7CZX
 
 | | S protein of SARS-CoV-2 in complex bound with P5A-1B9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IG c168_light_IGKV4-1_IGKJ4,Uncharacterized protein, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZY
 | | S protein of SARS-CoV-2 in complex bound with P5A-2F11_2B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZZ
 | | S protein of SARS-CoV-2 in complex bound with P5A-2F11_3B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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7CZW
 | | S protein of SARS-CoV-2 in complex bound with P5A-2G7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IGL c2312_light_IGLV2-14_IGLJ2,IGL@ protein, ... | | 著者 | Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Cell Res., 31, 2021
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4ONN
 | | Crystal structure of human Mms2/Ubc13 - BAY 11-7082 | | 分子名称: | 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... | | 著者 | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | | 登録日 | 2014-01-28 | | 公開日 | 2015-05-06 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
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4ONL
 | | Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P | | 分子名称: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | | 著者 | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | | 登録日 | 2014-01-28 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
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4OUL
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7EPX
 | | S protein of SARS-CoV-2 in complex with GW01 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Shen, Y.P, Zhang, Y.Y, Yan, R.H, Li, Y.N, Zhou, Q. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses.
Cell Discov, 8, 2022
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2MDI
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7W9N
 | | THE STRUCTURE OF OBA33-OTA COMPLEX | | 分子名称: | (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid, OTA DNA APTAMER (33-MER) | | 著者 | Xu, G.H, Li, C.G. | | 登録日 | 2021-12-10 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insights into the Mechanism of High-Affinity Binding of Ochratoxin A by a DNA Aptamer.
J.Am.Chem.Soc., 144, 2022
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8ISS
 | | Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution | | 分子名称: | MAGNESIUM ION, RNA (88-MER), tRNA-splicing endonuclease subunit Sen15, ... | | 著者 | Sun, Y, Zhang, Y, Yuan, L, Han, Y. | | 登録日 | 2023-03-21 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex.
Nat Commun, 14, 2023
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8K46
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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8K45
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nb4 nanobody, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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8K47
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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8KAE
 | | 16d-bound human SPNS2 | | 分子名称: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, NbFab chain L, NbFab-H chain, ... | | 著者 | He, Y, Duan, Y. | | 登録日 | 2023-08-03 | | 公開日 | 2024-01-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
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8K3K
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7Y8B
 | | Crystal structure of CotA laccase complexed with syringic acid | | 分子名称: | 3,5-dimethoxy-4-oxidanyl-benzoic acid, COPPER (II) ION, Spore coat protein A, ... | | 著者 | Liu, Z.C, Xie, T, Wang, G.G. | | 登録日 | 2022-06-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insights into substrate promiscuity of CotA laccase catalyzing lignin-phenol derivatives.
Int.J.Biol.Macromol., 256, 2023
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7Y8C
 | | Crystal structure of CotA laccase complexed with syringaldehyde | | 分子名称: | 3,5-dimethoxy-4-oxidanyl-benzaldehyde, COPPER (II) ION, Spore coat protein A, ... | | 著者 | Liu, Z.C, Xie, T, Wang, G.G. | | 登録日 | 2022-06-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular insights into substrate promiscuity of CotA laccase catalyzing lignin-phenol derivatives.
Int.J.Biol.Macromol., 256, 2023
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7WOR
 | | The state 2 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOS
 | | The state 3 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOQ
 | | The state 1 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOP
 | | The local refined map of Omicron spike with bispecific antibody FD01 | | 分子名称: | 16L9, GW01, Spike protein S1 | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOU
 | | The state 4 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOW
 | | The state 6 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, GW01 Fv, Spike glycoprotein | | 著者 | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (6.11 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7WOV
 | | The state 5 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | | 著者 | Zhang, X, Zhan, W.Q, Sun, L, Chen, Z.G. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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