4OHU
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![BU of 4ohu by Molmil](/molmil-images/mine/4ohu) | Crystal structure of Mycobacterium tuberculosis InhA in complex with inhibitor PT92 | 分子名称: | 2-(2-bromophenoxy)-5-hexylphenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Li, H.J, Pan, P, Lai, C.T, Liu, N, Yu, W, Garcia-Diaz, M, Simmerling, C, Tonge, P.J. | 登録日 | 2014-01-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | 主引用文献 | A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA. Acs Chem.Biol., 9, 2014
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6F2R
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![BU of 6f2r by Molmil](/molmil-images/mine/6f2r) | A heterotetramer of human HspB2 and HspB3 | 分子名称: | Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, ... | 著者 | Clark, A.R, Cole, A.R, Boelens, W.C, Keep, N.H, Slingsby, C. | 登録日 | 2017-11-27 | 公開日 | 2018-07-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3. J.Mol.Biol., 430, 2018
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2VJ4
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![BU of 2vj4 by Molmil](/molmil-images/mine/2vj4) | Methylated Shigella flexneri MxiC | 分子名称: | PROTEIN MXIC | 著者 | Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M. | 登録日 | 2007-12-06 | 公開日 | 2008-03-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues. J.Mol.Biol., 377, 2008
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1HY0
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![BU of 1hy0 by Molmil](/molmil-images/mine/1hy0) | CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 1 CRYSTALLIN (EYE LENS PROTEIN) | 分子名称: | DELTA CRYSTALLIN I, SULFATE ION | 著者 | Sampaleanu, L.M, Vallee, F, Slingsby, C, Howell, P.L. | 登録日 | 2001-01-17 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis. Biochemistry, 40, 2001
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2F12
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![BU of 2f12 by Molmil](/molmil-images/mine/2f12) | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor | 分子名称: | 3-hydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-14 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor To be Published
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2WF1
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![BU of 2wf1 by Molmil](/molmil-images/mine/2wf1) | Human BACE-1 in complex with 7-ethyl-N-((1S,2R)-2-hydroxy-3-(((3-(methyloxy)phenyl(methyl)amino)-1-(phenylmethyl)propyl)-1-methyl-3,4- dihydro-1H-(1,2,5)thiadiazepino(3,4,5-hi)indole-9-carboxamide 2,2- dioxide | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-7-ethyl-1-methyl-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide 2,2-dioxide | 著者 | Charrier, N, Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Hubbard, J, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2009-04-02 | 公開日 | 2009-05-19 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Second Generation of Bace-1 Inhibitors Part 2: Optimisation of the Non-Prime Side Substituent. Bioorg.Med.Chem.Lett., 19, 2009
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2F28
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![BU of 2f28 by Molmil](/molmil-images/mine/2f28) | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant | 分子名称: | CHLORIDE ION, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-15 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant To be Published
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2WF2
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![BU of 2wf2 by Molmil](/molmil-images/mine/2wf2) | Human BACE-1 in complex with 8-ethyl-N-((1S,2R)-2-hydroxy-3-(((3-(methyloxy)phenyl)methyl)amino)-1-(phenylmethyl)propyl)-1-methyl-3,4,7, 8-tetrahydro-1H,6H-(1,2,5)thiadiazepino(5,4,3-de)quinoxaline-10- carboxamide 2,2-dioxide | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-8-ETHYL-1-METHYL-3,4,7,8-TETRAHYDRO-1H,6H-[1,2,5]THIADIAZEPINO[5,4,3-DE]QUINOXALINE-10-CARBOXAMIDE 2,2-DIOXIDE | 著者 | Charrier, N, Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Hubbard, J, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2009-04-02 | 公開日 | 2009-05-19 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Second Generation of Bace-1 Inhibitors Part 2: Optimisation of the Non-Prime Side Substituent. Bioorg.Med.Chem.Lett., 19, 2009
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2F27
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![BU of 2f27 by Molmil](/molmil-images/mine/2f27) | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-15 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor To be Published
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1FJK
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![BU of 1fjk by Molmil](/molmil-images/mine/1fjk) | NMR Solution Structure of Phospholamban (C41F) | 分子名称: | CARDIAC PHOSPHOLAMBAN | 著者 | Lamberth, S, Griesinger, C, Schmid, H, Carafoli, E, Muenchbach, M, Vorherr, T, Krebs, J. | 登録日 | 2000-08-08 | 公開日 | 2000-09-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Solution Structure of Phospholamban HELV.CHIM.ACTA, 83, 2000
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1FJP
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![BU of 1fjp by Molmil](/molmil-images/mine/1fjp) | NMR Solution Structure of Phospholamban (C41F) | 分子名称: | CARDIAC PHOSPHOLAMBAN | 著者 | Lamberth, S, Griesinger, C, Schmid, H, Carafoli, E, Muenchbach, M, Vorherr, T, Krebs, J. | 登録日 | 2000-08-08 | 公開日 | 2000-09-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Solution Structure of Phospholamban HELV.CHIM.ACTA, 83, 2000
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1OJ5
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![BU of 1oj5 by Molmil](/molmil-images/mine/1oj5) | Crystal structure of the Nco-A1 PAS-B domain bound to the STAT6 transactivation domain LXXLL motif | 分子名称: | IODIDE ION, SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6, STEROID RECEPTOR COACTIVATOR 1A | 著者 | Razeto, A, Ramakrishnan, V, Giller, K, Lakomek, N, Carlomagno, T, Griesinger, C, Lodrini, M, Litterst, C.M, Pftizner, E, Becker, S. | 登録日 | 2003-07-02 | 公開日 | 2004-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the Stat6 Transactivation Domain J.Mol.Biol., 336, 2004
