5XMK
 
 | | Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1 | | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | | 登録日 | 2017-05-15 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
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5C8C
 | | Crystal structure of recombinant coxsackievirus A16 capsid | | 分子名称: | CHLORIDE ION, POTASSIUM ION, STEARIC ACID, ... | | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2015-06-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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5VBL
 | | Structure of apelin receptor in complex with agonist peptide | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apelin receptor,Rubredoxin,Apelin receptor Chimera, ZINC ION, ... | | 著者 | Ma, Y, Yue, Y, Ma, Y, Zhang, Q, Zhou, Q, Song, Y, Shen, Y, Li, X, Ma, X, Li, C, Hanson, M.A, Han, G.W, Sickmier, E.A, Swaminath, G, Zhao, S, Stevems, R.C, Hu, L.A, Zhong, W, Zhang, M, Xu, F. | | 登録日 | 2017-03-29 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Apelin Control of the Human Apelin Receptor
Structure, 25, 2017
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5XWY
 | | Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex | | 分子名称: | A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) | | 著者 | Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M. | | 登録日 | 2017-06-30 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
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5XMI
 | | Cryo-EM Structure of the ATP-bound VPS4 mutant-E233Q hexamer (masked) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4 | | 著者 | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | | 登録日 | 2017-05-15 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
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2OBR
 | | Crystal Structures of P Domain of Norovirus VA387 | | 分子名称: | Capsid protein | | 著者 | Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z. | | 登録日 | 2006-12-20 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the recognition of blood group trisaccharides by norovirus.
J.Virol., 81, 2007
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8JOJ
 | | Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 in complex with 9,11-epoxy-17-hydroxypregn-4-ene-3,20-dione actate | | 分子名称: | 3-ketosteroid dehydrogenase, 9,11-epoxy-17-hydroxypregn-4-ene-3,20-dione actate, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hu, Y.L, Li, X, Cheng, X.Y, Song, S.K, Su, Z.D. | | 登録日 | 2023-06-07 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.819 Å) | | 主引用文献 | Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 in complex with 9,11-epoxy-17-hydroxypregn-4-ene-3,20-dione actate
To Be Published
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2OQV
 | | Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine | | 分子名称: | (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) | | 著者 | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D. | | 登録日 | 2007-02-01 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors.
J.Med.Chem., 50, 2007
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3T89
 | | Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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7R8D
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7R8A
 | | The structure of human ABCG5/ABCG8 purified from mammalian cells | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R88
 | | The structure of human ABCG5-I529W/ABCG8-WT | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R8B
 | | The structure of human ABCG5/ABCG8 supplemented with cholesterol | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R8E
 | | The structure of human ABCG1 E242Q complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Isoform 4 of ATP-binding cassette sub-family G member 1, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R89
 | | The structure of human ABCG5/ABCG8 purified from yeast | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R87
 | | The structure of human ABCG5-WT/ABCG8-I419E | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R8C
 | | The structure of human ABCG1 | | 分子名称: | Isoform 4 of ATP-binding cassette sub-family G member 1 | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8TZS
 | | Structure of human WLS | | 分子名称: | Protein wntless homolog | | 著者 | Qi, X, Hu, Q, Li, X. | | 登録日 | 2023-08-27 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Cell, 186, 2023
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8TZR
 | | Structure of human Wnt3a bound to WLS and CALR | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calreticulin, PALMITOLEIC ACID, ... | | 著者 | Qi, X, Hu, Q, Li, X. | | 登録日 | 2023-08-27 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of human Wnt3a bound to WLS and CALR
To Be Published
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8TZP
 | | Structure of human Wnt7a bound to WLS and RECK | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PALMITOLEIC ACID, Protein Wnt-7a, ... | | 著者 | Qi, X, Hu, Q, Li, X. | | 登録日 | 2023-08-27 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Cell, 186, 2023
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8TZO
 | | Structure of human Wnt7a bound to WLS and CALR | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, Calreticulin, ... | | 著者 | Qi, X, Hu, Q, Li, X. | | 登録日 | 2023-08-27 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Cell, 186, 2023
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3T8B
 | | Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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3T8A
 | | Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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3T88
 | | Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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2OQI
 | | Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine | | 分子名称: | (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) | | 著者 | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D, Backes, B.J, Lai, C, Lubben, T.H, Ballaron, S.J, Beno, D.W, Kempf-Grote, A.J, Sham, H.L, Trevillyan, J.M. | | 登録日 | 2007-01-31 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors.
J.Med.Chem., 50, 2007
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