7TJG
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7TJM
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7TJD
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5H3J
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2OF4
| crystal structure of furanopyrimidine 1 bound to lck | 分子名称: | 5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK | 著者 | Martin, M.W. | 登録日 | 2007-01-02 | 公開日 | 2007-02-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties. Bioorg.Med.Chem.Lett., 17, 2007
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5JFB
| Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163 | 分子名称: | Scavenger receptor cysteine-rich type 1 protein M130 | 著者 | Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R. | 登録日 | 2016-04-19 | 公開日 | 2017-03-22 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection J. Virol., 91, 2017
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2OF2
| crystal structure of furanopyrimidine 8 bound to lck | 分子名称: | 2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK | 著者 | Martin, M.W. | 登録日 | 2007-01-02 | 公開日 | 2007-02-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties. Bioorg.Med.Chem.Lett., 17, 2007
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6M1I
| CryoEM structure of human PAC1 receptor in complex with PACAP38 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | 登録日 | 2020-02-26 | 公開日 | 2020-03-11 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
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2PPH
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5GMJ
| Crystal Structure of GRASP55 GRASP domain in complex with JAM-B C-terminus | 分子名称: | Golgi reassembly-stacking protein 2, Junctional adhesion molecule B | 著者 | Shi, N, Shi, X, Morelli, X, Betzi, S, Huang, X. | 登録日 | 2016-07-14 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.986 Å) | 主引用文献 | Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis PLoS Genet., 13, 2017
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6M1H
| CryoEM structure of human PAC1 receptor in complex with maxadilan | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | 登録日 | 2020-02-26 | 公開日 | 2020-03-11 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
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5GMI
| Crystal Structure of GRASP55 GRASP domain in complex with JAM-C C-terminus | 分子名称: | Golgi reassembly-stacking protein 2, Junctional adhesion molecule C | 著者 | Shi, N, Shi, X, Morelli, X, Betzi, S, Huang, X. | 登録日 | 2016-07-14 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis PLoS Genet., 13, 2017
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5GML
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5YWO
| Structure of JEV-2F2 Fab complex | 分子名称: | 2F2 heavy chain, 2F2 light chain, JEV E protein, ... | 著者 | Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z. | 登録日 | 2017-11-29 | 公開日 | 2018-03-21 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies Nat Microbiol, 3, 2018
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5YWF
| Crystal structure of 2H4 Fab | 分子名称: | 2H4 heavy chain, 2H4 light chain | 著者 | Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z. | 登録日 | 2017-11-29 | 公開日 | 2018-03-21 | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies Nat Microbiol, 3, 2018
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4WRS
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4XGY
| GFP based antibody (fluorobody) | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Green fluorescent protein, mAb LCDR3 | 著者 | Shi, N, Chen, Y.G, Wang, S.H. | 登録日 | 2015-01-03 | 公開日 | 2015-07-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.494 Å) | 主引用文献 | The structure of a GFP-based antibody (fluorobody) to TLH, a toxin from Vibrio parahaemolyticus. Acta Crystallogr.,Sect.F, 71, 2015
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6LZ7
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6LZ3
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4YRB
| mouse TDH mutant R180K with NAD+ bound | 分子名称: | L-threonine 3-dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | He, C, Li, F. | 登録日 | 2015-03-14 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
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7E3O
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4YRA
| mouse TDH in the apo form | 分子名称: | L-threonine 3-dehydrogenase, mitochondrial | 著者 | He, C, Li, F. | 登録日 | 2015-03-14 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
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4YR9
| mouse TDH with NAD+ bound | 分子名称: | GLYCEROL, L-threonine 3-dehydrogenase, mitochondrial, ... | 著者 | He, C, Li, F. | 登録日 | 2015-03-14 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis J.Struct.Biol., 192, 2015
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8ZHE
| SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-26 Fab, ... | 著者 | Yan, Q, Gao, X, Liu, B, Hou, R, He, P, Li, Z, Chen, Q, Wang, J, He, J, Chen, L, Zhao, J, Xiong, X. | 登録日 | 2024-05-10 | 公開日 | 2024-08-21 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants. Nat Commun, 15, 2024
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8ZHP
| Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H18 Fab, Heavy chain of R1-32 Fab, ... | 著者 | Yan, Q, Gao, X, Liu, B, Hou, R, He, P, Li, Z, Chen, Q, Wang, J, He, J, Chen, L, Zhao, J, Xiong, X. | 登録日 | 2024-05-11 | 公開日 | 2024-08-21 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants. Nat Commun, 15, 2024
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