3V69
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![BU of 3v69 by Molmil](/molmil-images/mine/3v69) | Filia-N crystal structure | 分子名称: | Protein Filia | 著者 | Wang, J, Xu, M, Zhu, K, Li, L, Liu, X. | 登録日 | 2011-12-19 | 公開日 | 2012-02-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The N-terminus of FILIA Forms an Atypical KH Domain with a Unique Extension Involved in Interaction with RNA. Plos One, 7, 2012
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3L7V
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3LD2
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3O4O
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![BU of 3o4o by Molmil](/molmil-images/mine/3o4o) | Crystal structure of an Interleukin-1 receptor complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... | 著者 | Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. | 登録日 | 2010-07-27 | 公開日 | 2010-09-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the assembly and activation of IL-1beta with its receptors Nat.Immunol., 11, 2010
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3URG
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![BU of 3urg by Molmil](/molmil-images/mine/3urg) | The crystal structure of Anabaena CcbP | 分子名称: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, Alr1010 protein, SODIUM ION | 著者 | Fan, X.X, Liu, X, Su, X.D. | 登録日 | 2011-11-22 | 公開日 | 2012-11-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Ellman's reagent in promoting crystallization and structure determination of Anabaena CcbP. Acta Crystallogr.,Sect.F, 68, 2012
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2F7X
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![BU of 2f7x by Molmil](/molmil-images/mine/2f7x) | Protein Kinase A bound to (S)-2-(1H-Indol-3-yl)-1-[5-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine | 分子名称: | (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE, PKI, inhibitory peptide, ... | 著者 | Li, Q, Li, T, Zhu, G.D, Gong, J, Claibone, A, Dalton, C, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Bauch, J.L, Marsh, K.C, Bouska, J.J, Arries, S, De Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | 登録日 | 2005-12-01 | 公開日 | 2006-06-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Bioorg.Med.Chem.Lett., 16, 2006
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2GZ1
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![BU of 2gz1 by Molmil](/molmil-images/mine/2gz1) | Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP | 分子名称: | Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. | 登録日 | 2006-05-10 | 公開日 | 2006-08-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
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3NYJ
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![BU of 3nyj by Molmil](/molmil-images/mine/3nyj) | Crystal Structure Analysis of APP E2 domain | 分子名称: | Amyloid beta A4 protein, OSMIUM ION | 著者 | Ha, Y, Hu, J, Lee, S, Liu, X. | 登録日 | 2010-07-15 | 公開日 | 2011-06-01 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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3NR2
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![BU of 3nr2 by Molmil](/molmil-images/mine/3nr2) | Crystal structure of Caspase-6 zymogen | 分子名称: | Caspase-6 | 著者 | Su, X.-D, Wang, X.-J, Liu, X, Mi, W, Wang, K.-T. | 登録日 | 2010-06-30 | 公開日 | 2010-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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3OD5
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![BU of 3od5 by Molmil](/molmil-images/mine/3od5) | Crystal structure of active caspase-6 bound with Ac-VEID-CHO | 分子名称: | CACODYLATE ION, Caspase-6, peptide aldehyde inhibitor AC-VEID-CHO | 著者 | Wang, X.-J, Liu, X, Wang, K.-T, Cao, Q, Su, X.-D. | 登録日 | 2010-08-11 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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8IQ6
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![BU of 8iq6 by Molmil](/molmil-images/mine/8iq6) | Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | 登録日 | 2023-03-15 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
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8IQ4
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![BU of 8iq4 by Molmil](/molmil-images/mine/8iq4) | Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | 登録日 | 2023-03-15 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
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6KTR
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![BU of 6ktr by Molmil](/molmil-images/mine/6ktr) | Crystal structure of fibroblast growth factor 19 in complex with Fab | 分子名称: | Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ... | 著者 | Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J. | 登録日 | 2019-08-28 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.59775758 Å) | 主引用文献 | Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111, 2020
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7Y0F
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![BU of 7y0f by Molmil](/molmil-images/mine/7y0f) | Crystal structure of TMPRSS2 in complex with UK-371804 | 分子名称: | 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | 登録日 | 2022-06-04 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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7Y0E
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![BU of 7y0e by Molmil](/molmil-images/mine/7y0e) | Crystal structure of TMPRSS2 in complex with Camostat | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | 著者 | Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H. | 登録日 | 2022-06-04 | 公開日 | 2023-12-06 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
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7TBM
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![BU of 7tbm by Molmil](/molmil-images/mine/7tbm) | Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | DDX19, NUP107 CTD, NUP107 NTD, ... | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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7TBK
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![BU of 7tbk by Molmil](/molmil-images/mine/7tbk) | Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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7TBJ
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![BU of 7tbj by Molmil](/molmil-images/mine/7tbj) | Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-22 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (23 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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7TBL
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![BU of 7tbl by Molmil](/molmil-images/mine/7tbl) | Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC | 分子名称: | DDX19, ELYS, GLE1, ... | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-22 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (23 Å) | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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6JKK
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![BU of 6jkk by Molmil](/molmil-images/mine/6jkk) | Crystal structure of BubR1 kinase domain | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 | 著者 | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | 登録日 | 2019-03-01 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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3Q0E
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![BU of 3q0e by Molmil](/molmil-images/mine/3q0e) | Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase from Vibrio Cholerae with product of S-allyl-L-cysteine sulfoxide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ... | 著者 | Pavlovsky, A.G, Liu, X, Viola, R.E. | 登録日 | 2010-12-15 | 公開日 | 2012-02-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural characterization of inhibitors with selectivity against members of a homologous enzyme family. Chem.Biol.Drug Des., 79, 2012
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3PMR
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![BU of 3pmr by Molmil](/molmil-images/mine/3pmr) | Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 | 分子名称: | Amyloid-like protein 1, PHOSPHATE ION | 著者 | Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y. | 登録日 | 2010-11-17 | 公開日 | 2011-06-01 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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7TIC
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![BU of 7tic by Molmil](/molmil-images/mine/7tic) | Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | 登録日 | 2022-01-13 | 公開日 | 2022-02-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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7TKU
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![BU of 7tku by Molmil](/molmil-images/mine/7tku) | Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | 登録日 | 2022-01-17 | 公開日 | 2022-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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7TI8
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![BU of 7ti8 by Molmil](/molmil-images/mine/7ti8) | Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | 登録日 | 2022-01-13 | 公開日 | 2022-02-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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