1I3K
MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE
Summary for 1I3K
Entry DOI | 10.2210/pdb1i3k/pdb |
Related | 1I3L 1I3M 1I3N |
Descriptor | UDP-GLUCOSE 4-EPIMERASE, CHLORIDE ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | galactosemia epimerase short-chain dehydrogenase, isomerase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 79581.23 |
Authors | Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. (deposition date: 2001-02-15, release date: 2001-06-20, Last modification date: 2023-08-09) |
Primary citation | Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem., 276:20617-20623, 2001 Cited by PubMed: 11279193DOI: 10.1074/jbc.M101304200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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