1EV8
| CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | 分子名称: | THYMIDYLATE SYNTHASE | 著者 | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | 登録日 | 2000-04-19 | 公開日 | 2000-05-03 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
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1EG7
| THE CRYSTAL STRUCTURE OF FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA | 分子名称: | FORMYLTETRAHYDROFOLATE SYNTHETASE, SULFATE ION | 著者 | Radfar, R, Shin, R, Sheldrick, G.M, Minor, W, Lovell, C.R, Odom, J.D, Dunlap, R.B, Lebioda, L. | 登録日 | 2000-02-14 | 公開日 | 2001-02-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of N(10)-formyltetrahydrofolate synthetase from Moorella thermoacetica. Biochemistry, 39, 2000
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1EVF
| CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | 分子名称: | SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | 登録日 | 2000-04-19 | 公開日 | 2000-05-03 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
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1EV5
| CRYSTAL STRUCTURE ANALYSIS OF ALA167 MUTANT OF ESCHERICHIA COLI | 分子名称: | SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | 登録日 | 2000-04-19 | 公開日 | 2000-05-03 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
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1EVG
| CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI WITH UNMODIFIED CATALYTIC CYSTEINE | 分子名称: | SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | 登録日 | 2000-04-19 | 公開日 | 2000-05-03 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
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7KYJ
| Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Acetyltransferase PA3944, ... | 著者 | Czub, M.P, Porebski, P.J, Cymborowski, M, Shabalin, I.G, Reidl, C.T, Becker, D.P, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-07 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc To Be Published
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7KPP
| Structure of the E102A mutant of a GNAT superfamily PA3944 acetyltransferase | 分子名称: | 1,2-ETHANEDIOL, Acetyltransferase PA3944, COENZYME A, ... | 著者 | Czub, M.P, Porebski, P.J, Majorek, K.A, Cymborowski, M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-11-12 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Gcn5-Related N- Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too. Front Mol Biosci, 8, 2021
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1FP7
| MONOVALENT CATION BINDING SITES IN N10-FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA | 分子名称: | FORMATE--TETRAHYDROFOLATE LIGASE, POTASSIUM ION, SULFATE ION | 著者 | Radfar, R, Leaphart, A, Brewer, J.M, Minor, W, Odom, J.D. | 登録日 | 2000-08-30 | 公開日 | 2001-08-30 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica. Biochemistry, 39, 2000
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1FPM
| MONOVALENT CATION BINDING SITES IN N10-FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA | 分子名称: | CESIUM ION, FORMATE--TETRAHYDROFOLATE LIGASE, SULFATE ION | 著者 | Radfar, R, Leaphart, A, Brewer, J.M, Minor, W, Odom, J.D. | 登録日 | 2000-08-31 | 公開日 | 2001-08-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica. Biochemistry, 39, 2000
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7JWN
| Crystal structure of Human Serum Albumin in complex with ketoprofen | 分子名称: | (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, (R)-Ketoprofen, 1,2-ETHANEDIOL, ... | 著者 | Czub, M.P, Shabalin, I.G, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-08-25 | 公開日 | 2020-09-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Organism-specific differences in the binding of ketoprofen to serum albumin. Iucrj, 9, 2022
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1FTN
| CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | 著者 | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | 登録日 | 1997-03-13 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of RhoA-GDP and its functional implications. Nat.Struct.Biol., 4, 1997
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7KPS
| Structure of a GNAT superfamily PA3944 acetyltransferase in complex with AcCoA | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYL COENZYME *A, ... | 著者 | Czub, M.P, Porebski, P.J, Cymborowski, M, Reidl, C.T, Becker, D.P, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-11-12 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Gcn5-Related N- Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too. Front Mol Biosci, 8, 2021
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7KYE
| Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetyltransferase PA3944, ... | 著者 | Czub, M.P, Porebski, P.J, Cymborowski, M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-07 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES To Be Published
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7LBQ
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7LBK
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7LBP
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1TE6
| Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ... | 著者 | Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L. | 登録日 | 2004-05-24 | 公開日 | 2004-09-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase J.Mol.Biol., 341, 2004
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1T9K
| X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima] | 分子名称: | CHLORIDE ION, Probable methylthioribose-1-phosphate isomerase, SULFATE ION | 著者 | Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-05-17 | 公開日 | 2004-06-08 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | X-ray crystal structure of aIF-2B translation initiation factor from Thermotoga maritima To be Published
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1TU1
| Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Osipiuk, J, Evdokimova, E, Savchenko, A, Edwards, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-06-24 | 公開日 | 2004-08-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | X-ray crystal structure of hypothetical protein PA94 from Pseudomonas aeruginosa To be Published
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1SFX
| X-ray crystal structure of putative HTH transcription regulator from Archaeoglobus fulgidus | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Conserved hypothetical protein AF2008 | 著者 | Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-02-20 | 公開日 | 2004-08-03 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | X-ray crystal structure of putative HTH transcription regulator from Archaeoglobus fulgidus To be Published
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1UXO
| The crystal structure of the ydeN gene product from B. subtilis | 分子名称: | Putative hydrolase YdeN | 著者 | Janda, I.K, Devedjiev, Y, Cooper, D.R, Chruszcz, M, Derewenda, U, Gabrys, A, Minor, W, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-02-27 | 公開日 | 2004-05-27 | 最終更新日 | 2022-05-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution. Acta Crystallogr. D Biol. Crystallogr., 60, 2004
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1HW4
| STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. | 登録日 | 2001-01-09 | 公開日 | 2001-01-24 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors. J.Biol.Chem., 276, 2001
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1IW2
| X-ray structure of Human Complement Protein C8gamma at pH=7.O | 分子名称: | Complement Protein C8gamma | 著者 | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | 登録日 | 2002-04-11 | 公開日 | 2002-06-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. Biochemistry, 41, 2002
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1HW3
| STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. | 登録日 | 2001-01-09 | 公開日 | 2001-01-24 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors. J.Biol.Chem., 276, 2001
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1HVY
| Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, BETA-MERCAPTOETHANOL, THYMIDYLATE SYNTHASE, ... | 著者 | Phan, J, Koli, S, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L. | 登録日 | 2001-01-08 | 公開日 | 2001-01-31 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug Biochemistry, 40, 2001
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