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2V7W
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X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with 5'-fluorodeoxyadenosin
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2V7V
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X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from streptomyces cattleya complexed with 5'-fluorodeoxyadenosine
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2XG6
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Molecular insights into clinically isolated OmpC mutants and their role in multi-drug resistance
分子名称: OMPC, SULFATE ION
著者Lou, H, Naismith, J.H.
登録日2010-05-31
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
Plos One, 6, 2011
2XU2
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Crystal Structure of the hypothetical protein PA4511 from Pseudomonas aeruginosa
分子名称: CITRIC ACID, UPF0271 PROTEIN PA4511
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, White, M.F, Naismith, J.H.
登録日2010-10-14
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2VH3
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ranasmurfin
分子名称: GLYCEROL, RANASMURFIN, SULFATE ION, ...
著者Oke, M, Ching, R.T, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, Bloch Junior, C, Botting, C.H, Walsh, M.A, Latiff, A.A, Kennedy, M.W, Cooper, A, Naismith, J.H.
登録日2007-11-17
公開日2007-12-04
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Unusual Chromophore and Cross-Links in Ranasmurfin: A Blue Protein from the Foam Nests of a Tropical Frog.
Angew.Chem.Int.Ed.Engl., 47, 2008
2V7X
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X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE S158A mutant FROM STREPTOMYCES CATTLEYA COMPLEXED WITH the PRODUCTS, FDA and Met
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE
著者Robinson, D.A, Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2VHS
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Cathsilicatein, a chimera
分子名称: CATHSILICATEIN, SULFATE ION
著者Fairhead, M, Kowatz, T, McMahon, S.A, Carter, L.G, Oke, M, Johnson, K.A, Liu, H, Naismith, J.H, Wal, C.F.V.D.
登録日2007-11-24
公開日2008-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure and Silica Condensing Activities of Silicatein Alpha-Cathepsin L Chimeras.
Chem. Commun., 2008
2XBN
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BU of 2xbn by Molmil
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE
著者Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J.
登録日2010-04-13
公開日2010-05-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
2XU8
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Structure of Pa1645
分子名称: PA1645, SULFATE ION
著者Abdelli, W.B, Moynie, L, McMahon, S.A, Liu, H, Alphey, M.S, Naismith, J.H.
登録日2010-10-15
公開日2010-12-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
2YNK
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Wzi, an Outer Membrane Protein Involved in Group 1 Capsule Assembly in Escherichia coli, is a Carbohydrate Binding Beta-Barrel
分子名称: DODECANE, HEXANE, N-OCTANE, ...
著者Bushell, S.R, Mainprize, I.L, Wear, M.A, Lou, H, Kong, L, Davis, B, Bayley, H, Whitfield, C, Naismith, J.H.
登録日2012-10-16
公開日2013-05-15
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Wzi is an Outer Membrane Lectin that Underpins Group 1 Capsule Assembly in Escherichia Coli.
Structure, 21, 2013
2V7U
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BU of 2v7u by Molmil
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosylmethionine and chloride ion
分子名称: 5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE, CHLORIDE ION, S-ADENOSYLMETHIONINE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2X66
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The binary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway) and cyanide
分子名称: CYANIDE ION, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhu, X, van pee, K.-H, Naismith, J.H.
登録日2010-02-15
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily.
J.Biol.Chem., 285, 2010
2X67
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The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), tryptophan and cyanide
分子名称: CYANIDE ION, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhu, X, van pee, K.-H, Naismith, J.H.
登録日2010-02-15
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily.
J.Biol.Chem., 285, 2010
2X3D
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BU of 2x3d by Molmil
Crystal Structure of SSo6206 from Sulfolobus solfataricus P2
分子名称: SSO6206
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, McEwan, A.R, White, M.F, Naismith, J.H.
登録日2010-01-24
公開日2010-07-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Scottish Structural Proteomics Facility: targets, methods and outputs.
J. Struct. Funct. Genomics, 11, 2010
2X5H
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BU of 2x5h by Molmil
Crystal structure of the ORF131 L26M L51M double mutant from Sulfolobus islandicus rudivirus 1
分子名称: ORF 131, SULFATE ION
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Naismith, J.H, White, M.F.
登録日2010-02-08
公開日2010-07-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
2X0P
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CO-COMPLEX STRUCTURE OF ALCALIGIN BIOSYNTHETASE PROTEIN C (ALCC) WITH ADENOSINE FROM Bordetella bronchiseptica
分子名称: ADENOSINE, ALCALIGIN BIOSYNTHESIS PROTEIN, SULFATE ION
著者Schmelz, S, Challis, G.L, Naismith, J.H.
