5DSP
 
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7C6S
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7D1O
 | | Crystal structure of SARS-Cov-2 main protease with narlaprevir | | 分子名称: | (1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase | | 著者 | Fu, L.F, Feng, Y, Qi, J.X. | | 登録日 | 2020-09-15 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir.
Signal Transduct Target Ther, 6, 2021
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7D1M
 | | CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, DIMETHYL SULFOXIDE | | 著者 | Fu, L.F, Gilski, M, Shabalin, I, Gao, G.F, Qi, J.X. | | 登録日 | 2020-09-14 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
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7C6U
 | | Crystal structure of SARS-CoV-2 complexed with GC376 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | | 著者 | Fu, L, Feng, Y, Qi, J, Gao, F.G. | | 登録日 | 2020-05-22 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
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6IRR
 | | Solution structure of DISC1/ATF4 complex | | 分子名称: | Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 | | 著者 | Ye, F, Yu, C, Zhang, M. | | 登録日 | 2018-11-14 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.
Mol. Psychiatry, 2019
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7WKO
 | | ICP1 Csy1-2 complex | | 分子名称: | Csy1, Csy2 | | 著者 | Zhang, M, Peng, R. | | 登録日 | 2022-01-10 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7WKP
 | | ICP1 Csy4 | | 分子名称: | 3' stem loop crRNA, Csy4 | | 著者 | Zhang, M, Peng, R. | | 登録日 | 2022-01-10 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7WWV
 | | DNA bound-ICP1 Csy complex | | 分子名称: | Csy1, Csy2, Csy3, ... | | 著者 | Zhang, M, Peng, R. | | 登録日 | 2022-02-14 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7WWU
 | | ICP1 Csy complex | | 分子名称: | Csy1, Csy2, Csy3, ... | | 著者 | Zhang, M, Peng, R. | | 登録日 | 2022-02-14 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7WVI
 | | Crystal structure of SIA28 | | 分子名称: | Heavy chain of SIA28, Light chain of SIA28 | | 著者 | Chen, Y, Qi, J, Gao, G.F. | | 登録日 | 2022-02-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
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7WVG
 | | Crystal structure of H18 complexed with SIA28 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | | 著者 | Chen, Y, Qi, J, Gao, G.F. | | 登録日 | 2022-02-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
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7WVD
 | | Crystal structure of H14 complexed with SIA28 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | | 著者 | Chen, Y, Qi, J, Gao, G.F. | | 登録日 | 2022-02-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
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7WSB
 | | The ternary complex structure of FtmOx1 with a-ketoglutarate and 13-oxo-fumitremorgin B | | 分子名称: | 13-Oxofumitremorgin B, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... | | 著者 | Wang, J, Wang, X.Y, Wang, Y.Y, Yan, W.P. | | 登録日 | 2022-01-28 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues.
Jacs Au, 2, 2022
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5YI4
 | | Solution Structure of the DISC1/Ndel1 complex | | 分子名称: | Disrupted in schizophrenia 1 homolog,Nuclear distribution protein nudE-like 1 | | 著者 | Ye, F, Yu, C, Yu, C, Zhang, M. | | 登録日 | 2017-10-02 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis.
Neuron, 96, 2017
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5YS2
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5YSL
 | | Crystal structure of antibody 1H1 Fab | | 分子名称: | 1H1 heavy chain, 1H1 light chain | | 著者 | Hu, X.L, Yang, F.L. | | 登録日 | 2017-11-14 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.
PLoS Pathog., 13, 2017
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1D2E
 | | CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP | | 分子名称: | ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J. | | 登録日 | 1999-09-23 | | 公開日 | 1999-09-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
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7CDX
 | | Complex STRUCTURE OF A NOVEL VIRULENCE REGULATION FACTOR SghR with its effector sucrose | | 分子名称: | LacI-type transcription factor, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G. | | 登録日 | 2020-06-20 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
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7CE1
 | | Complex STRUCTURE OF TRANSCRIPTION FACTOR SghR with its COGNATE DNA | | 分子名称: | LacI-type transcription factor, promoter DNA | | 著者 | Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G. | | 登録日 | 2020-06-21 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
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7C8D
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7CDV
 | | STRUCTURE OF A NOVEL VIRULENCE REGULATION FACTOR SghR | | 分子名称: | LacI-type transcription factor | | 著者 | Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G. | | 登録日 | 2020-06-20 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
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7VXH
 | | Coxsackievirus B3 full particle at pH7.4 (VP3-234Q) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Wang, Q.L, Liu, C.C. | | 登録日 | 2021-11-12 | | 公開日 | 2022-01-19 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7VY0
 | | Coxsackievirus B3 full particle at pH7.4 (VP3-234N) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Wang, Q.L, Liu, C.C. | | 登録日 | 2021-11-13 | | 公開日 | 2022-01-19 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7VYM
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