4DRU
 
 | | HCV NS5B in complex with macrocyclic INDOLE INHIBITOR | | 分子名称: | 13-cyclohexyl-3-methoxy-17,22-dimethyl-7H-10,6-(methanoiminothioiminobutanoiminomethano)indolo[2,1-a][2]benzazepine-14,23-dione 16,16-dioxide, GLYCEROL, RNA-directed RNA polymerase, ... | | 著者 | Cummings, M.D, Vendeville, S. | | 登録日 | 2012-02-17 | | 公開日 | 2012-04-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties.
Angew.Chem.Int.Ed.Engl., 51, 2012
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3R3O
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS T62A at cryogenic temperature and with high redundancy | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Caro, J.A, Schlessman, J.L, Garcia-Moreno E, B. | | 登録日 | 2011-03-16 | | 公開日 | 2011-03-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cavities determine the pressure unfolding of proteins.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4E7V
 | | The structure of R6 bovine insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Harris, P, Frankaer, C.G, Knudsen, M.V. | | 登録日 | 2012-03-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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6ER5
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8FG6
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4E7T
 | | The structure of T6 bovine insulin | | 分子名称: | Insulin A chain, Insulin B chain, ZINC ION | | 著者 | Harris, P, Frankaer, C.G, Knudsen, M.V. | | 登録日 | 2012-03-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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4E7U
 | | The structure of T3R3 bovine insulin | | 分子名称: | Insulin A chain, Insulin B chain, THIOCYANATE ION, ... | | 著者 | Harris, P, Frankaer, C.G, Knudsen, M.V. | | 登録日 | 2012-03-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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8TCS
 | | Structure of trehalose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1 | | 分子名称: | ACETATE ION, COBALT (II) ION, Xylose isomerase-like TIM barrel domain-containing protein, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-07-02 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
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8TDH
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8V31
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3ITP
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS F34K at cryogenic temperature | | 分子名称: | CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE | | 著者 | Khangulov, V.S, Schlessman, J.L, Heroux, A, Garcia-Moreno, E.B. | | 登録日 | 2009-08-28 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS F34K at cryogenic temperature
To be Published
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3IU4
 | | anti NeuGcGM3 ganglioside chimeric antibody chP3 | | 分子名称: | SULFATE ION, chP3 Fab heavy chain, chP3 Fab light chain | | 著者 | Eriksson, A, Okvist, M, Talavera, A, Krengel, U. | | 登録日 | 2009-08-29 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody.
Mol.Immunol., 46, 2009
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2XKN
 | | Crystal structure of the Fab fragment of the anti-EGFR antibody 7A7 | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ANTI-EGFR ANTIBODY 7A7 | | 著者 | Talavera, A, Mackenzie, J, Friemann, R, Krengel, U. | | 登録日 | 2010-07-09 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of the Fab Fragment of the Anti-Murine Egfr Antibody 7A7 and Exploration of its Receptor Binding Site.
Mol.Immunol., 48, 2011
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3G7M
 | | Structure of the thaumatin-like xylanase inhibitor TLXI | | 分子名称: | GLYCEROL, SODIUM ION, Xylanase inhibitor TL-XI | | 著者 | Vandermarliere, E, Courtin, C.M, Lammens, W, Schoepe, J, Strelkov, S.V. | | 登録日 | 2009-02-10 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Crystal structure of the noncompetitive xylanase inhibitor TLXI, member of the small thaumatin-like protein family.
Proteins, 78, 2010
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6I83
 | | Crystal structure of phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018366 | | 分子名称: | 4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret | | 著者 | Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M. | | 登録日 | 2018-11-19 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
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6I82
 | | Crystal structure of partially phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018412 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M. | | 登録日 | 2018-11-19 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
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1EUW
 | | ATOMIC RESOLUTION STRUCTURE OF E. COLI DUTPASE | | 分子名称: | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, ETHYL MERCURY ION, GLYCEROL | | 著者 | Gonzalez, A, Cedergren, E, Larsson, G, Persson, R. | | 登録日 | 2000-04-17 | | 公開日 | 2000-05-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Atomic resolution structure of Escherichia coli dUTPase determined ab initio.
Acta Crystallogr.,Sect.D, 57, 2001
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8TCR
 | | Structure of glucose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1 | | 分子名称: | COBALT (II) ION, MALONATE ION, Sugar phosphate isomerase, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-07-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
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8TCD
 | | Structure of Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1 | | 分子名称: | ACETATE ION, COBALT (II) ION, GLYCEROL, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-06-30 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
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8TCT
 | | Structure of 3K-GlcH bound Bacteroides thetaiotaomicron 3-Keto-beta-glucopyranoside-1,2-Lyase BT1 | | 分子名称: | 1,5-anhydro-D-ribo-hex-3-ulose, COBALT (II) ION, PHOSPHATE ION, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-07-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
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8TDE
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8TDA
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8TDF
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8TDI
 | | Structure of P2B11 Glucuronide-3-dehydrogenase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, P2B11 Glucuronide-3-dehydrogenase, ... | | 著者 | Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J. | | 登録日 | 2023-07-03 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
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3ZYZ
 | | Crystal structure of a glycoside hydrolase family 3 beta-glucosidase, Bgl1 from Hypocrea jecorina at 2.1A resolution. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCOSIDE GLUCOHYDROLASE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sandgren, M, Kaper, T, Mikkelsen, N.E, Hansson, H, Piens, K, Gudmundsson, M, Larenas, E, Kelemen, B, Karkehabadi, S. | | 登録日 | 2011-08-30 | | 公開日 | 2012-12-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical Characterization and Crystal Structures of a Fungal Family 3 Beta-Glucosidase, Cel3A from Hypocrea Jecorina.
J.Biol.Chem., 289, 2014
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