8B9O
 
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8B9U
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6ZK7
 | | Crystal Structure of human PYROXD1/FAD complex | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | | 著者 | Meinhart, A, Asanovic, I, Martinez, J, Clausen, T. | | 登録日 | 2020-06-30 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
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3NWU
 | | Substrate induced remodeling of the active site regulates HtrA1 activity | | 分子名称: | SULFATE ION, Serine protease HTRA1 | | 著者 | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | | 登録日 | 2010-07-11 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
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3NUM
 | | Substrate induced remodeling of the active site regulates HtrA1 activity | | 分子名称: | Serine protease HTRA1 | | 著者 | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | | 登録日 | 2010-07-07 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
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3NZI
 | | Substrate induced remodeling of the active site regulates HtrA1 activity | | 分子名称: | Citrate synthase, Serine protease HTRA1 | | 著者 | Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M. | | 登録日 | 2010-07-16 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
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1POI
 | | CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55 ANGSTOMS RESOLUTION | | 分子名称: | COPPER (II) ION, GLUTACONATE COENZYME A-TRANSFERASE | | 著者 | Jacob, U, Mack, M, Clausen, T, Huber, R, Buckel, W, Messerschmidt, A. | | 登録日 | 1997-01-24 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases.
Structure, 5, 1997
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1QGN
 | | CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM | | 分子名称: | PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE | | 著者 | Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T. | | 登録日 | 1999-05-02 | | 公開日 | 1999-08-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
J.Mol.Biol., 290, 1999
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1SOT
 | | Crystal Structure of the DegS stress sensor | | 分子名称: | Protease degS | | 著者 | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | | 登録日 | 2004-03-15 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
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1SOZ
 | | Crystal Structure of DegS protease in complex with an activating peptide | | 分子名称: | Protease degS, activating peptide | | 著者 | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | | 登録日 | 2004-03-16 | | 公開日 | 2004-06-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
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7NH3
 | | Nematocida Huwe1 in open conformation. | | 分子名称: | E3 ubiquitin-protein ligase HUWE1 | | 著者 | Petrova, O, Grishkovskaya, I, Grabarczyk, D.B, Kessler, D, Haselbach, D, Clausen, T. | | 登録日 | 2021-02-09 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (6.37 Å) | | 主引用文献 | Crystal structure of HUWE1: One ring to ubiquitinate them all
To Be Published
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7OIM
 | | Mouse RNF213, with mixed nucleotides bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, E3 ubiquitin-protein ligase RNF213, ... | | 著者 | Grabarczyk, D, Ahel, J, Clausen, T. | | 登録日 | 2021-05-11 | | 公開日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP
To Be Published
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7OIK
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3MH6
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | 分子名称: | DIISOPROPYL PHOSPHONATE, Protease do | | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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3MH4
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3MH5
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | 分子名称: | DIISOPROPYL PHOSPHONATE, Protease do | | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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3MH7
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | 分子名称: | 5-mer peptide, Protease do | | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-30 | | 最終更新日 | 2014-03-05 | | 実験手法 | X-RAY DIFFRACTION (2.961 Å) | | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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4A8D
 | | DegP dodecamer with bound OMP | | 分子名称: | OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP | | 著者 | Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | | 登録日 | 2011-11-20 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (28 Å) | | 主引用文献 | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
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6QDJ
 | | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | | 分子名称: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Meinhart, A, Clausen, T, Arnese, R. | | 登録日 | 2019-01-02 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.884 Å) | | 主引用文献 | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
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6QDL
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6QDM
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6QDK
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1IXO
 | | Enzyme-analogue substrate complex of Pyridoxine 5'-Phosphate Synthase | | 分子名称: | Pyridoxine 5'-Phosphate synthase, SN-GLYCEROL-3-PHOSPHATE | | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | | 登録日 | 2002-06-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
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1IXQ
 | | Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase | | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-phosphate Synthase | | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | | 登録日 | 2002-06-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
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1IXP
 | | Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase | | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-Phosphate synthase | | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | | 登録日 | 2002-06-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
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