8JGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgu by Molmil](/molmil-images/mine/8jgu) | |
8JGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgq by Molmil](/molmil-images/mine/8jgq) | |
8JGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgo by Molmil](/molmil-images/mine/8jgo) | |
8JGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jgp by Molmil](/molmil-images/mine/8jgp) | |
5IL1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5il1 by Molmil](/molmil-images/mine/5il1) | Crystal structure of SAM-bound METTL3-METTL14 complex | 分子名称: | 1,2-ETHANEDIOL, METTL14, METTL3, ... | 著者 | Wang, X, Guan, Z, Zou, T, Yin, P. | 登録日 | 2016-03-04 | 公開日 | 2016-05-25 | 最終更新日 | 2016-06-29 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
|
|
5IL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5il0 by Molmil](/molmil-images/mine/5il0) | Crystal structural of the METTL3-METTL14 complex for N6-adenosine methylation | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, METTL14, ... | 著者 | Wang, X, Guan, Z, Zou, T, Yin, P. | 登録日 | 2016-03-04 | 公開日 | 2016-05-25 | 最終更新日 | 2016-06-29 | 実験手法 | X-RAY DIFFRACTION (1.882 Å) | 主引用文献 | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
|
|
5IL2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5il2 by Molmil](/molmil-images/mine/5il2) | Crystal structure of SAH-bound METTL3-METTL14 complex | 分子名称: | 1,2-ETHANEDIOL, METTL14, METTL3, ... | 著者 | Wang, X, Guan, Z, Zou, T, Yin, P. | 登録日 | 2016-03-04 | 公開日 | 2016-05-25 | 最終更新日 | 2016-06-29 | 実験手法 | X-RAY DIFFRACTION (1.606 Å) | 主引用文献 | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
|
|
5XN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xn3 by Molmil](/molmil-images/mine/5xn3) | |
8AX1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ax1 by Molmil](/molmil-images/mine/8ax1) | |
5WWD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wwd by Molmil](/molmil-images/mine/5wwd) | Crystal structure of AtNUDX1 | 分子名称: | AMMONIUM ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P. | 登録日 | 2016-12-31 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.386 Å) | 主引用文献 | Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis. Mol Plant, 11, 2018
|
|
5WY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wy6 by Molmil](/molmil-images/mine/5wy6) | Crystal structure of AtNUDX1 (E56A) | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Nudix hydrolase 1, ... | 著者 | Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P. | 登録日 | 2017-01-11 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.779 Å) | 主引用文献 | Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis. Mol Plant, 11, 2018
|
|
7V9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v9u by Molmil](/molmil-images/mine/7v9u) | Cryo-EM structure of E.coli retron-Ec86 (RT-msDNA-RNA) at 3.2 angstrom | 分子名称: | DNA (105-MER), RNA (5'-R(P*CP*GP*UP*AP*AP*GP*GP*G)-3'), RNA (81-MER), ... | 著者 | Wang, Y.J, Guan, Z.Y, Zou, T.T. | 登録日 | 2021-08-26 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism. Nat Microbiol, 7, 2022
|
|
6JJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jj3 by Molmil](/molmil-images/mine/6jj3) | BRD4 in complex with 138A | 分子名称: | 2-methoxy-N-[2-methyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]benzenesulfonamide, Bromodomain-containing protein 4 | 著者 | Xu, J, Chen, Y, Jiang, F, Zhu, J. | 登録日 | 2019-02-25 | 公開日 | 2020-01-22 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.718 Å) | 主引用文献 | Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis. J.Med.Chem., 62, 2019
|
|
7SMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7smg by Molmil](/molmil-images/mine/7smg) | Crystal structure of a (p)ppApp hydrolase from Bacteroides caccae | 分子名称: | (p)ppApp hydrolase, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Ahmad, S, Alexei, A.G, Tsang, K.K, Trilesky, S, Kim, Y, Whitney, J.C. | 登録日 | 2021-10-25 | 公開日 | 2022-11-09 | 最終更新日 | 2023-05-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
5CZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5czb by Molmil](/molmil-images/mine/5czb) | HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5 | 分子名称: | 1-[4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl]-3-{[(R)-(2,4-dimethylphenyl)(methoxy)phosphoryl]amino}-1H-pyrazole-4-carboxylic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pierra, C, Dousson, C, Augustin, M. | 登録日 | 2015-07-31 | 公開日 | 2016-06-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase. Bioorg.Med.Chem.Lett., 26, 2016
