6E6C

HRAS G13D bound to GppNHp (H13GNP)

Summary for 6E6C

Entry DOI	10.2210/pdb6e6c/pdb
Related	6DZH 6E6F 6E6G 6E6H 6E6P
Descriptor	GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywords	oncogene, ras, p21, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	19519.81
Authors	Johnson, C.W.,Mattos, C. (deposition date: 2018-07-24, release date: 2019-07-31, Last modification date: 2023-10-11)
Primary citation	Johnson, C.W.,Lin, Y.J.,Reid, D.,Parker, J.,Pavlopoulos, S.,Dischinger, P.,Graveel, C.,Aguirre, A.J.,Steensma, M.,Haigis, K.M.,Mattos, C. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28:1538-1550.e7, 2019 Cited by PubMed: 31390567 DOI: 10.1016/j.celrep.2019.07.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation