1KEE

Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin

Summary for 1KEE

Entry DOI	10.2210/pdb1kee/pdb
Descriptor	Carbamoyl-phosphate synthetase large chain, Carbamoyl-phosphate synthetase small chain, MANGANESE (II) ION, ... (10 entities in total)
Functional Keywords	atp grasp, channeling, antibiotic, ligase
Biological source	Escherichia coli More
Total number of polymer chains	8
Total formula weight	645960.47
Authors	Miles, B.W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. (deposition date: 2001-11-15, release date: 2001-12-21, Last modification date: 2023-08-16)
Primary citation	Miles, B.W.,Thoden, J.B.,Holden, H.M.,Raushel, F.M. Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin. J.Biol.Chem., 277:4368-4373, 2002 Cited by PubMed: 11729189 DOI: 10.1074/jbc.M108582200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation