1EVG
CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI WITH UNMODIFIED CATALYTIC CYSTEINE
Summary for 1EVG
Entry DOI | 10.2210/pdb1evg/pdb |
Related | 1EV5 1EV8 1EVF |
Descriptor | THYMIDYLATE SYNTHASE, SULFATE ION (3 entities in total) |
Functional Keywords | thr167 e. coli thymidylate synthase with unmodified catalytic cysteine, transferase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm : P0A884 |
Total number of polymer chains | 1 |
Total formula weight | 31014.11 |
Authors | Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. (deposition date: 2000-04-19, release date: 2000-05-03, Last modification date: 2022-04-13) |
Primary citation | Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39:6969-6978, 2000 Cited by PubMed: 10841779DOI: 10.1021/bi000367g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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