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1AJC
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THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-07-18
公開日1995-11-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Biochemistry, 34, 1995
1AJA
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THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-08-19
公開日1995-11-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
Biochemistry, 34, 1995
1B89
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CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE)
分子名称: PROTEIN (CLATHRIN HEAVY CHAIN)
著者Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K.
登録日1999-05-27
公開日1999-06-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Clathrin self-assembly is mediated by a tandemly repeated superhelix.
Nature, 399, 1999
4OHE
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LEOPARD Syndrome-Associated SHP2/G464A mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
4OHD
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LEOPARD Syndrome-Associated SHP2/A461T mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
1ZD0
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Crystal structure of Pfu-542154 conserved hypothetical protein
分子名称: MAGNESIUM ION, METHANOL, UNKNOWN ATOM OR ION, ...
著者Habel, J.E, Liu, Z.J, Horanyi, P.S, Florence, Q.J.T, Tempel, W, Zhou, W, Chen, L, Lee, D, Nguyen, J, Chang, S.H, Bereton, P, Izumi, M, Jenny Jr, F.E, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-04-13
公開日2005-05-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Pfu-542154 conserved hypothetical protein
To be Published
4OHI
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LEOPARD Syndrome-Associated SHP2/Q510E mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
2AEF
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Crystal Structures of the MthK RCK Domain in Ca2+ bound form
分子名称: CALCIUM ION, Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
4OHL
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LEOPARD Syndrome-Associated SHP2/T468M mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
2A4K
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3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137
分子名称: 3-oxoacyl-[acyl carrier protein] reductase, UNKNOWN ATOM OR ION
著者Zhou, W, Ebihara, A, Tempel, W, Yokoyama, S, Chen, L, Kuramitsu, S, Nguyen, J, Chang, S.-H, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-29
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137
To be Published
2CSL
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BU of 2csl by Molmil
Crystal structure of TTHA0137 from Thermus Thermophilus HB8
分子名称: protein translation initiation inhibitor
著者Wang, H, Murayama, K, Terada, T, Chen, L, Jin, Z, Chrzas, J, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-22
公開日2005-11-22
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of TTHA0137 from Thermus Thermophilus HB8
To be Published
2CW9
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BU of 2cw9 by Molmil
Crystal structure of human Tim44 C-terminal domain
分子名称: PENTAETHYLENE GLYCOL, translocase of inner mitochondrial membrane
著者Handa, N, Kishishita, S, Morita, S, Kinoshita, Y, Nagano, Y, Uda, H, Terada, T, Uchikubo, T, Takemoto, C, Jin, Z, Chrzas, J, Chen, L, Liu, Z.-J, Wang, B.-C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-17
公開日2005-12-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the human Tim44 C-terminal domain in complex with pentaethylene glycol: ligand-bound form.
Acta Crystallogr.,Sect.D, 63, 2007
2CYA
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BU of 2cya by Molmil
Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix
分子名称: SULFATE ION, Tyrosyl-tRNA synthetase
著者Kuratani, M, Sakai, H, Takahashi, M, Yanagisawa, T, Kobayashi, T, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Kuroishi, C, Kuramitsu, S, Terada, T, Bessho, Y, Shirouzu, M, Sekine, S.I, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-06
公開日2005-11-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
J.Mol.Biol., 355, 2005
6U6V
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BU of 6u6v by Molmil
Crystal structure of human PD-1H / VISTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation
著者Slater, B.T, Han, X, Chen, L, Xiong, Y.
登録日2019-08-30
公開日2020-01-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into T cell coinhibition by PD-1H (VISTA).
Proc.Natl.Acad.Sci.USA, 117, 2020
1DK4
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BU of 1dk4 by Molmil
CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE
分子名称: INOSITOL MONOPHOSPHATASE, PHOSPHATE ION, ZINC ION
著者Stec, B, Yang, H, Johnson, K.A, Chen, L, Roberts, M.F.
登録日1999-12-06
公開日2000-11-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase.
Nat.Struct.Biol., 7, 2000
2IMK
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Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
分子名称: Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE
著者Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
登録日2006-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IMI
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Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
分子名称: Epsilon-class Glutathione S-transferase, GLUTATHIONE
著者Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
登録日2006-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IL3
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Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
分子名称: Epsilon-class Glutathione S-transferase
著者Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
登録日2006-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
6WC2
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Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
分子名称: Homeobox protein Nkx-2.5, MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA
著者Lei, X, Chen, L.
登録日2020-03-29
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
2ZBV
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Crystal structure of uncharacterized conserved protein from Thermotoga maritima
分子名称: ADENOSINE, Uncharacterized conserved protein
著者Ebihara, A, Fujimoto, Y, Kagawa, W, Fujikawa, N, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-10-30
公開日2007-11-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of uncharacterized conserved protein from Thermotoga maritima
To be Published
1RD6
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Crystal Structure of S. Marcescens Chitinase A Mutant W167A
分子名称: Chitinase A
著者Aronson, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L.
登録日2003-11-05
公開日2004-12-07
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation.
Biosci.Biotechnol.Biochem., 70, 2006
1RYJ
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Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526.
分子名称: unknown
著者Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2003-12-22
公開日2004-02-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献AN NMR APPROACH TO STRUCTURAL PROTEOMICS
Proc.Natl.Acad.Sci.USA, 99, 2002
2ZKW
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Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21
分子名称: COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Yoshikawa, S, Kukimoto-Niino, M, Ito, K, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Shirouzu, M, Urushitani, M, Takahashi, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-03-31
公開日2009-03-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21
To be Published
1S9K
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Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
分子名称: Human IL-2 ARRE1 Promoter Element, Minus Strand, Plus Strand, ...
著者Wang, D, Stroud, J.C, Chen, L.
登録日2004-02-04
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site
To be Published
4OHH
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LEOPARD Syndrome-Associated SHP2/Q506P mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014

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