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7JWB
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BU of 7jwb by Molmil
SARS CoV2 Spike ectodomain with engineered trimerized VH binder
分子名称: Spike glycoprotein, autonomous human heavy chain variable domain
著者QCRG Structural Biology Consortium
登録日2020-08-25
公開日2020-10-07
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Nat.Chem.Biol., 17, 2021
8TZN
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BU of 8tzn by Molmil
Crystal structure of 10E8-GT10.2 HIV-1 MPER scaffold in complex with a non-human primate W3-01 Fab
分子名称: 10E8-GT10.2 MPER scaffold, W3-01 Fab Heavy Chain, W3-01 Fab Light Chain
著者Lee, C.C.D, Wilson, I.A.
登録日2023-08-27
公開日2024-06-12
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8TZW
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BU of 8tzw by Molmil
Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
分子名称: 10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8U03
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BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
分子名称: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8U08
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BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
分子名称: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
分子名称: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Cho, S.Y, Wilson, I.A.
登録日2023-11-22
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
6M1K
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BU of 6m1k by Molmil
USP7 in complex with a novel inhibitor
分子名称: Ubiquitin carboxyl-terminal hydrolase 7, methyl 4-[[4-[[3-[4-(aminomethyl)phenyl]-2-methyl-7-oxidanylidene-pyrazolo[4,3-d]pyrimidin-6-yl]methyl]-4-oxidanyl-piperidin-1-yl]methyl]-3-chloranyl-benzoate
著者Liu, S.J, Zhou, X.Y, Li, M.L, Sun, H.B, Wen, X.A.
登録日2020-02-26
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.255 Å)
主引用文献N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.
Eur.J.Med.Chem., 199, 2020
5HSO
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BU of 5hso by Molmil
Crystal structure of MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN Rv2887 complex with DNA
分子名称: DNA (30-MER), the upstream sequence of Rv0560c, Uncharacterized HTH-type transcriptional regulator Rv2887
著者Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J.
登録日2016-01-26
公開日2017-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
7MU5
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BU of 7mu5 by Molmil
Human DCTPP1 bound to Triptolide
分子名称: MAGNESIUM ION, dCTP pyrophosphatase 1, triptolide
著者Hauk, G, Berger, J.M.
登録日2021-05-14
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance
To Be Published
5HSM
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BU of 5hsm by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887
分子名称: SULFATE ION, Uncharacterized HTH-type transcriptional regulator Rv2887
著者Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J.
登録日2016-01-26
公開日2017-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
6L56
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BU of 6l56 by Molmil
Fe(II) loaded Tegillarca granosa ferritin
分子名称: FE (II) ION, FE (III) ION, Ferritin, ...
著者Jiang, Q.Q, Su, X.R, Ming, T.H, Huan, H.S.
登録日2019-10-22
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85300577 Å)
主引用文献Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Front Mol Biosci, 9, 2022
6LCG
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BU of 6lcg by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: DI(HYDROXYETHYL)ETHER, N-carbamoyl-D-amino-acid hydrolase
著者Liu, Y.F, Ni, Y, Xu, G.C, Dai, W.
登録日2019-11-18
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
6LEI
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BU of 6lei by Molmil
Structure of D-carbamoylase from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C.
登録日2019-11-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
6L55
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BU of 6l55 by Molmil
Recombinant Tegillarca granosa ferritin
分子名称: FE (III) ION, FORMIC ACID, Ferritin, ...
著者Jiang, Q.Q, Su, X.R, Ming, T.H, Huan, H.S.
登録日2019-10-22
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78304863 Å)
主引用文献Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Front Mol Biosci, 9, 2022
6KZY
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BU of 6kzy by Molmil
Cu(II) loaded Tegillarca granosa ferritin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, Ferritin, ...
著者Jiang, Q.Q, Su, X.R, Ming, T.H, Huan, H.S.
登録日2019-09-25
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.30057073 Å)
主引用文献Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Front Mol Biosci, 9, 2022
6LED
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BU of 6led by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C.
登録日2019-11-25
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
6L58
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BU of 6l58 by Molmil
Cu(II) loaded Tegillarca granosa M-ferritin soaked with Fe(II)
分子名称: COPPER (II) ION, Ferritin
著者Jiang, Q.Q, Su, X.R, Ming, T.H, Huan, H.S.
登録日2019-10-22
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.90270972 Å)
主引用文献Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa.
Front Mol Biosci, 9, 2022
6LE2
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BU of 6le2 by Molmil
Structure of D-carbamoylase mutant from Nitratireductor indicus
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-carbamoyl-D-amino-acid hydrolase
著者Ni, Y, Liu, Y.F, Xu, G.C, Dai, W.
登録日2019-11-23
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel
Acs Catalysis, 10, 2020
8WUI
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BU of 8wui by Molmil
SKOR D312N L271P double mutation
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR
著者Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G.
登録日2023-10-20
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel.
Plant Commun., 2024
8WTZ
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BU of 8wtz by Molmil
potassium outward rectifier channel SKOR
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR
著者Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G.
登録日2023-10-19
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel.
Plant Commun., 2024
6MTO
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BU of 6mto by Molmil
Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold
分子名称: Antibody VRC42.01 Fab heavy chain, Antibody VRC42.01 Fab light chain, VRC42 epitope T117-F scaffold
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.634 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTR
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BU of 6mtr by Molmil
Crystal structure of VRC43.01 Fab
分子名称: Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTS
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BU of 6mts by Molmil
Crystal structure of VRC43.03 Fab
分子名称: Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.437 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTP
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BU of 6mtp by Molmil
Crystal structure of VRC42.04 Fab in complex with gp41 peptide
分子名称: Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.036 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTT
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BU of 6mtt by Molmil
Crystal structure of VRC46.01 Fab in complex with gp41 peptide
分子名称: Antibody VRC46.01 Fab heavy chain, Antibody VRC46.01 Fb light chain, RV217 founder virus gp41 peptide
著者Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Veradi, R, Doria-Rose, N.A, Kwong, P.D.
登録日2018-10-21
公開日2019-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019

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