4JS8
| Crystal structure of TTK kinase domain with an inhibitor: 401348 | 分子名称: | 4-(cyclohexylmethoxy)-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-2H-indazole, DI(HYDROXYETHYL)ETHER, Dual specificity protein kinase TTK, ... | 著者 | Qiu, W, Plotnikov, A.N, Plotnikova, O, Feher, M, Awrey, D.E, Chirgadze, N.Y. | 登録日 | 2013-03-22 | 公開日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of TTK kinase domain with an inhibitor: 401348 To be Published
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4JXF
| Crystal Structure of PLK4 Kinase with an inhibitor: 400631 ((1R,2S)-2-{3-[(E)-2-{4-[(DIMETHYLAMINO)METHYL]PHENYL}ETHENYL]-2H-INDAZOL-6-YL}-5'-METHOXYSPIRO[CYCLOPROPANE-1,3'-INDOL]-2'(1'H)-ONE) | 分子名称: | (1R,2S)-2-{3-[(E)-2-{4-[(dimethylamino)methyl]phenyl}ethenyl]-2H-indazol-6-yl}-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'H)-one, 1,2-ETHANEDIOL, Serine/threonine-protein kinase PLK4 | 著者 | Qiu, W, Plotnikova, O, Feher, M, Awrey, D.E, Chirgadze, N.Y. | 登録日 | 2013-03-28 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of PLK4 Kinase with an inhibitor: 400631 To be Published
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1PCG
| Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions | 分子名称: | ESTRADIOL, estrogen receptor, peptide inhibitor | 著者 | Leduc, A.M, Trent, J.O, Wittliff, J.L, Bramlett, K.S, Briggs, S.L, Chirgadze, N.Y, Wang, Y, Burris, T.P, Spatola, A.F. | 登録日 | 2003-05-16 | 公開日 | 2003-10-28 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions Proc.Natl.Acad.Sci.USA, 100, 2003
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3NEA
| Crystal Structure of Peptidyl-tRNA hydrolase from Francisella tularensis | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-tRNA hydrolase | 著者 | Lam, R, McGrath, T.E, Romanov, V, Gothe, S.A, Peddi, S.R, Razumova, E, Lipman, R.S, Branstrom, A.A, Chirgadze, N.Y. | 登録日 | 2010-06-08 | 公開日 | 2011-06-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of Francisella tularensis peptidyl-tRNA hydrolase. Acta Crystallogr.,Sect.F, 67, 2011
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3NA8
| Crystal Structure of a putative dihydrodipicolinate synthetase from Pseudomonas aeruginosa | 分子名称: | D-MALATE, MAGNESIUM ION, putative dihydrodipicolinate synthetase | 著者 | Qiu, W, Lam, R, Romanov, V, Jones, K, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2010-06-01 | 公開日 | 2011-06-01 | 最終更新日 | 2012-02-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of a putative dihydrodipicolinate synthetase from Pseudomonas aeruginosa To be Published
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3NTV
| Crystal structure of a putative caffeoyl-CoA O-methyltransferase from Staphylococcus aureus | 分子名称: | MW1564 protein, SULFATE ION | 著者 | Qiu, W, Lam, R, Romanov, V, Jones, K, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2010-07-05 | 公開日 | 2011-07-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of a putative caffeoyl-CoA O-methyltransferase from Staphylococcus aureus TO BE PUBLISHED
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3NUR
| Crystal structure of a putative amidohydrolase from Staphylococcus aureus | 分子名称: | Amidohydrolase, CALCIUM ION | 著者 | Qiu, W, Lam, R, Romanov, V, Lam, K, Soloveychik, M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2010-07-07 | 公開日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of a putative amidohydrolase from Staphylococcus aureus To be Published
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3CXN
| Structure of the Urease Accessory Protein UreF from Helicobacter pylori | 分子名称: | GLYCEROL, Urease accessory protein ureF | 著者 | Lam, R, Johns, K, Romanov, V, Dong, A, Wu-Brown, J, Guthrie, J, Dharamsi, A, Thambipillai, D, Mansoury, K, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2008-04-24 | 公開日 | 2009-05-12 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori. Proteins, 78, 2010
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3D7R
| Crystal structure of a putative esterase from Staphylococcus aureus | 分子名称: | BROMIDE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Lam, R, Battaile, K.P, Chan, T, Romanov, V, Lam, K, Soloveychik, M, Wu-Brown, J, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2008-05-21 | 公開日 | 2009-06-09 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of a putative esterase from Staphylococcus aureus To be Published
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3E2I
| Crystal structure of Thymidine Kinase from S. aureus | 分子名称: | GLYCEROL, Thymidine kinase, ZINC ION | 著者 | Lam, R, Johns, K, Battaile, K.P, Romanov, V, Lam, K, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2008-08-05 | 公開日 | 2009-08-11 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of Thymidine Kinase from S. aureus To be Published
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3K29
| Structure of a putative YscO homolog CT670 from Chlamydia trachomatis | 分子名称: | Putative uncharacterized protein | 著者 | Lam, R, Singer, A, Skarina, T, Onopriyenko, O, Bochkarev, A, Brunzelle, J.S, Edwards, A.M, Anderson, W.F, Chirgadze, N.Y, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-09-29 | 公開日 | 2009-10-13 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and protein-protein interaction studies on Chlamydia trachomatis protein CT670 (YscO Homolog). J.Bacteriol., 192, 2010
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3I0U
