1I3K
 
 | | MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | | 登録日 | 2001-02-15 | | 公開日 | 2001-06-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase.
J.Biol.Chem., 276, 2001
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1HZJ
 | | HUMAN UDP-GALACTOSE 4-EPIMERASE: ACCOMMODATION OF UDP-N-ACETYLGLUCOSAMINE WITHIN THE ACTIVE SITE | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | | 登録日 | 2001-01-25 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site.
J.Biol.Chem., 276, 2001
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1SO0
 | | Crystal structure of human galactose mutarotase complexed with galactose | | 分子名称: | aldose 1-epimerase, beta-D-galactopyranose | | 著者 | Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. | | 登録日 | 2004-03-12 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular structure of human galactose mutarotase
J.Biol.Chem., 279, 2004
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1R66
 | | Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound | | 分子名称: | CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TDP-glucose-4,6-dehydratase, ... | | 著者 | Allard, S.T.M, Cleland, W.W, Holden, H.M. | | 登録日 | 2003-10-14 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | High Resolution X-ray Structure of dTDP-Glucose 4,6-Dehydratase from Streptomyces venezuelae
J.Biol.Chem., 279, 2004
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1Q4S
 | | Crystal structure of Arthrobacter sp. strain SU 4-hydroxybenzoyl CoA thioesterase complexed with CoA and 4-hydroxybenzoic acid | | 分子名称: | COENZYME A, P-HYDROXYBENZOIC ACID, Thioesterase | | 著者 | Thoden, J.B, Zhuang, Z, Dunaway-Mariano, D, Holden, H.M. | | 登録日 | 2003-08-04 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Structure of 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. strain SU
J.Biol.Chem., 278, 2003
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1Q4U
 | | Crystal structure of 4-hydroxybenzoyl CoA thioesterase from arthrobacter sp. strain SU complexed with 4-hydroxybenzyl CoA | | 分子名称: | 1,2-ETHANEDIOL, 4-HYDROXYBENZYL COENZYME A, Thioesterase | | 著者 | Thoden, J.B, Zhuang, Z, Dunaway-Mariano, D, Holden, H.M. | | 登録日 | 2003-08-04 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Structure of 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. strain SU
J.Biol.Chem., 278, 2003
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1Q4T
 | | crystal structure of 4-hydroxybenzoyl CoA thioesterase from Arthrobacter sp. strain SU complexed with 4-hydroxyphenyl CoA | | 分子名称: | 1,2-ETHANEDIOL, 4-HYDROXYPHENACYL COENZYME A, CHLORIDE ION, ... | | 著者 | Thoden, J.B, Zhuang, Z, Dunaway-Mariano, D, Holden, H.M. | | 登録日 | 2003-08-04 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Structure of 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. strain SU
J.Biol.Chem., 278, 2003
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1JXZ
 | | Structure of the H90Q mutant of 4-Chlorobenzoyl-Coenzyme A Dehalogenase complexed with 4-hydroxybenzoyl-Coenzyme A (product) | | 分子名称: | 4-HYDROXYBENZOYL COENZYME A, 4-chlorobenzoyl Coenzyme A dehalogenase, CALCIUM ION, ... | | 著者 | Thoden, J.B, Zhang, W, Wei, Y, Luo, L, Taylor, K.L, Yang, G, Dunaway-Mariano, D, Benning, M.M, Holden, H.M. | | 登録日 | 2001-09-10 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Histidine 90 Function in 4-chlorobenzoyl-coenzyme A Dehalogenase Catalysis
Biochemistry, 40, 2001
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1PZ4
 | | The structural determination of an insect (mosquito) Sterol Carrier Protein-2 with a ligand bound C16 Fatty Acid at 1.35 A resolution | | 分子名称: | PALMITIC ACID, sterol carrier protein 2 | | 著者 | Dyer, D.H, Lovell, S, Thoden, J.B, Holden, H.M, Rayment, I, Lan, Q. | | 登録日 | 2003-07-09 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | The Structural Determination of an Insect Sterol Carrier Protein-2 with a Ligand-bound C16 Fatty Acid at 1.35A Resolution
J.Biol.Chem., 278, 2003
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1PKN
 | | STRUCTURE OF RABBIT MUSCLE PYRUVATE KINASE COMPLEXED WITH MN2+, K+, AND PYRUVATE | | 分子名称: | MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ... | | 著者 | Larsen, T.M, Laughlin, L.T, Holden, H.M, Rayment, I, Reed, G.H. | | 登録日 | 1994-03-25 | | 公開日 | 1995-01-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate.
