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8H8E
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Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state)
分子名称: Proton-activated chloride channel, tRNA (75-MER)of Spodoptera frugiperda
著者Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D.
登録日2022-10-22
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state)
To Be Published
8H8D
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Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state)
分子名称: Proton-activated chloride channel
著者Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D.
登録日2022-10-22
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state)
To Be Published
8IG4
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Crystal structure of SARS-Cov-2 main protease in complex with GC376
分子名称: Non-structural protein 11, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zhou, X.L, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG7
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Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, P, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG5
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Crystal structure of SARS main protease in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG6
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Crystal structure of MERS main protease in complex with GC376
分子名称: N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, ORF1a
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG8
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Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG9
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Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zou, X.F, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IGA
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BU of 8iga by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Wang, J, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IM6
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Crystal structure of HCoV 229E main protease in complex with PF07304814
分子名称: 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate
著者Zhou, Y.R, Zeng, P, Zhang, J, Li, J.
登録日2023-03-06
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332.
Biochem.Biophys.Res.Commun., 657, 2023
1ES9
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BU of 1es9 by Molmil
X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH)
分子名称: PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT
著者McMullen, T.W.P, Li, J, Sheffield, P.J, Aoki, J, Martin, T.W, Arai, H, Inoue, K, Derewenda, Z.S.
登録日2000-04-07
公開日2000-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib).
Protein Eng., 13, 2000
5V7Z
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BU of 5v7z by Molmil
SSNMR Structure of the Human RIP1/RIP3 Necrosome
分子名称: PRO-LEU-VAL-ASN-ILE-TYR-ASN-CYS-SER-GLY-VAL-GLN-VAL-GLY-ASP, THR-ILE-TYR-ASN-SER-THR-GLY-ILE-GLN-ILE-GLY-ALA-TYR-ASN-TYR-MET-GLU-ILE
著者Mompean, M, Li, W, Li, J, Laage, S, Siemer, A.B, Wu, H, McDermott, A.E.
登録日2017-03-21
公開日2018-03-28
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.
Cell, 173, 2018
7KQ2
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1.98 A resolution crystal structure of Group A Streptococcus H111A HupZ-V5-His6
分子名称: GLYCEROL, HupZ, SULFATE ION
著者Traore, E, Li, J, Liu, A.
登録日2020-11-13
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Heme Binding to HupZ with a C-Terminal Tag from Group A Streptococcus.
Molecules, 26, 2021
2ZKJ
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BU of 2zkj by Molmil
Crystal structure of human PDK4-ADP complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Li, J, Chuang, D.T.
登録日2008-03-25
公開日2008-08-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity
J.Biol.Chem., 283, 2008
2ZJG
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BU of 2zjg by Molmil
Crystal structural of mouse kynurenine aminotransferase III
分子名称: GLYCEROL, Kynurenine-oxoglutarate transaminase 3
著者Han, Q, Cai, T, Tagle, D.A, Robinson, H, Li, J.
登録日2008-03-07
公開日2009-01-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional characterization of mouse kynurenine aminotransferase III
To be Published
4GHQ
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BU of 4ghq by Molmil
Crystal structure of EV71 3C proteinase
分子名称: 3C proteinase
著者Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T.
登録日2012-08-08
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
1MI1
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BU of 1mi1 by Molmil
Crystal Structure of the PH-BEACH Domain of Human Neurobeachin
分子名称: Neurobeachin
著者Jogl, G, Shen, Y, Gebauer, D, Li, J, Wiegmann, K, Kashkar, H, Kroenke, M, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2002-08-21
公開日2002-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
EMBO J., 21, 2002
2QLD
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BU of 2qld by Molmil
human Hsp40 Hdj1
分子名称: DnaJ homolog subfamily B member 1
著者Hu, J, Wu, Y, Li, J, Fu, Z, Sha, B.
登録日2007-07-12
公開日2008-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
5DQZ
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Crystal Structure of Cas-DNA-PAM complex
分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (36-MER), ...
著者Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y.
登録日2015-09-15
公開日2015-11-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
8HUW
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BU of 8huw by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with S217622
分子名称: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
著者Wang, J, Zhang, J, Li, J.
登録日2022-12-24
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
8HUX
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Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with S217622
分子名称: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
著者Li, W.W, Zhang, J, Li, J.
登録日2022-12-24
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
8H93
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Structure of dimeric mouse SCMC core complex
分子名称: NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ...
著者Chi, P, Ou, G, Han, Z, Li, J, Deng, D.
登録日2022-10-24
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural basis of the subcortical maternal complex and its implications in reproductive disorders.
Nat.Struct.Mol.Biol., 31, 2024
8H94
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Structure of mouse SCMC bound with KH domain of FILIA
分子名称: NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ...
著者Chi, P, Ou, G, Han, Z, Li, J, Deng, D.
登録日2022-10-24
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of the subcortical maternal complex and its implications in reproductive disorders.
Nat.Struct.Mol.Biol., 31, 2024
8H96
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Structure of mouse SCMC core complex
分子名称: NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ...
著者Chi, P, Ou, G, Li, J, Han, Z, Deng, D.
登録日2022-10-24
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Structural basis of the subcortical maternal complex and its implications in reproductive disorders.
Nat.Struct.Mol.Biol., 31, 2024
6J72
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Crystal structure of IniA from Mycobacterium smegmatis with GTP bound
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ...
著者Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
登録日2019-01-16
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019

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件を2024-07-10に公開中

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