1EOD
 
 | | CRYSTAL STRUCTURE OF THE N136D MUTANT OF A SHAKER T1 DOMAIN | | 分子名称: | POTASSIUM CHANNEL KV1.1 | | 著者 | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | | 登録日 | 2000-03-22 | | 公開日 | 2000-05-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Voltage dependent activation of potassium channels is coupled to T1 domain structure.
Nat.Struct.Biol., 7, 2000
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1J3I
 | | Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | | 登録日 | 2003-02-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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1J3K
 | | Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | | 登録日 | 2003-02-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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2LOR
 | | Backbone structure of human membrane protein TMEM141 | | 分子名称: | Transmembrane protein 141 | | 著者 | Bayrhuber, M, Klammt, C, Maslennikov, I, Riek, R, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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1J3J
 | | Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | | 登録日 | 2003-02-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
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2LON
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2LOM
 | | Backbone structure of human membrane protein HIGD1A | | 分子名称: | HIG1 domain family member 1A | | 著者 | Blain, K, Klammt, C, Maslennikov, I, Kwiatkowski, W, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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2LOS
 | | Backbone structure of human membrane protein TMEM14C | | 分子名称: | Transmembrane protein 14C | | 著者 | Klammt, C, Vajpai, N, Maslennikov, I, Riek, R, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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2LOQ
 | | Backbone structure of human membrane protein FAM14B (Interferon alpha-inducible protein 27-like protein 1) | | 分子名称: | Interferon alpha-inducible protein 27-like protein 1 | | 著者 | Klammt, C, Chui, E.J, Maslennikov, I, Kwiatkowski, W, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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2LOO
 | | Backbone structure of human membrane protein TMEM14A from NOE data | | 分子名称: | Transmembrane protein 14A | | 著者 | Eichmann, C, Klammt, C, Maslennikov, I, Riek, R, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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2LOP
 | | Backbone structure of human membrane protein TMEM14A | | 分子名称: | Transmembrane protein 14A | | 著者 | Eichmann, C, Klammt, C, Maslennikov, I, Kwiatkowski, W, Riek, R, Choe, S. | | 登録日 | 2012-01-26 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat.Methods, 9, 2012
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2MOI
 | | 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-04-26 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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2MOL
 | | 3D NMR structure of the cytoplasmic rhodanese domain of the full-length inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-04-27 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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2OGU
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7USE
 | | Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site | | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | | 登録日 | 2022-04-25 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
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7USC
 | | Cryo-EM structure of WAVE Regulatory Complex | | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, ... | | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | | 登録日 | 2022-04-25 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
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7USD
 | | Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex | | 分子名称: | Abl interactor 2, Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Ding, B, Yang, S, Chen, B, Chowdhury, S. | | 登録日 | 2022-04-25 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Nat Commun, 13, 2022
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2PPT
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3NJ4
 | | Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase | | 分子名称: | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S. | | 登録日 | 2010-06-17 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
J.Med.Chem., 54, 2011
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2MPN
 | | 3D NMR structure of the transmembrane domain of the full-length inner membrane protein YgaP from Escherichia coli | | 分子名称: | Inner membrane protein YgaP | | 著者 | Eichmann, C, Tzitzilonis, C, Bordignon, E, Maslennikov, I, Choe, S, Riek, R. | | 登録日 | 2014-05-29 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP from Escherichia coli.
J.Biol.Chem., 289, 2014
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4ECJ
 | | Crystal structure of glutathione s-transferase prk13972 (target efi-501853) from pseudomonas aeruginosa pacs2 complexed with glutathione | | 分子名称: | GLUTATHIONE, glutathione S-transferase | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-03-26 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal Structure of Glutathione S-Transferase Prk13972 from Pseudomonas Aeruginosa
To be Published
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4E4U
 | | Crystal structure of a putative Mandelate racemase/Muconate lactonizing enzyme (Target PSI-200780) from Burkholderia SAR-1 | | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Mandalate racemase/muconate lactonizing enzyme | | 著者 | Kumar, P.R, Bonanno, J, Chowdhury, S, Foti, R, Gizzi, A, Hammonds, J, Hillerich, B, Matikainen, B, Seidel, R, Toro, R, Zencheck, W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2012-03-13 | | 公開日 | 2012-04-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal structure of a putative MR/ML enzyme from Burkholderia SAR-1
to be published
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4EXJ
 | | Crystal structure of glutathione s-transferase like protein lelg_03239 (target efi-501752) from lodderomyces elongisporus | | 分子名称: | CHLORIDE ION, SULFATE ION, uncharacterized protein | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-04-30 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of glutathione s-transferase like protein lelg_03239 (target efi-501752) from lodderomyces elongisporus
To be Published
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4PUA
 | | Crystal Structure Of glutathione transferase YghU from Streptococcus pneumoniae ATCC 700669, complexed with glutathione, Target EFI-507284 | | 分子名称: | GLUTATHIONE, glutathione S-transferase | | 著者 | Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-03-12 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.708 Å) | | 主引用文献 | Crystal Structure Of glutathione transferase YghU from Streptococcus pneumoniae ATCC 700669, complexed with glutathione, Target EFI-507284
To be Published
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4Q60
 | | Crystal structure of a 4-hydroxyproline epimerase from Burkholderia Multivorans atcc 17616, target EFI-506586, open form, with bound pyrrole-2-carboxylate | | 分子名称: | GLYCEROL, PROLINE RACEMASE, PYRROLE-2-CARBOXYLATE | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Sojitra, S, Stead, M, Washington, E, Glenn, A.S, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-04-18 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF PROLINE RACEMASE Bmul_4447 FROM Burkholderia multivorans, TARGET EFI-506586
To be Published
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