4OCC
 
 | | co-crystal structure of MDM2(17-111) in complex with compound 48 | | 分子名称: | E3 ubiquitin-protein ligase Mdm2, [(2R,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid | | 著者 | Huang, X. | | 登録日 | 2014-01-08 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
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4ODF
 | | Co-Crystal Structure of MDM2 with Inhibitor Compound 47 | | 分子名称: | 6-{[(2S,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. | | 登録日 | 2014-01-10 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2006 Å) | | 主引用文献 | Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
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7N8L
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7N8M
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7N8E
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4ODE
 | | Co-Crystal Structure of MDM2 with Inhibitor Compound 4 | | 分子名称: | (2-{[(3R,5R,6S)-1-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl}-1,3-thiazol-5-yl)acetic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | 著者 | Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. | | 登録日 | 2014-01-10 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres.
J.Med.Chem., 57, 2014
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1TB3
 | | Crystal Structure Analysis of Recombinant Rat Kidney Long-chain Hydroxy Acid Oxidase | | 分子名称: | ACETIC ACID, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 3 | | 著者 | Cunane, L.M, Barton, J.D, Chen, Z.W, Le, K.H.D, Amar, D, Lederer, F, Mathews, F.S. | | 登録日 | 2004-05-19 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure Analysis of Recombinant Rat Kidney Long Chain Hydroxy Acid Oxidase.
Biochemistry, 44, 2005
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2RUS
 | | CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE, MG(II), AND ACTIVATOR CO2 AT 2.3-ANGSTROMS RESOLUTION | | 分子名称: | FORMYL GROUP, MAGNESIUM ION, RUBISCO (RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE) | | 著者 | Lundqvist, T, Schneider, G. | | 登録日 | 1991-10-11 | | 公開日 | 1991-10-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the ternary complex of ribulose-1,5-bisphosphate carboxylase, Mg(II), and activator CO2 at 2.3-A resolution.
Biochemistry, 30, 1991
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2BYZ
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2BZ3
 | | Structure of E.coli KAS I H298E mutant in complex with C12 fatty acid | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, LAURIC ACID, ... | | 著者 | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | | 登録日 | 2005-08-10 | | 公開日 | 2006-02-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
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6JZE
 | | Crystal structure of VASH2-SVBP complex with the magic triangle I3C | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | 登録日 | 2019-05-01 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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8RUC
 | | ACTIVATED SPINACH RUBISCO COMPLEXED WITH 2-CARBOXYARABINITOL BISPHOSPHATE | | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE | | 著者 | Andersson, I, Knight, S, Branden, C.-I. | | 登録日 | 1996-02-22 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Large structures at high resolution: the 1.6 A crystal structure of spinach ribulose-1,5-bisphosphate carboxylase/oxygenase complexed with 2-carboxyarabinitol bisphosphate.
J.Mol.Biol., 259, 1996
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1ZDL
 | | Crystal Structure of Mouse Thioredoxin Reductase Type 2 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 2, ... | | 著者 | Biterova, E.I, Turanov, A.A, Gladyshev, V.N, Barycki, J.J. | | 登録日 | 2005-04-14 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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6JZD
 | | Crystal structure of peptide-bound VASH2-SVBP complex | | 分子名称: | GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | 登録日 | 2019-05-01 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.479 Å) | | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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6JZC
 | | Structural basis of tubulin detyrosination | | 分子名称: | GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | | 著者 | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | | 登録日 | 2019-05-01 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
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1ZKQ
 | | Crystal structure of mouse thioredoxin reductase type 2 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 2, mitochondrial | | 著者 | Biterova, E.I, Turanov, A.A, Gladyshev, V.N, Barycki, J.J. | | 登録日 | 2005-05-03 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1DWU
 | | Ribosomal protein L1 | | 分子名称: | RIBOSOMAL PROTEIN L1 | | 著者 | Tishchenko, S.V, Nevskaya, N.A, Pavelyev, M.N, Nikonov, S.V, Garber, M.B, Piendl, W. | | 登録日 | 1999-12-13 | | 公開日 | 2000-12-07 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Ribosomal Protein L1 from Methanococcus Thermolithotrophicus. Functionally Important Structural Invariants on the L1 Surface
Acta Crystallogr.,Sect.D, 58, 2002
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2BYY
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2BZ4
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2HPA
 | | STRUCTURAL ORIGINS OF L(+)-TARTRATE INHIBITION OF HUMAN PROSTATIC ACID PHOSPHATASE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-PROPYL-TARTRAMIC ACID, ... | | 著者 | Lacount, M.W, Handy, G, Lebioda, L. | | 登録日 | 1998-09-11 | | 公開日 | 1998-09-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase.
J.Biol.Chem., 273, 1998
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4ETR
 | | X-ray structure of PA2169 from Pseudomonas aeruginosa | | 分子名称: | Putative uncharacterized protein | | 著者 | Schnell, R, Sandalova, T, Lindqvist, Y, Schneider, G. | | 登録日 | 2012-04-24 | | 公開日 | 2013-01-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
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1EK4
 | | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH DODECANOIC ACID TO 1.85 RESOLUTION | | 分子名称: | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I, LAURIC ACID | | 著者 | Olsen, J.G, Kadziola, A, Siggaard-Andersen, M, von Wettstein-Knowles, P, Larsen, S. | | 登録日 | 2000-03-06 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery.
Structure, 9, 2001
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1OUN
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2LXH
 | | NMR structure of the RING domain in ubiquitin ligase gp78 | | 分子名称: | E3 ubiquitin-protein ligase AMFR, ZINC ION | | 著者 | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | 登録日 | 2012-08-27 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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1PN0
 | | Phenol hydroxylase from Trichosporon cutaneum | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHENOL, ... | | 著者 | Enroth, C. | | 登録日 | 2003-06-12 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | High-resolution structure of phenol hydroxylase and correction of sequence errors.
Acta Crystallogr.,Sect.D, 59, 2003
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