8QXC
Crystal structure of antibody Fab MIL-3 with PenG-Lys
Summary for 8QXC
Entry DOI | 10.2210/pdb8qxc/pdb |
Descriptor | Heavy chain of FAB MIL-3, Light chain of FAB MIL-3, (2R,4S)-2-[(1R)-2-[[(5S)-5-acetamido-6-oxidanyl-6-oxidanylidene-hexyl]amino]-2-oxidanylidene-1-(2-phenylethanoylamino)ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | fab, penicillin, peng, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 6 |
Total formula weight | 164160.94 |
Authors | Moynie, L.,Naismith, J.H. (deposition date: 2023-10-24, release date: 2024-07-31, Last modification date: 2024-08-21) |
Primary citation | Deimel, L.P.,Moynie, L.,Sun, G.,Lewis, V.,Turner, A.,Buchanan, C.J.,Burnap, S.A.,Kutuzov, M.,Kobras, C.M.,Demyaneko, Y.,Mohammed, S.,Stracy, M.,Struwe, W.B.,Baldwin, A.J.,Naismith, J.,Davis, B.G.,Sattentau, Q.J. Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted. Nat Commun, 15:6851-6851, 2024 Cited by PubMed: 39127707DOI: 10.1038/s41467-024-51138-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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