|
|
3EE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ee1 by Molmil](/molmil-images/mine/3ee1) | |
7WVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wvm by Molmil](/molmil-images/mine/7wvm) | The complex structure of PD-1 and cemiplimab | 分子名称: | Heavy Chain of Cemiplimab, Light Chain of Cemiplimab, Programmed cell death protein 1 | 著者 | Lu, D, Xu, Z.P, Liu, K.F, Tan, S.G, Gao, G.F, Chai, Y. | 登録日 | 2022-02-10 | 公開日 | 2022-04-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy. Front Immunol, 13, 2022
|
|
7D5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d5k by Molmil](/molmil-images/mine/7d5k) | CryoEM structure of cotton cellulose synthase isoform 7 | 分子名称: | Cellulose synthase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Guan, Z.Y, Xue, Y, Yin, P, Zhang, X.L. | 登録日 | 2020-09-26 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into homotrimeric assembly of cellulose synthase CesA7 from Gossypium hirsutum. Plant Biotechnol J, 19, 2021
|
|
7DEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7deg by Molmil](/molmil-images/mine/7deg) | Cryo-EM structure of a heme-copper terminal oxidase dimer provides insights into its catalytic mechanism | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-[(2~{E},6~{E},10~{Z},14~{Z},18~{Z},23~{R})-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18-pentaenyl]naphthalene-1,4-dione, ... | 著者 | Fei, S, Hartmut, M, Yun, Z, Guoliang, Z, Shuangbo, Z. | 登録日 | 2020-11-04 | 公開日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The Unusual Homodimer of a Heme-Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6A53
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a53 by Molmil](/molmil-images/mine/6a53) | Crystal structure of DddK | 分子名称: | MANGANESE (II) ION, Novel protein with potential Cupin domain | 著者 | Zhang, Y.Z, Li, C.Y. | 登録日 | 2018-06-21 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-Function Analysis Indicates that an Active-Site Water Molecule Participates in Dimethylsulfoniopropionate Cleavage by DddK. Appl. Environ. Microbiol., 85, 2019
|
|
7D3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d3y by Molmil](/molmil-images/mine/7d3y) | Crystal structure of the osPHR2-osSPX2 complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | 著者 | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | 登録日 | 2020-09-21 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
|
|
7D3T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d3t by Molmil](/molmil-images/mine/7d3t) | Crystal structure of OSPHR2 in complex with DNA | 分子名称: | DNA (5'-D(P*CP*TP*CP*GP*GP*AP*TP*AP*TP*CP*CP*TP*CP*AP*AP*G)-3'), DNA (5'-D(P*GP*CP*TP*TP*GP*AP*GP*GP*AP*TP*AP*TP*CP*CP*GP*A)-3'), Protein PHOSPHATE STARVATION RESPONSE 2 | 著者 | Guan, Z.Y, Zhang, Z.F, Liu, Z. | 登録日 | 2020-09-20 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
|
|
4ZOT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zot by Molmil](/molmil-images/mine/4zot) | Crystal structure of BbKI, a disulfide-free plasma kallikrein inhibitor at 1.4 A resolution | 分子名称: | Kunitz-type serine protease inhibitor BbKI | 著者 | Shabalin, I.G, Zhou, D, Wlodawer, A, Oliva, M.L.V. | 登録日 | 2015-05-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure of BbKI, a disulfide-free plasma kallikrein inhibitor. Acta Crystallogr.,Sect.F, 71, 2015
|
|
3CXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cxd by Molmil](/molmil-images/mine/3cxd) | Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | 著者 | Du, J, Yang, H, Zhong, C, Ding, J. | 登録日 | 2008-04-24 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis J.Mol.Biol., 382, 2008
|
|
1VJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vj3 by Molmil](/molmil-images/mine/1vj3) | STRUCTURAL STUDIES ON BIO-ACTIVE COMPOUNDS. CRYSTAL STRUCTURE AND MOLECULAR MODELING STUDIES ON THE PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COFACTOR COMPLEX WITH TAB, A HIGHLY SELECTIVE ANTIFOLATE. | 分子名称: | ACETIC ACID N-[2-CHLORO-5-[6-ETHYL-2,4-DIAMINO-PYRIMID-5-YL]-PHENYL]-[BENZYL-TRIAZEN-3-YL]ETHYL ESTER, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Rak, D, Luft, J.R, Queener, S.F, Laughton, C.A, Malcolm, F.G. | 登録日 | 2004-01-13 | 公開日 | 2004-01-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate. Biochemistry, 39, 2000
|
|