7ELN
| Structure of Csy-AcrIF24-dsDNA | 分子名称: | 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-04-12 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
|
|
7EQG
| Structure of Csy-AcrIF5 | 分子名称: | AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-05-01 | 公開日 | 2022-03-09 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition. Nat.Chem.Biol., 18, 2022
|
|
7C6U
| Crystal structure of SARS-CoV-2 complexed with GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | 著者 | Fu, L, Feng, Y, Qi, J, Gao, F.G. | 登録日 | 2020-05-22 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020
|
|
7C78
| |
7WDH
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine, phenol and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2021-12-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Engineering Cytochrome P450BM3 Enzymes for Direct Nitration of Unsaturated Hydrocarbons. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
7WDG
| Crystal structure of the P450 BM3 heme domain mutant F87L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, phenol and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2021-12-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Engineering Cytochrome P450BM3 Enzymes for Direct Nitration of Unsaturated Hydrocarbons. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
7Y0S
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine | 分子名称: | Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-TYR-TYR, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine To Be Published
|
|
7Y0U
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine | 分子名称: | Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-PHE-PHE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine To Be Published
|
|
7Y0R
| Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine To Be Published
|
|
7Y0Q
| |
7Y0P
| Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine To Be Published
|
|
7YJD
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-07-19 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine To Be Published
|
|
7EGN
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2021-03-24 | 公開日 | 2021-08-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | H-Bonding Networks Dictate the Molecular Mechanism of H2O2 Activation by P450 Acs Catalysis, 11, 2021
|
|
7XYB
| The cryo-EM structure of an AlpA-loaded complex | 分子名称: | AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Wen, A, Feng, Y. | 登録日 | 2022-06-01 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
|
|
7XYA
| The cryo-EM structure of an AlpA-loading complex | 分子名称: | AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Wen, A, Feng, Y. | 登録日 | 2022-06-01 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
|
|
7D7C
| CryoEM structure of gp55-dependent RNA polymerase-promoter open complex | 分子名称: | DNA (nontemplate strand), DNA (template strand), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Shi, J, Wen, A, Jin, S, Feng, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Transcription activation by a sliding clamp. Nat Commun, 12, 2021
|
|
7F75
| Cryo-EM structure of Spx-dependent transcription activation complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Feng, Y, Shi, J. | 登録日 | 2021-06-28 | 公開日 | 2021-10-13 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of transcription activation by the global regulator Spx. Nucleic Acids Res., 49, 2021
|
|
7D7D
| CryoEM structure of gp45-dependent transcription activation complex | 分子名称: | DNA (nontemplate strand), DNA (template strand), DNA polymerase clamp, ... | 著者 | Shi, J, Wen, A, Jin, S, Feng, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Transcription activation by a sliding clamp. Nat Commun, 12, 2021
|
|
7YWA
| Structure of DinI in complex with RecA filament | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), DNA damage-inducible protein I, MAGNESIUM ION, ... | 著者 | Gao, B, Feng, Y. | 登録日 | 2022-08-22 | 公開日 | 2022-12-21 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural basis for regulation of SOS response in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7CG5
| |
7CG8
| Structure of the sensor domain (short construct) of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, ACETATE ION, Anti-sigma factor RsgI, ... | 著者 | Dong, S, Feng, Y. | 登録日 | 2020-06-30 | 公開日 | 2021-06-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the sensor domain of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens To Be Published
|
|
7CG1
| |
7XM0
| |
7DM4
| Solution structure of ARID4B Tudor domain | 分子名称: | AT-rich interactive domain-containing protein 4B | 著者 | Ren, J, Yao, H, Hu, W, Perrett, S, Feng, Y, Gong, W. | 登録日 | 2020-12-02 | 公開日 | 2021-03-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the DNA-binding activity of human ARID4B Tudor domain. J.Biol.Chem., 296, 2021
|
|
7EIN
| SARS-CoV-2 main proteinase complex with microbial metabolite leupeptin | 分子名称: | 3C-like proteinase, leupeptin | 著者 | Fu, L.F, Feng, Y, Qi, J.X, Gao, G.F. | 登録日 | 2021-03-31 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs. Mbio, 12, 2021
|
|