| Structure of the type III effector/phosphothreonine lyase OspF from Shigella flexneri | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphothreonine lyase ospF | 著者 | Singer, A.U, Skarina, T, Nocek, B, Gordon, R, Lam, R, Kagan, O, Edwards, A.M, Joachimiak, A, Chirgadze, N.Y, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-06-25 | 公開日 | 2009-09-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the type III effector/phosphothreonine lyase OspF from Shigella flexneri TO BE PUBLISHED
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3K2A
| Crystal structure of the homeobox domain of human homeobox protein Meis2 | 分子名称: | ACETATE ION, CHLORIDE ION, Homeobox protein Meis2 | 著者 | Lam, R, Soloveychik, M, Battaile, K.P, Romanov, V, Lam, K, Beletskaya, I, Gordon, E, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-09-29 | 公開日 | 2010-10-13 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of the homeobox domain of human homeobox protein Meis2 To be Published
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3KBY
| Crystal structure of hypothetical protein from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, Putative uncharacterized protein | 著者 | Lam, R, Thompson, C.M, Battaile, K.P, Romanov, V, Kisselman, G, Gordon, E, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-10-20 | 公開日 | 2010-10-20 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of hypothetical protein from Staphylococcus aureus To be Published
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3KOR
| Crystal structure of a putative Trp repressor from Staphylococcus aureus | 分子名称: | Possible Trp repressor | 著者 | Lam, R, Vodsedalek, J, Lam, K, Romanov, V, Battaile, K.P, Beletskaya, I, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-11-13 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a putative Trp repressor from Staphylococcus aureus To be Published
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3L5A
| Crystal structure of a probable NADH-dependent flavin oxidoreductase from Staphylococcus aureus | 分子名称: | NADH/flavin oxidoreductase/NADH oxidase, TRIETHYLENE GLYCOL | 著者 | Lam, R, Gordon, R.D, Vodsedalek, J, Battaile, K.P, Grebemeskel, S, Lam, K, Romanov, V, Chan, T, Mihajlovic, V, Thompson, C.M, Guthrie, J, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-12-21 | 公開日 | 2010-12-22 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of a probable NADH-dependent flavin oxidoreductase from Staphylococcus aureus To be Published
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3KWL
| Crystal structure of a hypothetical protein from Helicobacter pylori | 分子名称: | uncharacterized protein | 著者 | Lam, R, Thompson, C.M, Vodsedalek, J, Lam, K, Romanov, V, Battaile, K.P, Beletskaya, I, Gordon, E, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-12-01 | 公開日 | 2010-12-01 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of a hypothetical protein from Helicobacter pylori To be Published
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3L20
| Crystal structure of a hypothetical protein from Staphylococcus aureus | 分子名称: | Putative uncharacterized protein | 著者 | Lam, R, Chan, T, Battaile, K.P, Mihajlovic, V, Romanov, V, Soloveychik, M, Kisselman, G, McGrath, T.E, Lam, K, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2009-12-14 | 公開日 | 2010-10-27 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | 主引用文献 | Crystal structure of a hypothetical protein from Staphylococcus aureus To be Published
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4TJW
| Crystal Structure of human Tankyrase 2 in complex with PJ-34. | 分子名称: | N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Tankyrase-2, ZINC ION | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-25 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TKG
| Crystal Structure of human Tankyrase 2 in complex with AZD2281. | 分子名称: | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, GLYCEROL, Tankyrase-2, ... | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-26 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TK5
| Crystal Structure of human Tankyrase 2 in complex with EB47. | 分子名称: | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Tankyrase-2, ZINC ION | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-25 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TJY
| Crystal Structure of human Tankyrase 2 in complex with ABT-888. | 分子名称: | 2-[(2S)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-7-carboxamide, Tankyrase-2, ZINC ION | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-25 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TKI
| Crystal Structure of human Tankyrase 2 in complex with BSI-201. | 分子名称: | 4-iodo-3-nitrobenzamide, ISOPROPYL ALCOHOL, Tankyrase-2, ... | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TJU
| Crystal Structure of human Tankyrase 2 in complex with 3,4-CPQ-5-C. | 分子名称: | 3-(4-CHLOROPHENYL)QUINOXALINE-5-CARBOXAMIDE, Tankyrase-2, ZINC ION | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-25 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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4TKF
| Crystal Structure of human Tankyrase 2 in complex with IWR-1. | 分子名称: | 3-aminobenzamide, 4-[(3aR,4R,7S,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-2, ... | 著者 | Qiu, W, Lam, R, Romanov, V, Gordon, R, Gebremeskel, S, Vodsedalek, J, Thompson, C, Beletskaya, I, Battaile, K.P, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-05-26 | 公開日 | 2014-11-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2. Acta Crystallogr.,Sect.D, 70, 2014
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