5OWE
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5OWA
| Crystal structure of the human BRPF1 bromodomain in complex with BZ054 | 分子名称: | Peregrin, ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2017-08-31 | 公開日 | 2018-06-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors. Eur J Med Chem, 155, 2018
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6EKQ
| Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2 | 分子名称: | NITRATE ION, Peregrin, ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2017-09-26 | 公開日 | 2018-06-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors. Eur J Med Chem, 155, 2018
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6FQT
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6FUL
| Crystal structure of UTX complexed with 5-hydroxy-4-keto-1-methyl-picolinate | 分子名称: | 1-methyl-5-oxidanyl-4-oxidanylidene-pyridine-2-carboxylic acid, 2-(2-METHOXYETHOXY)ETHANOL, Lysine-specific demethylase 6A, ... | 著者 | Esposito, C, Sledz, P, Caflisch, A. | 登録日 | 2018-02-27 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | In Silico Identification of JMJD3 Demethylase Inhibitors. J Chem Inf Model, 58, 2018
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6G8F
| Crystal structure of UTX complexed with GSK-J1 | 分子名称: | 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Esposito, C, Sledz, P, Caflisch, A. | 登録日 | 2018-04-08 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | 主引用文献 | In Silico Identification of JMJD3 Demethylase Inhibitors. J Chem Inf Model, 58, 2018
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6FUK
| Crystal structure of UTX complexed with 5-carboxy-8-hydroxyquinoline | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 8-hydroxyquinoline-5-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... | 著者 | Esposito, C, Sledz, P, Caflisch, A. | 登録日 | 2018-02-27 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | In Silico Identification of JMJD3 Demethylase Inhibitors. J Chem Inf Model, 58, 2018
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6GLU
| Crystal structure of hMTH1 D120N in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | hMTH1 D120N in complex with LW14 To Be Published
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6GLF
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6GLL
| Crystal structure of hMTH1 N33A in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.395 Å) | 主引用文献 | hMTH1 N33A in complex with LW14 To Be Published
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6GLE
| Crystal structure of hMTH1 in complex with TH scaffold 1 in the presence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | 主引用文献 | hMTH1 in complex with TH scaffold 1 To Be Published
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6GLK
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6GLR
| Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the presence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 N33G in complex with TH scaffold 1 To Be Published
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6GLQ
| Crystal structure of hMTH1 N33G in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 N33G in complex with LW14. To Be Published
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6GLG
| Crystal structure of hMTH1 F27A in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.313 Å) | 主引用文献 | hMTH1 F27A in complex with LW14 To Be Published
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6GLM
| Crystal structure of hMTH1 N33A in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | hMTH1 N33A in complex with LW14 To Be Published
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6GLS
| Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | hMTH1 N33G in complex with TH scaffold 1. To Be Published
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6GLH
| Crystal structure of hMTH1 F27A in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | 主引用文献 | hMTH1 F27A in complex with LW14 To Be Published
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6GLP
| Crystal structure of hMTH1 N33G in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | hMTH1 N33G in complex with LW14 To Be Published
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6GLJ
| Crystal structure of hMTH1 F27A in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.301 Å) | 主引用文献 | hMTH1 F27A in complex with TH scaffold 1. To Be Published
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6GLO
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6GLV
| Crystal structure of hMTH1 D120N in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 D120N in complex with TH scaffold 1 To Be Published
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6GLI
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6GLN
| Crystal structure of hMTH1 N33A in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | hMTH1 N33A in complex with TH scaffold 1 To Be Published
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6GLT
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