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7PWY
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BU of 7pwy by Molmil
Structure of human dimeric ACMSD in complex with the inhibitor TES-1025
分子名称: 2-[3-[(5-cyano-6-oxidanylidene-4-thiophen-2-yl-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]ethanoic acid, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, POTASSIUM ION, ...
著者Cianci, M, Giacche, N, Carotti, A, Liscio, P, Amici, A, Cialabrini, L, De Franco, F, Pellicciari, R, Raffaelli, N.
登録日2021-10-07
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Human Dimeric alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase Inhibition With TES-1025.
Front Mol Biosci, 9, 2022
8QQZ
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BU of 8qqz by Molmil
Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 8.0
分子名称: Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE
著者Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A.
登録日2023-10-06
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献A subgroup of light-driven sodium pumps with an additional Schiff base counterion.
Nat Commun, 15, 2024
8G9W
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BU of 8g9w by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Changela, A, Gorman, J, Kwong, P.D.
登録日2023-02-22
公開日2023-04-19
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8QR0
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BU of 8qr0 by Molmil
Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 4.3
分子名称: Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE
著者Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A.
登録日2023-10-06
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A subgroup of light-driven sodium pumps with an additional Schiff base counterion.
Nat Commun, 15, 2024
8G9Y
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BU of 8g9y by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Changela, A, Gorman, J, Kwong, P.D.
登録日2023-02-22
公開日2023-04-19
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4.28 Å)
主引用文献Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G9X
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BU of 8g9x by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者Changela, A, Gorman, J, Kwong, P.D.
登録日2023-02-22
公開日2023-04-19
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
6XKS
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BU of 6xks by Molmil
Crystal structure of domain A from the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) of Salmonella typhimurium
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, Histidine ABC transporter substrate-binding protein HisJ
著者Romero-Romero, S, Berrocal, T, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A.
登録日2020-06-27
公開日2021-07-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Thermodynamic and kinetic analysis of the LAO binding protein and its isolated domains reveal non-additivity in stability, folding and function.
Febs J., 2023
6NPN
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BU of 6npn by Molmil
Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine-3-hydroxyindazole inhibitor
分子名称: (7R)-7-methyl-2-[(3-oxo-2,3-dihydro-1H-indazol-6-yl)amino]-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5H)-one, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
著者Counago, R.M, dos Reis, C.V, Takarada, J.E, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC)
登録日2019-01-18
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropynyl-dihydropteridine-3-hydroxyindazole inhibitor
To Be Published
4UOW
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BU of 4uow by Molmil
Crystal structure of the titin M10-Obscurin Ig domain 1 complex
分子名称: CHLORIDE ION, Obscurin, SODIUM ION, ...
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2014-06-10
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.
J.Mol.Biol., 427, 2015
7PGX
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BU of 7pgx by Molmil
Structure of dark-adapted AsLOV2 wild type
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.001 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
7PGZ
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BU of 7pgz by Molmil
Structure of dark-adapted AsLOV2 Q513L
分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
7PH0
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BU of 7ph0 by Molmil
Structure of light-adapted AsLOV2 Q513L
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.979 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
6B18
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BU of 6b18 by Molmil
Crystal structure of PPK3 Class III in complex with inhibitor
分子名称: GLYCEROL, PHOSPHATE ION, PPK3 Class III, ...
著者Nocek, B, Ruszkowski, M, Berlicki, L, Joachimiak, A, Yakunin, A.
登録日2017-09-17
公開日2019-01-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into Substrate Selectivity and Activity of Bacterial Polyphosphate Kinases
Acs Catalysis, 8, 2018
7PGY
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BU of 7pgy by Molmil
Structure of light-adapted AsLOV2 wild type
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Gelfert, R, Weyand, M, Moeglich, A.
登録日2021-08-16
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
Nat Commun, 13, 2022
8FVR
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BU of 8fvr by Molmil
CryoEM structure of E.coli transcription elongation complex
分子名称: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Duan, W, Serganov, A.
登録日2023-01-19
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Control of transcription elongation and DNA repair by alarmone ppGpp.
Nat.Struct.Mol.Biol., 30, 2023
7JMH
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BU of 7jmh by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 35 - State 4 (S4)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
8FVW
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BU of 8fvw by Molmil
CryoEM structure of E.coli transcription elongation complex bound to ppGpp
分子名称: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Duan, W, Serganov, A.
登録日2023-01-19
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Control of transcription elongation and DNA repair by alarmone ppGpp.
Nat.Struct.Mol.Biol., 30, 2023
4UOR
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BU of 4uor by Molmil
Structure of lipoteichoic acid synthase LtaS from Listeria monocytogenes in complex with glycerol phosphate
分子名称: (2R)-2,3-dihydroxypropyl phosphate, LIPOTEICHOIC ACID SYNTHASE, MAGNESIUM ION
著者Campeotto, I, Freemont, P, Grundling, A.
登録日2014-06-09
公開日2014-08-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system.
J. Biol. Chem., 289, 2014
6R85
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BU of 6r85 by Molmil
Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-glutamate
分子名称: 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutamate receptor 3.3,Glutamate receptor 3.3, ...
著者Alfieri, A, Pederzoli, R, Costa, A.
登録日2019-03-31
公開日2020-01-01
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
5JEF
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BU of 5jef by Molmil
Fragment of nitrate/nitrite sensor histidine kinase NarQ (WT) in asymmetric holo state
分子名称: EICOSANE, NITRATE ION, Nitrate/nitrite sensor protein NarQ
著者Gushchin, I, Melnikov, I, Polovinkin, V, Ishchenko, A, Popov, A, Gordeliy, V.
登録日2016-04-18
公開日2017-05-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Mechanism of transmembrane signaling by sensor histidine kinases.
Science, 356, 2017
4U2T
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BU of 4u2t by Molmil
Cholesterol oxidase in the oxidised state complexed with isopropanol
分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Golden, E.A, Vrielink, A.
登録日2014-07-18
公開日2014-12-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.223 Å)
主引用文献High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
6XXO
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BU of 6xxo by Molmil
Crystal structure of NB8, a nanobody targeting prostate specific membrane antigen
分子名称: NB_8
著者Shahar, A, Rosenfeld, L, Papo, N.
登録日2020-01-28
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.
J.Med.Chem., 63, 2020
6XXP
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BU of 6xxp by Molmil
Crystal structure of NB37, a nanobody targeting prostate specific membrane antigen
分子名称: NB_37
著者Shahar, A, Rosenfeld, L, Papo, N.
登録日2020-01-28
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.
J.Med.Chem., 63, 2020
6XZ4
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BU of 6xz4 by Molmil
Crystal structure of TLNRD1
分子名称: Talin rod domain-containing protein 1
著者Cowell, A, Singh, A.K, Brown, D.G, Goult, B.T.
登録日2020-02-01
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation.
J.Cell Biol., 220, 2021
6XOK
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BU of 6xok by Molmil
X-ray structure of the rhombohedral form of the lipase from Thermomyces lanuginosa at 1.3 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate, Lipase, ...
著者McPherson, A.
登録日2020-07-07
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The crystal Structures of Thermomyces (Humicola) lanuginosa lipase in complex with enzymatic reactants
Current Enzyme Inhibition, 16, 2020

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件を2024-08-07に公開中

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