8W9Y
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![BU of 8w9y by Molmil](/molmil-images/mine/8w9y) | The cryo-EM structure of human sphingomyelin synthase-related protein | 分子名称: | Sphingomyelin synthase-related protein 1 | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-09-06 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
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8W9W
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![BU of 8w9w by Molmil](/molmil-images/mine/8w9w) | The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide/phosphoethanolamine | 分子名称: | PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, Sphingomyelin synthase-related protein 1, ~{N}-[(~{Z},2~{S},3~{R})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamide | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-09-06 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
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8KAE
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![BU of 8kae by Molmil](/molmil-images/mine/8kae) | 16d-bound human SPNS2 | 分子名称: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, NbFab chain L, NbFab-H chain, ... | 著者 | He, Y, Duan, Y. | 登録日 | 2023-08-03 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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8HE4
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![BU of 8he4 by Molmil](/molmil-images/mine/8he4) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | 分子名称: | Chitin deacetylase, ZINC ION, ~{N}-oxidanylnaphthalene-1-carboxamide | 著者 | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | 登録日 | 2022-11-07 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HE2
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![BU of 8he2 by Molmil](/molmil-images/mine/8he2) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | 分子名称: | Chitin deacetylase, ZINC ION, tert-butyl N-[3-[[4-(oxidanylcarbamoyl)phenyl]methylamino]-3-oxidanylidene-propyl]carbamate | 著者 | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | 登録日 | 2022-11-07 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HE1
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![BU of 8he1 by Molmil](/molmil-images/mine/8he1) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | 分子名称: | BENZHYDROXAMIC ACID, Chitin deacetylase, ZINC ION | 著者 | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | 登録日 | 2022-11-07 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HFA
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![BU of 8hfa by Molmil](/molmil-images/mine/8hfa) | |
8HF9
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![BU of 8hf9 by Molmil](/molmil-images/mine/8hf9) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | 分子名称: | Chitin deacetylase, ZINC ION | 著者 | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | 登録日 | 2022-11-10 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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4YAQ
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![BU of 4yaq by Molmil](/molmil-images/mine/4yaq) | Crystal structure of a computationally optimized PG9 mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PG9_N100FY Fab heavy chain, ... | 著者 | Murrell, S, Julien, J.P, Wilson, I.A. | 登録日 | 2015-02-17 | 公開日 | 2015-06-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. J.Clin.Invest., 125, 2015
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5TRM
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![BU of 5trm by Molmil](/molmil-images/mine/5trm) | |
5TRL
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![BU of 5trl by Molmil](/molmil-images/mine/5trl) | |
8HLT
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![BU of 8hlt by Molmil](/molmil-images/mine/8hlt) | The co-crystal structure of DYRK2 with YK-2-99B | 分子名称: | (6-{[(4P)-4-(1,3-benzothiazol-5-yl)-5-fluoropyrimidin-2-yl]amino}pyridin-3-yl)(piperazin-1-yl)methanone, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Shen, H.T, Xiao, Y.B, Yuan, K, Yang, P, Li, Q.N. | 登録日 | 2022-12-01 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer. J.Med.Chem., 66, 2023
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8HZW
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![BU of 8hzw by Molmil](/molmil-images/mine/8hzw) | The NMR structure of noursinH11W peptide | 分子名称: | noursinH11W | 著者 | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | 登録日 | 2023-01-09 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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2AIU
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![BU of 2aiu by Molmil](/molmil-images/mine/2aiu) | Crystal Structure of Mouse Testicular Cytochrome C at 1.6 Angstrom | 分子名称: | Cytochrome c, testis-specific, PHOSPHATE ION, ... | 著者 | Liu, Z, Ye, S, Lin, H, Rao, Z, Liu, X.J. | 登録日 | 2005-08-01 | 公開日 | 2006-07-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis Proc.Natl.Acad.Sci.Usa, 103, 2006
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5WZE
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![BU of 5wze by Molmil](/molmil-images/mine/5wze) | The structure of Pseudomonas aeruginosa aminopeptidase PepP | 分子名称: | 1,2-ETHANEDIOL, ALANINE, Aminopeptidase P, ... | 著者 | Bao, R, Peng, C.T, Liu, L, He, L.H, Li, C.C, Li, T, Shen, Y.L, Zhu, Y.B, Song, Y.J. | 登録日 | 2017-01-17 | 公開日 | 2018-01-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | 主引用文献 | Structure-Function Relationship of Aminopeptidase P from Pseudomonas aeruginosa. Front Microbiol, 8, 2017
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3K30
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![BU of 3k30 by Molmil](/molmil-images/mine/3k30) | Histamine dehydrogenase from Nocardiodes simplex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, Histamine dehydrogenase, ... | 著者 | Scott, E.E, Reed, T.M, Limburg, J. | 登録日 | 2009-09-30 | 公開日 | 2010-05-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of histamine dehydrogenase from Nocardioides simplex. J.Biol.Chem., 285, 2010
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7VKT
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![BU of 7vkt by Molmil](/molmil-images/mine/7vkt) | cryo-EM structure of LTB4-bound BLT1 in complex with Gi protein | 分子名称: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Wang, N. | 登録日 | 2021-10-01 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of leukotriene B4 receptor 1 activation. Nat Commun, 13, 2022
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7YUB
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![BU of 7yub by Molmil](/molmil-images/mine/7yub) | S1P-bound human SPNS2 | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, NbFab-H-chain, NbFab-L-chain, ... | 著者 | He, Y, Duan, Y. | 登録日 | 2022-08-17 | 公開日 | 2023-09-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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7YUF
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![BU of 7yuf by Molmil](/molmil-images/mine/7yuf) | apo human SPNS2 | 分子名称: | NbFab H-chain, NbFab L-chain, Sphingosine-1-phosphate transporter SPNS2, ... | 著者 | He, Y, Duan, Y. | 登録日 | 2022-08-17 | 公開日 | 2023-09-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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7YUD
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![BU of 7yud by Molmil](/molmil-images/mine/7yud) | FTY720p-bound human SPNS2 | 分子名称: | (2~{S})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol, NbFab L-chain, NbFab-H-chain, ... | 著者 | He, Y, Duan, Y. | 登録日 | 2022-08-17 | 公開日 | 2023-09-06 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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6KXW
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![BU of 6kxw by Molmil](/molmil-images/mine/6kxw) | Crystal structure of human aquaporin AQP7 in bound to glycerol | 分子名称: | Aquaporin-7, GLYCEROL | 著者 | Zhang, L, Yao, D, Zhou, F, Zhang, Q, Zhou, L, Cao, Y. | 登録日 | 2019-09-13 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | The structural basis for glycerol permeation by human AQP7 Sci Bull (Beijing), 66, 2020
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6CB6
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![BU of 6cb6 by Molmil](/molmil-images/mine/6cb6) | |
6K6R
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![BU of 6k6r by Molmil](/molmil-images/mine/6k6r) | |
7C96
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![BU of 7c96 by Molmil](/molmil-images/mine/7c96) | Avr1d:GmPUB13 U-box | 分子名称: | RING-type E3 ubiquitin transferase, RxLR effector protein Avh6 | 著者 | Xing, W, Hu, Q, Zhou, J, Yao, D. | 登録日 | 2020-06-05 | 公開日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection. Proc.Natl.Acad.Sci.USA, 118, 2021
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7YFS
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![BU of 7yfs by Molmil](/molmil-images/mine/7yfs) | The NMR structure of noursin, a tricyclic ribosomal peptide containing a histidine-to-butyrine crosslink | 分子名称: | noursin | 著者 | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | 登録日 | 2022-07-09 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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