登録日2009-12-16
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Co-Complex Structure of Alcaligin Biosynthetase Protein C (Alcc) with Adenosine from Bordetella Bronchiseptica
To be Published
2WR8
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Structure of Pyrococcus horikoshii SAM hydroxide adenosyltransferase in complex with SAH
分子名称: PUTATIVE UNCHARACTERIZED PROTEIN PH0463, S-ADENOSYL-L-HOMOCYSTEINE
著者McMahon, S.A, Deng, H, O'Hagan, D, Johnson, K.A, Naismith, J.H.
登録日2009-08-31
公開日2009-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Mechanistic Insights Into Water Activation in Sam Hydroxide Adenosyltransferase (Duf-62).
Chembiochem, 10, 2009
2X0F
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Structure of WsaF in complex with dTDP-beta-L-Rha
分子名称: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, GLYCEROL, WSAF
著者Steiner, K, Hagelueken, G, Naismith, J.H.
登録日2009-12-08
公開日2010-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis of Substrate Binding in Wsaf, a Rhamnosyltransferase from Geobacillus Stearothermophilus.
J.Mol.Biol., 397, 2010
2X68
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The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), 7-Cl-L-tryptophan and cyanide
分子名称: 7-CHLOROTRYPTOPHAN, CYANIDE ION, PRNB, ...
著者Zhu, X, van pee, K.-H, Naismith, J.H.
登録日2010-02-15
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily.
J.Biol.Chem., 285, 2010
2X0Q
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CO-COMPLEX STRUCTURE OF ALCALIGIN BIOSYNTHESIS PROTEIN C (ALCC) WITH ATP FROM Bordetella bronchiseptica
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ALCALIGIN BIOSYNTHESIS PROTEIN, MAGNESIUM ION
著者Schmelz, S, Challis, G.L, Naismith, J.H.
登録日2009-12-16
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Co-Complex Structure of Alcaligin Biosynthesis Protein C (Alcc) with ATP from Bordetella Bronchiseptica
To be Published
2X3J
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CO-COMPLEX STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D (ACSD) WITH ATP AND N-CITRYL-ETHYLENEDIAMINE FROM PECTOBACTERIUM CHRYSANTHEMI
分子名称: (2S)-2-{2-[(2-AMINOETHYL)AMINO]-2-OXOETHYL}-2-HYDROXYBUTANEDIOIC ACID, ACSD, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Schmelz, S, Challis, G.L, Naismith, J.H.
登録日2010-01-25
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme Acsd.
J.Mol.Biol., 412, 2011
2BI7
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udp-galactopyranose mutase from Klebsiella pneumoniae oxidised FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-GALACTOPYRANOSE MUTASE
著者Beis, K, Srikannathasan, V, Naismith, J.
登録日2005-01-20
公開日2005-05-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Mycobacteria Tuberculosis and Klebsiella Pneumoniae Udp-Galactopyranose Mutase in the Oxidised State and Klebsiella Pneumoniae Udp-Galactopyranose Mutase in the (Active) Reduced State.
J.Mol.Biol., 348, 2005
8QXC
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BU of 8qxc by Molmil
Crystal structure of antibody Fab MIL-3 with PenG-Lys
分子名称: (2R,4S)-2-[(1R)-2-[[(5S)-5-acetamido-6-oxidanyl-6-oxidanylidene-hexyl]amino]-2-oxidanylidene-1-(2-phenylethanoylamino)ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Heavy chain of FAB MIL-3, Light chain of FAB MIL-3
著者Moynie, L, Naismith, J.H.
登録日2023-10-24
公開日2024-07-31
最終更新日2024-08-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted.
Nat Commun, 15, 2024
6QD6
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Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207
分子名称: CHLORIDE ION, Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207
著者Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkonig, A, Zogg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J.
登録日2018-12-31
公開日2019-12-18
最終更新日2021-01-13
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Nat.Methods, 18, 2021
6XUX
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Crystal structure of Megabody Mb-Nb207-cYgjK_NO
分子名称: CALCIUM ION, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody
著者Steyaert, J, Uchanski, T, Fischer, B.
登録日2020-01-21
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.90000641 Å)
主引用文献Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Nat.Methods, 18, 2021

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