3OHI
| Structure of Giardia fructose-1,6-biphosphate aldolase in complex with 3-hydroxy-2-pyridone | 分子名称: | ({3-hydroxy-2-oxo-4-[2-(phosphonooxy)ethyl]pyridin-1(2H)-yl}methyl)phosphonic acid, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | 著者 | Herzberg, O, Galkin, A. | 登録日 | 2010-08-17 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase. J.Inorg.Biochem., 105, 2010
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3V5Q
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3S5J
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8GDB
| Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein | 分子名称: | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Shenming, H, Mengyao, X, Lei, L, Jianqiang, M, Jinpeng, S. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GDC
| Cryo-EM Structure of the Prostaglandin E2 Receptor 3 Coupled to G Protein | 分子名称: | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Shenming, H, Mengyao, X, Lei, L, Yang, D, Shiyi, G, Jinpeng, S. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GDA
| Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein | 分子名称: | (2S,5R)-5-[(1E,3S)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-1-[6-(1H-tetrazol-5-yl)hexyl]pyrrolidin-2-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Shenming, H, Mengyao, X, Lei, L, Jiangqian, M, Sheng, C, Jinpeng, S. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GD9
| Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein | 分子名称: | 4-({2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]butyl}cyclopentyl]ethyl}sulfanyl)butanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Shenming, H, Mengyao, X, Lei, L, Yang, D, Sheng, C, Jinpeng, S. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proc.Natl.Acad.Sci.USA, 120, 2023
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8IER
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8IEN
| Cryo-EM structure of ATP13A2 in the E2-Pi state | 分子名称: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | 登録日 | 2023-02-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IEO
| Cryo-EM structure of ATP13A2 in the nominal E1P state | 分子名称: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | 登録日 | 2023-02-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IES
| Cryo-EM structure of ATP13A2 in the E1P-ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | 登録日 | 2023-02-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IEM
| Cryo-EM structure of ATP13A2 in the E2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | 登録日 | 2023-02-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
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8IEL
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8IEK
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8IT9
| Co-crystal structure of FTO bound to 22 | 分子名称: | 2-OXOGLUTARIC ACID, 2-[(2,6-diethyl-4-pyridin-4-yl-phenyl)amino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | 著者 | Yang, C.-G, Gan, J.H. | 登録日 | 2023-03-22 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J.Med.Chem., 66, 2023
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6M71
| SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-03-16 | 公開日 | 2020-04-01 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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5HS2
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6ILN
| Cryo-EM structure of full Echovirus 6 particle at PH 5.5 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | 登録日 | 2018-10-19 | 公開日 | 2019-05-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B. Cell, 177, 2019
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4YZG
| Structure of the Arabidopsis TAP38/PPH1, a state-transition phosphatase responsible for dephosphorylation of LHCII | 分子名称: | MANGANESE (II) ION, Protein phosphatase 2C 57, SULFATE ION | 著者 | Wei, X.P, Guo, J.T, Li, M, Liu, Z.F. | 登録日 | 2015-03-25 | 公開日 | 2015-04-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Mechanism Underlying the Specific Recognition between the Arabidopsis State-Transition Phosphatase TAP38/PPH1 and Phosphorylated Light-Harvesting Complex Protein Lhcb1 Plant Cell, 27, 2015
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7D3M
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7D3K
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7D3L
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7D3R
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4YZH
| Structure of the Arabidopsis TAP38/PPH1 in complex with pLhcb1 phosphopeptide substrate | 分子名称: | Chlorophyll a-b binding protein 2, chloroplastic, MANGANESE (II) ION, ... | 著者 | Wei, X.P, Guo, J.T, Li, M, Liu, Z.F. | 登録日 | 2015-03-25 | 公開日 | 2015-04-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Mechanism Underlying the Specific Recognition between the Arabidopsis State-Transition Phosphatase TAP38/PPH1 and Phosphorylated Light-Harvesting Complex Protein Lhcb1 Plant Cell, 27, 2015
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7E0B
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