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6TZ6
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Crystal Structure of Candida Albicans Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
分子名称: 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ...
著者Fox III, D, Lukacs, C.M.
登録日2019-08-10
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
5B8I
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Crystal structure of Calcineurin A and Calcineurin B in complex with FKBP12 and FK506 from Coccidioides immitis RS
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D, Dranow, D.M, Lorimer, D.D, Edwards, T.E.
登録日2015-05-03
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
3BT9
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crystal structure of QacR(E57Q) bound to Dequalinium
分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION
著者Shumacher, M.A, Schuman, J.T, Brennan, R.G.
登録日2007-12-28
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
Biochemistry, 47, 2008
5KHD
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BU of 5khd by Molmil
Structure of 1.75 A BldD C-domain-c-di-GMP complex
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.
登録日2016-06-14
公開日2016-06-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7501 Å)
主引用文献Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell, 158, 2014
5J6E
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BU of 5j6e by Molmil
Structure of disulfide crosslinked A. fumigatus FKBP12(V91C)
分子名称: FK506-binding protein 1A
著者Schumacher, M.
登録日2016-04-04
公開日2016-09-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
Mbio, 7, 2016
4JG4
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BU of 4jg4 by Molmil
Ligand concentration regulates the pathways of coupled protein folding and binding
分子名称: PYROPHOSPHATE, Ribonuclease P protein component
著者Tonthat, N.K.
登録日2013-02-28
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献Ligand concentration regulates the pathways of coupled protein folding and binding.
J.Am.Chem.Soc., 136, 2014
5KK1
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BU of 5kk1 by Molmil
Structure of pNOB8 AspA-DNA complex.
分子名称: AspA, DNA (31-MER)
著者Schumacher, M.
登録日2016-06-20
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献to be published
To Be Published
1LBI
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BU of 1lbi by Molmil
LAC REPRESSOR
分子名称: LAC REPRESSOR
著者Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
登録日1996-02-17
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBG
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LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY
分子名称: DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), PROTEIN (LACTOSE OPERON REPRESSOR)
著者Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
登録日1996-01-03
公開日1996-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (4.8 Å)
主引用文献Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1LBH
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BU of 1lbh by Molmil
INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
著者Lewis, M, Chang, G, Horton, N.C, Kercher, M.A, Pace, H.C, Lu, P.
登録日1996-02-17
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Science, 271, 1996
1DL7
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BU of 1dl7 by Molmil
THE STRUCTURAL BASIS OF REPERTOIRE SHIFT IN AN IMMUNE RESPONSE TO PHOSPHOCHOLINE
分子名称: P-NITROPHENYL-PHOSPHOCHOLINE, PROTEIN (ANTIBODY M3C65 (HEAVY CHAIN)), PROTEIN (ANTIBODY M3C65 (LIGHT CHAIN))
著者Schumacher, M, Brown, M.
登録日1999-12-08
公開日2000-12-13
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The structural basis of repertoire shift in an immune response to phosphocholine.
J.Exp.Med., 191, 2000
5DXN
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Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2
分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DX9
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BU of 5dx9 by Molmil
Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans
分子名称: 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXO
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BU of 5dxo by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3
分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXF
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BU of 5dxf by Molmil
Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain
分子名称: trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.563 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXI
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BU of 5dxi by Molmil
Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ...
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
8SSH
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BU of 8ssh by Molmil
MtrR from Neisseria gonorrhoeae bound to Ethinyl Estradiol
分子名称: Ethinyl estradiol, HTH-type transcriptional regulator MtrR, PHOSPHATE ION
著者Hooks, G.M, Brennan, R.G.
登録日2023-05-08
公開日2024-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR.
Nat Commun, 15, 2024
7JNP
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BU of 7jnp by Molmil
MtrR bound to the rpoH operator from Neisseria gonorrhoeae
分子名称: CALCIUM ION, DNA (5'-D(*TP*AP*CP*AP*TP*AP*CP*GP*TP*GP*GP*TP*TP*GP*TP*AP*TP*GP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*TP*AP*CP*AP*AP*CP*CP*AP*CP*GP*TP*AP*TP*GP*TP*A)-3'), ...
著者Beggs, G.A, Shafer, W.M, Brennan, R.G.
登録日2020-08-05
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Nucleic Acids Res., 49, 2021
7JU3
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BU of 7ju3 by Molmil
MtrR bound to the mtrCDE operator from Neisseria gonorrhoeae
分子名称: CALCIUM ION, DNA (5'-D(*AP*CP*AP*TP*AP*CP*AP*CP*GP*AP*TP*TP*GP*CP*AP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*CP*GP*TP*GP*CP*AP*AP*TP*CP*GP*TP*GP*TP*AP*TP*GP*T)-3'), ...
著者Beggs, G.A, Shafer, W.M, Brennan, R.G.
登録日2020-08-19
公開日2021-03-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.
Nucleic Acids Res., 49, 2021
1HK9
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Crystal structure of the Hfq protein from Escherichia coli
分子名称: PROTEIN HFQ
著者Sauter, C, Basquin, J, Suck, D.
登録日2003-03-06
公開日2003-07-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Sm-Like Proteins in Eubacteria: The Crystal Structure of the Hfq Protein from Escherichia Coli
Nucleic Acids Res., 31, 2003
1KKD
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Solution structure of the calmodulin binding domain (CaMBD) of small conductance Ca2+-activated potassium channels (SK2)
分子名称: Small conductance calcium-activated potassium channel protein 2
著者Wissmann, R, Bildl, W, Neumann, H, Rivard, A.F, Kloecker, N, Weitz, D, Schulte, U, Adelman, J.P, Bentrop, D, Fakler, B.
登録日2001-12-07
公開日2001-12-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin.
J.Biol.Chem., 277, 2002

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