Biochemistry, 33, 1994
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1JGM
 | | High Resolution Structure of the Cadmium-containing Phosphotriesterase from Pseudomonas diminuta | | 分子名称: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, CADMIUM ION, ... | | 著者 | Benning, M.M, Shim, H, Raushel, F.M, Holden, H.M. | | 登録日 | 2001-06-26 | | 公開日 | 2001-07-04 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta.
Biochemistry, 40, 2001
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1J7C
 | | STRUCTURE OF THE ANABAENA FERREDOXIN MUTANT E95K | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I | | 著者 | Hurley, J.K, Weber-Main, A.M, Stankovich, M.T, Benning, M.M, Thoden, J.B, Vanhooke, J.L, Holden, H.M, Chae, Y.K, Xia, B, Cheng, H, Markley, J.L, Martinez-Julvez, M, Gomez-Moreno, C, Schmeits, J.L, Tollin, G. | | 登録日 | 2001-05-16 | | 公開日 | 2001-05-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-function relationships in Anabaena ferredoxin: correlations between X-ray crystal structures, reduction potentials, and rate constants of electron transfer to ferredoxin:NADP+ reductase for site-specific ferredoxin mutants.
Biochemistry, 36, 1997
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1KEE
 | | Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthetase large chain, ... | | 著者 | Miles, B.W, Thoden, J.B, Holden, H.M, Raushel, F.M. | | 登録日 | 2001-11-15 | | 公開日 | 2001-12-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin.
J.Biol.Chem., 277, 2002
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1KVT
 | | UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL | | 分子名称: | DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | | 著者 | Thoden, J.B, Gulick, A.M, Holden, H.M. | | 登録日 | 1997-03-07 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry, 36, 1997
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1T36
 | | Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthase large chain, ... | | 著者 | Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. | | 登録日 | 2004-04-24 | | 公開日 | 2004-09-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Long-range allosteric transitions in carbamoyl phosphate synthetase.
Protein Sci., 13, 2004
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1KVQ
 | | UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL | | 分子名称: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | | 著者 | Thoden, J.B, Gulick, A.M, Holden, H.M. | | 登録日 | 1997-03-07 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry, 36, 1997
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1KJQ
 | | Crystal structure of glycinamide ribonucleotide transformylase in complex with Mg-ADP | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | | 登録日 | 2001-12-05 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.
J.Biol.Chem., 277, 2002
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1KJJ
 | | Crystal structure of glycniamide ribonucleotide transformylase in complex with Mg-ATP-gamma-S | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | | 登録日 | 2001-12-04 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.
J.Biol.Chem., 277, 2002
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1PIE
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1KJI
 | | Crystal structure of glycinamide ribonucleotide transformylase in complex with Mg-AMPPCP | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | | 登録日 | 2001-12-04 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.
J.Biol.Chem., 277, 2002
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1CS0
 | | Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... | | 著者 | Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. | | 登録日 | 1999-08-16 | | 公開日 | 1999-12-10 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
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1DV1
 | | STRUCTURE OF BIOTIN CARBOXYLASE (APO) | | 分子名称: | BIOTIN CARBOXYLASE, PHOSPHATE ION | | 著者 | Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. | | 登録日 | 2000-01-19 | | 公開日 | 2000-06-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
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1EK6
 | | STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, TETRAMETHYLAMMONIUM ION, ... | | 著者 | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | | 登録日 | 2000-03-06 | | 公開日 | 2000-05-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Biochemistry, 39, 2000
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1EK5
 | | STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE IN COMPLEX WITH NAD+ | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE 4-EPIMERASE | | 著者 | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | | 登録日 | 2000-03-06 | | 公開日 | 2000-05-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Biochemistry, 39, 2000
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1EZ1
 | | STRUCTURE OF ESCHERICHIA COLI PURT-ENCODED GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE COMPLEXED WITH MG, AMPPNP, AND GAR | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ACETATE ION, GLYCINAMIDE RIBONUCLEOTIDE, ... | | 著者 | Thoden, J.B, Firestine, S, Nixon, A, Benkovic, S.J, Holden, H.M. | | 登録日 | 2000-05-09 | | 公開日 | 2000-08-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular structure of Escherichia coli PurT-encoded glycinamide ribonucleotide transformylase.
Biochemistry, 39, 2000
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