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7KNE
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BU of 7kne by Molmil
Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNI
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BU of 7kni by Molmil
Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNB
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BU of 7knb by Molmil
Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-09
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMB
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BU of 7kmb by Molmil
ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Kwong, P.D, Shapiro, L.
登録日2020-11-02
公開日2020-12-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNH
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BU of 7knh by Molmil
Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMS
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BU of 7kms by Molmil
Cryo-EM structure of triple ACE2-bound SARS-CoV-2 trimer spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Kwong, P.D, Shapiro, L.
登録日2020-11-03
公開日2020-12-09
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMZ
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BU of 7kmz by Molmil
Cryo-EM structure of double ACE2-bound SARS-CoV-2 trimer Spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Kwong, P.D, Shapiro, L.
登録日2020-11-03
公開日2020-12-09
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7L0L
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BU of 7l0l by Molmil
Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ...
著者Gorman, J, Kwong, P.D.
登録日2020-12-11
公開日2021-11-03
最終更新日2022-03-09
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Nat Med, 28, 2022
7LY9
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BU of 7ly9 by Molmil
Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2909 Heavy Chain, ...
著者Gorman, J, Kwong, P.D.
登録日2021-03-06
公開日2021-08-18
最終更新日2021-11-24
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.
Nat Commun, 12, 2021
7LPN
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BU of 7lpn by Molmil
Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Gorman, J, Kwong, P.D.
登録日2021-02-12
公開日2022-02-23
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7LKG
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BU of 7lkg by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151
分子名称: Circumsporozoite protein, m43.151 Fab Heavy Chain, m43.151 Fab Light chain
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7LKB
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BU of 7lkb by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127
分子名称: Circumsporozoite protein, SULFATE ION, m42.127 Fab heavy Chain, ...
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7LZE
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BU of 7lze by Molmil
Cryo-EM Structure of disulfide stabilized HMPV F v4-B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Gorman, J, Kwong, P.D.
登録日2021-03-09
公開日2021-08-25
最終更新日2021-10-06
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MFB
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BU of 7mfb by Molmil
Crystal structure of antibody 10E8v4 Fab - light chain H31F variant
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MFA
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BU of 7mfa by Molmil
Crystal structure of antibody 10E8v4-P100fA+P100gA Fab
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF8
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BU of 7mf8 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF7
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BU of 7mf7 by Molmil
Crystal structure of antibody 10E8v4-P100gA Fab
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF9
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BU of 7mf9 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group C2
分子名称: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
著者Kwon, Y.D, Kwong, P.D.
登録日2021-04-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7KC1
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BU of 7kc1 by Molmil
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Gorman, J, Kwong, P.D.
登録日2020-10-04
公開日2021-05-12
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.
Front Immunol, 12, 2021
7JZI
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BU of 7jzi by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
分子名称: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2021-09-22
実験手法X-RAY DIFFRACTION (2.707 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ4
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BU of 7jz4 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZK
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BU of 7jzk by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain
分子名称: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ1
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BU of 7jz1 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
分子名称: MGC34 heavy chain, MGC34 light chain
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7MM0
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BU of 7mm0 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ...
著者Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日2021-04-29
公開日2021-07-28
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
7MLZ
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BU of 7mlz by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
分子名称: B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ...
著者Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日2021-04-29
公開日2021-07-28
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021

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