6L4S
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5HS5
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5XWP
| Crystal structure of LbuCas13a-crRNA-target RNA ternary complex | 分子名称: | RNA (30-MER), RNA (59-MER), Uncharacterized protein | 著者 | Liu, L, Li, X, Li, Z, Wang, Y. | 登録日 | 2017-06-30 | 公開日 | 2017-09-13 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.086 Å) | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a. Cell, 170, 2017
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2G63
| Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 24b | 分子名称: | Dipeptidyl peptidase 4, METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE | 著者 | Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X. | 登録日 | 2006-02-24 | 公開日 | 2006-07-04 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J.Med.Chem., 49, 2006
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5J08
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5J8J
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2G5T
| Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag | 分子名称: | 3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOIC ACID, Dipeptidyl peptidase 4 | 著者 | Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X. | 登録日 | 2006-02-23 | 公開日 | 2006-07-04 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J.Med.Chem., 49, 2006
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2GO4
| Crystal structure of Aquifex aeolicus LpxC complexed with TU-514 | 分子名称: | 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL, CHLORIDE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... | 著者 | Gennadios, H.A, Whittington, D.A, Li, X, Fierke, C.A, Christianson, D.W. | 登録日 | 2006-04-12 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase Biochemistry, 45, 2006
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7DEO
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | 著者 | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-04 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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7DET
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | 著者 | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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7DEU
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | 著者 | Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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3HVN
| Crystal structure of cytotoxin protein suilysin from Streptococcus suis | 分子名称: | 1,1,1,3,3,3-hexafluoropropan-2-ol, HEPTANE-1,2,3-TRIOL, Hemolysin | 著者 | Xu, L, Huang, B, Du, H, Zhang, C.X, Xu, J, Li, X, Rao, Z. | 登録日 | 2009-06-16 | 公開日 | 2010-03-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.852 Å) | 主引用文献 | Crystal structure of cytotoxin protein suilysin from Streptococcus suis. Protein Cell, 1, 2010
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2G5P
| Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ac | 分子名称: | 4-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-3-TERT-BUTYLBENZOIC ACID, Dipeptidyl peptidase 4 | 著者 | Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X. | 登録日 | 2006-02-23 | 公開日 | 2006-07-04 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J.Med.Chem., 49, 2006
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2K3C
| Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger | 分子名称: | TMIX peptide | 著者 | Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K. | 登録日 | 2008-05-01 | 公開日 | 2008-06-03 | 最終更新日 | 2020-02-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. J.Biol.Chem., 283, 2008
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2GO3
| Crystal structure of Aquifex aeolicus LpxC complexed with imidazole. | 分子名称: | CHLORIDE ION, GLYCEROL, IMIDAZOLE, ... | 著者 | Gennadios, H.A, Whittington, D.A, Li, X, Fierke, C.A, Christianson, D.W. | 登録日 | 2006-04-12 | 公開日 | 2006-07-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase Biochemistry, 45, 2006
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2GVE
| Time-of-Flight Neutron Diffraction Structure of D-Xylose Isomerase | 分子名称: | COBALT (II) ION, Xylose isomerase | 著者 | Katz, A.K, Li, X, Carrell, H.L, Hanson, B.L, Langan, P, Coates, L, Schoenborn, B.P, Glusker, J.P, Bunick, G.J. | 登録日 | 2006-05-02 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-30 | 実験手法 | NEUTRON DIFFRACTION (2.2 Å) | 主引用文献 | Locating active-site hydrogen atoms in D-xylose isomerase: Time-of-flight neutron diffraction. Proc.Natl.Acad.Sci.Usa, 103, 2006
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6KNM
| Apelin receptor in complex with single domain antibody | 分子名称: | Apelin receptor,Rubredoxin,Apelin receptor, Single domain antibody JN241, ZINC ION | 著者 | Ma, Y.B, Ding, Y, Song, X, Ma, X, Li, X, Zhang, N, Song, Y, Sun, Y, Shen, Y, Zhong, W, Hu, L.A, Ma, Y.L, Zhang, M.Y. | 登録日 | 2019-08-06 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Sci Adv, 6, 2020
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3KXL
| crystal structure of SsGBP mutation variant G235S | 分子名称: | GTP-binding protein (HflX), THIOCYANATE ION | 著者 | Huang, B, Li, X, Zhang, X.C, Rao, Z. | 登録日 | 2009-12-03 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family. J.Biochem., 2010
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2KBV
| Structural and functional analysis of TM XI of the NHE1 isoform of thE NA+/H+ exchanger | 分子名称: | Sodium/hydrogen exchanger 1 | 著者 | Lee, B.L, Li, X, Liu, Y, Sykes, B.D, Fliegel, L. | 登録日 | 2008-12-09 | 公開日 | 2009-01-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger J.Biol.Chem., 284, 2009
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8WZ2
| Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex | 分子名称: | G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor. Cell Discov, 10, 2024
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5D1I
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5EBG
| Crystal structure of bovine CD8aa homodimer | 分子名称: | T-cell surface glycoprotein CD8 alpha chain | 著者 | Liu, Y, Li, X, Zhang, N, Qi, J, Xia, C. | 登録日 | 2015-10-19 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
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8TWU
| Crystal structure of Cytochrome P450 AspB bound to N1-methylated cyclo-L-Trp-L-Pro | 分子名称: | (3S,5S,8aS)-3-[(1-methyl-1H-indol-3-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cytochrome P450 AspB, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gering, H.E, Li, X, Tang, H, Swartz, P.D, Chang, W.-C, Makris, T.M. | 登録日 | 2023-08-21 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. J.Am.Chem.Soc., 145, 2023
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7DCY
| Apo form of Mycoplasma genitalium RNase R | 分子名称: | MAGNESIUM ION, Ribonuclease R | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | 登録日 | 2020-10-27 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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7DIC
| Mycoplasma genitalium RNase R in complex with single-stranded RNA | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | 登録日 | 2020-11-18 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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