8QXC

Crystal structure of antibody Fab MIL-3 with PenG-Lys

Summary for 8QXC

• Entry DOI: 10.2210/pdb8qxc/pdb
• Descriptor: Heavy chain of FAB MIL-3, Light chain of FAB MIL-3, (2R,4S)-2-[(1R)-2-[[(5S)-5-acetamido-6-oxidanyl-6-oxidanylidene-hexyl]amino]-2-oxidanylidene-1-(2-phenylethanoylamino)ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: fab, penicillin, peng, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 164160.94

Authors

Moynie, L.,Naismith, J.H. (deposition date: 2023-10-24, release date: 2024-07-31, Last modification date: 2024-08-21)

• Primary citation: Deimel, L.P.,Moynie, L.,Sun, G.,Lewis, V.,Turner, A.,Buchanan, C.J.,Burnap, S.A.,Kutuzov, M.,Kobras, C.M.,Demyaneko, Y.,Mohammed, S.,Stracy, M.,Struwe, W.B.,Baldwin, A.J.,Naismith, J.,Davis, B.G.,Sattentau, Q.J.; Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted.; Nat Commun, 15:6851-6851, 2024; PubMed: 39127707; DOI: 10.1038/s41467-024-51138-7

Experimental method

X-RAY DIFFRACTION (2.3 Å)