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2F10
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![BU of 2f10 by Molmil](/molmil-images/mine/2f10) | Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor | 分子名称: | 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, PHOSPHATE ION, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, McKimm-Breschkin, J, Colman, P.M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-14 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor To be Published
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6ERC
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![BU of 6erc by Molmil](/molmil-images/mine/6erc) | Peroxidase A from Dictyostelium discoideum (DdPoxA) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nicolussi, A, Mlynek, G, Furtmueller, P.G, Djinovic-Carugo, K, Obinger, C. | 登録日 | 2017-10-17 | 公開日 | 2017-12-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.50001836 Å) | 主引用文献 | Secreted heme peroxidase from Dictyostelium discoideum: Insights into catalysis, structure, and biological role. J. Biol. Chem., 293, 2018
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1HXH
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![BU of 1hxh by Molmil](/molmil-images/mine/1hxh) | COMAMONAS TESTOSTERONI 3BETA/17BETA HYDROXYSTEROID DEHYDROGENASE | 分子名称: | 3BETA/17BETA-HYDROXYSTEROID DEHYDROGENASE | 著者 | Benach, J, Filling, C, Oppermann, U.C.T, Roversi, P, Bricogne, G, Berndt, K.D, Jornvall, H, Ladenstein, R. | 登録日 | 2001-01-15 | 公開日 | 2002-12-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Structure of Bacterial 3beta/17beta-Hydroxysteroid Dehydrogenase at 1.2 A Resolution: A Model for
Multiple Steroid Recognition Biochemistry, 41, 2002
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1K5J
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![BU of 1k5j by Molmil](/molmil-images/mine/1k5j) | The Crystal Structure of Nucleoplasmin-Core | 分子名称: | Nucleoplasmin Core | 著者 | Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W. | 登録日 | 2001-10-10 | 公開日 | 2001-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly. Mol.Cell, 8, 2001
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2YOA
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![BU of 2yoa by Molmil](/molmil-images/mine/2yoa) | Synaptotagmin-1 C2B domain with phosphoserine | 分子名称: | CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ... | 著者 | Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R. | 登録日 | 2012-10-22 | 公開日 | 2013-03-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment Nat.Struct.Mol.Biol., 20, 2013
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2F26
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![BU of 2f26 by Molmil](/molmil-images/mine/2f26) | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant | 分子名称: | CHLORIDE ION, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-15 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant To be Published
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2F0Z
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![BU of 2f0z by Molmil](/molmil-images/mine/2f0z) | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor | 分子名称: | Sialidase 2, ZANAMIVIR | 著者 | Chavas, L.M.G, Kato, R, McKimm-Breschkin, J, Colman, P.M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-14 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor To be Published
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2F25
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![BU of 2f25 by Molmil](/molmil-images/mine/2f25) | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-15 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor To be Published
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7DEY
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![BU of 7dey by Molmil](/molmil-images/mine/7dey) | |
1HY1
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![BU of 1hy1 by Molmil](/molmil-images/mine/1hy1) | |
4OIM
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![BU of 4oim by Molmil](/molmil-images/mine/4oim) | Crystal structure of Mycobacterium tuberculosis InhA in complex with inhibitor PT119 in 2.4 M acetate | 分子名称: | 2-(2-CYANOPHENOXY)-5-HEXYLPHENOL, ACETATE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Li, H.J, Pan, P, Lai, C.T, Liu, N, Garcia-Diaz, M, Simmerling, C, Tonge, P.J. | 登録日 | 2014-01-20 | 公開日 | 2014-04-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.848 Å) | 主引用文献 | Time-Dependent Diaryl Ether Inhibitors of InhA: Structure-Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy. Chemmedchem, 9, 2014
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2F11
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![BU of 2f11 by Molmil](/molmil-images/mine/2f11) | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor | 分子名称: | 2-methylpropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | 著者 | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | 登録日 | 2005-11-14 | 公開日 | 2006-11-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor To be Published
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1AMM
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![BU of 1amm by Molmil](/molmil-images/mine/1amm) | 1.2 ANGSTROM STRUCTURE OF GAMMA-B CRYSTALLIN AT 150K | 分子名称: | GAMMA B-CRYSTALLIN | 著者 | Kumaraswamy, V.S, Lindley, P.F, Slingsby, C, Glover, I.D. | 登録日 | 1996-03-20 | 公開日 | 1996-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | An eye lens protein-water structure: 1.2 A resolution structure of gammaB-crystallin at 150 K. Acta Crystallogr.,Sect.D, 52, 1996
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