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4TSX
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BU of 4tsx by Molmil
HIV-1 Integrase Catalytic Core Domain Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2014-06-19
公開日2014-12-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The mechanism of H171T resistance reveals the importance of N -protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
Retrovirology, 11, 2014
1XZY
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BU of 1xzy by Molmil
Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP)
分子名称: Alpha-hemoglobin stabilizing protein
著者Gell, D.A, Feng, L, Zhou, S, Kong, Y, Lee, C, Weiss, M.J, Shi, Y, Mackay, J.P.
登録日2004-11-12
公開日2004-12-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin
Cell(Cambridge,Mass.), 119, 2004
5KGW
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BU of 5kgw by Molmil
HIV1 catalytic core domain in complex with inhibitor: (2~{S})-2-[3-(3,4-dihydro-2~{H}-chromen-6-yl)-1-methyl-indol-2-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid
分子名称: (2S)-tert-butoxy[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-1-methyl-1H-indol-2-yl]acetic acid, Integrase, SULFATE ION
著者Feng, L, Kobe, M, Kvaratskhelia, M.
登録日2016-06-13
公開日2016-10-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Indole-based allosteric inhibitors of HIV-1 integrase.
Bioorg.Med.Chem.Lett., 26, 2016
5KGX
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BU of 5kgx by Molmil
HIV1 catalytic core domain in complex with an inhibitor (2~{S})-2-[3-(3,4-dihydro-2~{H}-chromen-6-yl)-1-methyl-indol-2-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid
分子名称: (2S)-tert-butoxy[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-1-methyl-1H-indol-2-yl]acetic acid, Integrase, SULFATE ION
著者Feng, L, Kobe, M, Kvaratskhelia, M.
登録日2016-06-13
公開日2016-10-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Indole-based allosteric inhibitors of HIV-1 integrase.
Bioorg.Med.Chem.Lett., 26, 2016
4DMN
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BU of 4dmn by Molmil
HIV-1 Integrase Catalytical Core Domain
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, ARSENIC, HIV-1 Integrase, ...
著者Feng, L, Kvaratskhelia, M.
登録日2012-02-08
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
J.Biol.Chem., 287, 2012
3B4R
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BU of 3b4r by Molmil
Site-2 Protease from Methanocaldococcus jannaschii
分子名称: Putative zinc metalloprotease MJ0392, ZINC ION
著者Jeffrey, P.D, Feng, L, Yan, H, Wu, Z, Yan, N, Wang, Z, Shi, Y.
登録日2007-10-24
公開日2008-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of a site-2 protease family intramembrane metalloprotease.
Science, 318, 2007
3IA3
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BU of 3ia3 by Molmil
A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin
分子名称: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE
著者Feng, L, Jeffrey, P.D, Shi, Y.
登録日2009-07-13
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin.
J.Biol.Chem., 284, 2009
6NPK
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BU of 6npk by Molmil
Structure of the TM domain
分子名称: Solute carrier family 12 (sodium/potassium/chloride transporter), member 2
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPJ
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Structure of the NKCC1 CTD
分子名称: Sodium-potassium-chloride cotransporter 1
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPL
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Cryo-EM structure of NKCC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPH
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Structure of NKCC1 TM domain
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2020-01-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
4ID1
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BU of 4id1 by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Gag-Pol polyprotein, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2012-12-11
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6WDO
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BU of 6wdo by Molmil
Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+
分子名称: CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者Feng, L, Zhang, J, Fan, M.
登録日2020-04-01
公開日2020-05-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
6WDN
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BU of 6wdn by Molmil
Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+
分子名称: Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ...
著者Feng, L, Zhang, J, Fan, M.
登録日2020-04-01
公開日2020-05-27
最終更新日2020-06-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
5CTH
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BU of 5cth by Molmil
The 3.7 A resolution structure of a eukaryotic SWEET transporter
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Bidirectional sugar transporter SWEET2b, ...
著者Feng, L, Tao, Y, Perry, K.
登録日2015-07-24
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Structure of a eukaryotic SWEET transporter in a homotrimeric complex.
Nature, 527, 2015
4O5B
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BU of 4o5b by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4O55
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BU of 4o55 by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4O0J
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BU of 4o0j by Molmil
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[4-(4-chlorophenyl)-6-(3,4-dimethylphenyl)-2,5-dimethylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-13
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
8JJQ
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BU of 8jjq by Molmil
Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
分子名称: TIGR04348 family glycosyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Feng, L, Wei, H.
登録日2023-05-31
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
To Be Published
3BOE
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BU of 3boe by Molmil
Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2)
分子名称: ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase
著者Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
登録日2007-12-17
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3BOJ
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Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1)
分子名称: ACETATE ION, Cadmium-specific carbonic anhydrase
著者Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
登録日2007-12-17
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
3BOH
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Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1)
分子名称: ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase
著者Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M.
登録日2007-12-17
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
6R48
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Crystal structure of LPOR (Synechocystis) complexed with NADPH at 1.87A resolution.
分子名称: CHLORIDE ION, Light-dependent protochlorophyllide reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhou, A, Feng, L.
登録日2019-03-22
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
Nature, 574, 2019
6R46
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Crystal structure of LPOR (Thermosynechococcus elongatus) complexed with NADP+ at 2.5A resolution
分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase, ...
著者Zhou, A, Feng, L.
登録日2019-03-22
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
Nature, 574, 2019
6L62
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Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope
分子名称: Capsid protein, Heavy chain of Fab fragment, Light chain of Fab fragment
著者Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C.
登録日2019-10-25
公開日2020-02-12
最終更新日2020-04-29
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020

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