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6XXO

Crystal structure of NB8, a nanobody targeting prostate specific membrane antigen

Summary for 6XXO
Entry DOI10.2210/pdb6xxo/pdb
DescriptorNB_8 (2 entities in total)
Functional Keywordsnanobody, prostate-specific membrane antigen, antibody drug conjugate, cancer imaging, anti-cancer drugs., antitumor protein
Biological sourceCamelus dromedarius (Arabian camel)
Total number of polymer chains1
Total formula weight15714.06
Authors
Shahar, A.,Rosenfeld, L.,Papo, N. (deposition date: 2020-01-28, release date: 2020-06-10, Last modification date: 2024-01-24)
Primary citationRosenfeld, L.,Sananes, A.,Zur, Y.,Cohen, S.,Dhara, K.,Gelkop, S.,Ben Zeev, E.,Shahar, A.,Lobel, L.,Akabayov, B.,Arbely, E.,Papo, N.
Nanobodies Targeting Prostate-Specific Membrane Antigen for the Imaging and Therapy of Prostate Cancer.
J.Med.Chem., 63:7601-7615, 2020
Cited by
PubMed: 32442375
DOI: 10.1021/acs.jmedchem.0c00418
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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