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8OER
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BU of 8oer by Molmil
MUC5B amino acids 26-1435
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B
著者Khmelnitsky, L, Fass, D.
登録日2023-03-12
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly
To Be Published
8OV0
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BU of 8ov0 by Molmil
MUC5AC CysD7 amino acids 3518-3626
分子名称: CALCIUM ION, CHLORIDE ION, Mucin-5AC
著者Khmelnitsky, L, Milo, A, Dym, O, Fass, D.
登録日2023-04-25
公開日2023-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Diversity of CysD domains in gel-forming mucins.
Febs J., 290, 2023
6GC2
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BU of 6gc2 by Molmil
AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface
分子名称: Heavy chain, Light Chain
著者Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J.
登録日2018-04-17
公開日2019-05-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
7POV
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BU of 7pov by Molmil
MUC2 Tubules of D1D2D3 domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Javitt, G, Fass, D.
登録日2021-09-10
公開日2022-02-16
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PP6
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BU of 7pp6 by Molmil
MUC2 Tubules of D1D2D3 domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Javitt, G, Fass, D.
登録日2021-09-13
公開日2022-02-16
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
3ED3
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BU of 3ed3 by Molmil
Crystal Structure of the Yeast Dithiol/Disulfide Oxidoreductase Mpd1p
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Protein disulfide-isomerase MPD1
著者Vitu, E, Greenblatt, H.M, Fass, D.
登録日2008-09-02
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Yeast Mpd1p reveals the structural diversity of the protein disulfide isomerase family
J.Mol.Biol., 384, 2008
1RP4
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BU of 1rp4 by Molmil
Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell
分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Gross, E, Kastner, D.B, Kaiser, C.A, Fass, D.
登録日2003-12-03
公開日2004-06-08
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of ero1p, source of disulfide bonds for oxidative protein folding in the cell.
Cell(Cambridge,Mass.), 117, 2004
4P2L
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BU of 4p2l by Molmil
Quiescin Sulfhydryl Oxidase from Rattus norvegicus
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
著者Gat, Y, Fass, D.
登録日2014-03-04
公開日2014-06-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Enzyme structure captures four cysteines aligned for disulfide relay.
Protein Sci., 23, 2014
4YEQ
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BU of 4yeq by Molmil
L4b Domain of Human Laminin alpha-2
分子名称: Laminin subunit alpha-2
著者Toot, M, Gat, Y, Fass, D.
登録日2015-02-24
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Laminin L4 domain structure resembles adhesion modules in ephrin receptor and other transmembrane glycoproteins.
Febs J., 282, 2015
4YEP
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BU of 4yep by Molmil
L4b Domain of Human Laminin alpha-2
分子名称: 1,2-ETHANEDIOL, Laminin subunit alpha-2
著者Toot, M, Gat, Y, Fass, D.
登録日2015-02-24
公開日2015-05-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Laminin L4 domain structure resembles adhesion modules in ephrin receptor and other transmembrane glycoproteins.
Febs J., 282, 2015
3GWL
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BU of 3gwl by Molmil
Crystal structure of ASFV pB119L, a viral sulfhydryl oxidase
分子名称: FAD-linked sulfhydryl oxidase, FLAVIN-ADENINE DINUCLEOTIDE
著者Hakim, M, Fass, D.
登録日2009-04-01
公開日2009-07-07
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dimer interface migration in a viral sulfhydryl oxidase
J.Mol.Biol., 391, 2009
3GWN
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BU of 3gwn by Molmil
Crystal structure of the FAD binding domain from mimivirus sulfhydryl oxidase R596
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Probable FAD-linked sulfhydryl oxidase R596, ...
著者Hakim, M, Fass, D.
登録日2009-04-01
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Dimer interface migration in a viral sulfhydryl oxidase
J.Mol.Biol., 391, 2009
1RQ1
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BU of 1rq1 by Molmil
Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell
分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Gross, E, Kastner, D.B, Kaiser, C.A, Fass, D.
登録日2003-12-04
公開日2004-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of ero1p, source of disulfide bonds for oxidative protein folding in the cell.
Cell(Cambridge,Mass.), 117, 2004
7PMV
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BU of 7pmv by Molmil
VWF Tubules of D1D2D'D3 domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Javitt, G, Fass, D.
登録日2021-09-02
公開日2022-02-23
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PNF
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BU of 7pnf by Molmil
VWF Tubules of D1D2D'D3 domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Javitt, G, Fass, D.
登録日2021-09-06
公開日2022-02-23
最終更新日2022-05-25
実験手法ELECTRON MICROSCOPY (4.35 Å)
主引用文献Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
5D8I
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BU of 5d8i by Molmil
Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma
分子名称: Sulfhydryl oxidase 1
著者Grossman, I, Fass, D.
登録日2015-08-17
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D93
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BU of 5d93 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
分子名称: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1
著者Grossman, I, Fass, D.
登録日2015-08-18
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
6TM2
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BU of 6tm2 by Molmil
Human MUC2 AAs 21-1397
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D.
登録日2019-12-03
公開日2020-10-21
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
6TM6
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BU of 6tm6 by Molmil
MUC2 CysD1 domain
分子名称: CALCIUM ION, Mucin-2
著者Khmelnitsky, L, Fass, D.
登録日2019-12-03
公開日2020-02-19
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
7O3I
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BU of 7o3i by Molmil
Cystal structure of Zymogen Granule Protein 16 (ZG16)
分子名称: CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16
著者Javitt, G, Fass, D.
登録日2021-04-01
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conformational switches and redox properties of the colon cancer-associated human lectin ZG16.
Febs J., 288, 2021
7O4P
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BU of 7o4p by Molmil
Cystal structure of Zymogen Granule Protein 16 (ZG16)
分子名称: CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16
著者Javitt, G, Fass, D.
登録日2021-04-07
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Conformational switches and redox properties of the colon cancer-associated human lectin ZG16.
Febs J., 288, 2021
7O88
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BU of 7o88 by Molmil
Cystal structure of Zymogen Granule Protein 16 (ZG16)
分子名称: GLYCEROL, Zymogen granule membrane protein 16
著者Javitt, G, Kinzel, A, Fass, D.
登録日2021-04-14
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Conformational switches and redox properties of the colon cancer-associated human lectin ZG16.
Febs J., 288, 2021
1LCS
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BU of 1lcs by Molmil
RECEPTOR-BINDING DOMAIN FROM SUBGROUP B FELINE LEUKEMIA VIRUS
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnett, A.L, Wensel, D.L, Li, W, Fass, D, Cunningham, J.M.
登録日2002-04-06
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Mechanism of a Coreceptor for Infection by a pathogenic feline retrovirus
J.Virol., 77, 2003
1JRA
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BU of 1jra by Molmil
Crystal Structure of Erv2p
分子名称: ERV2 PROTEIN, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE
著者Gross, E, Sevier, C.S, Vala, A, Kaiser, C.A, Fass, D.
登録日2001-08-13
公開日2001-12-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.
Nat.Struct.Biol., 9, 2002
1JR8
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BU of 1jr8 by Molmil
Crystal Structure of Erv2p
分子名称: Erv2 PROTEIN, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者Gross, E, Sevier, C.S, Vala, A, Kaiser, C.A, Fass, D.
登録日2001-08-13
公開日2001-12-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.
Nat.Struct.Biol., 9, 2002

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