppNHp (H13GNP) | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-24 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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6E6H
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![BU of 6e6h by Molmil](/molmil-images/mine/6e6h) | NRAS G13D bound to GppNHp (N13GNP) | 分子名称: | GTPase NRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2018-07-24 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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7JHP
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![BU of 7jhp by Molmil](/molmil-images/mine/7jhp) | |
1U8Y
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![BU of 1u8y by Molmil](/molmil-images/mine/1u8y) | CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A | 著者 | Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C. | 登録日 | 2004-08-09 | 公開日 | 2004-11-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap Structure, 12, 2004
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1U90
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![BU of 1u90 by Molmil](/molmil-images/mine/1u90) | Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A | 著者 | Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C. | 登録日 | 2004-08-09 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap Structure, 12, 2004
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1U8Z
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![BU of 1u8z by Molmil](/molmil-images/mine/1u8z) | Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A | 著者 | Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C. | 登録日 | 2004-08-09 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap Structure, 12, 2004
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5UHV
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![BU of 5uhv by Molmil](/molmil-images/mine/5uhv) | wild-type NRas bound to GppNHp | 分子名称: | GLYCEROL, GTPase NRas, MAGNESIUM ION, ... | 著者 | Reid, D, Johnson, C, Salter, S, Mattos, C. | 登録日 | 2017-01-12 | 公開日 | 2017-06-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | 主引用文献 | The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects. J. Biol. Chem., 292, 2017
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